Results 31 to 40 of about 3,700 (219)
Age-related changes of cholestanol and lathosterol plasma concentrations: an explorative study
Lipids in Health and Disease, 2019 Background Cerebrotendinous xanthomatosis (CTX) and Lathosterolosis represent two treatable inherited disorders of cholesterol metabolism that are characterized by the accumulation of cholestanol and lathosterol, respectively.
Monica Gelzo +7 more
doaj +1 more source
Neurología (English Edition), 2011 Introduction: Cerebrotendinous xanthomatosis (CTX) is an autosomal recessive disease caused by a deficiency of mitochondrial enzyme sterol 27-hydrolylase.
B. Pilo de la Fuente +8 more
doaj +1 more source
Biomedicines, 2023 Cerebrotendinous xanthomatosis (CTX) is a genetic disorder of the cholesterol metabolic pathway, most often associated with variants in the CYP27A1 gene.
Petar Brlek +8 more
doaj +1 more source
The microstratigraphy of middens: capturing daily routine in rubbish at Neolithic Çatalhöyük, Turkey [PDF]
, 2011 Microstratigraphy — the sequencing of detailed biological signals on site — is an important new approach being developed in the Çatalhöyük project. Here the authors show how microscopic recording of the strata and content of widespread middens on the ...
Almond, Matthew J. +3 more
core +1 more source
Journal of Lipid Research, 1982 The cholesterol and cholestanol biosynthetic pathways and the control of cholesterolgenesis were investigated in skin fibroblasts, from patients with cerebrotendinous xanthomatosis (CTX) and from normal subjects, growth in a lipoprotein deficient (d less
G S Tint, G Salen
doaj +1 more source
Low density lipoprotein cholesterol is inversely correlated with abdominal visceral fat area: a magnetic resonance imaging study [PDF]
, 2011 Background Visceral Fat Area (VFA) is an independent predictor of coronary disease. While low density lipoprotein cholesterol (LDL-C) is used to determine risk and guide therapy, its accuracy fails in obese patients who may have low LDL-C despite high ...
Michel R Hoenig +4 more
core +1 more source
Metabolism of coprostanol-C14 and cholestanol-4-C14 in man
Journal of Lipid Research, 1963 Coprostanol-C14, biosynthetically prepared, was administered orally to two patients, and cholestanol-4-C14 was administered to one of them 10 months later.
R.S. Rosenfeld +2 more
doaj +1 more source
Sterol concentration and distribution in sunflower seeds (Helianthus annuus L.) during seed development [PDF]
, 2010 Sunflower seeds are currently used for edible oil production. Among oil minor compounds, phytosterols are of special interest due to their cholesterol reducing properties.
Alignan, Marion +5 more
core +2 more sources
Highly sensitive analysis of sterol profiles in human serum by LC-ESI-MS/MSs⃞
Journal of Lipid Research, 2008 We have developed a highly sensitive and specific method for the analysis of serum sterol profiles. Sterols in 1 μl of dried serum were derivatized into picolinyl esters (3β-picolinate) and analyzed by liquid chromatography-tandem mass spectrometry (LC ...
Akira Honda +8 more
doaj +1 more source
Molecular Therapy: Methods & Clinical Development, 2021 Cerebrotendinous xanthomatosis (CTX) is an autosomal recessive disease caused by mutations in the CYP27A1 gene, encoding the sterol 27-hydroxylase. Disruption of the bile acid biosynthesis pathway and accumulation of toxic precursors such as cholestanol ...
Sara Lumbreras +12 more
doaj +1 more source