Results 51 to 60 of about 2,254 (206)
Moderately elevated levels of plasma plant sterols have been suspected to be causally involved in atherosclerosis. The aim of this study was to investigate whether plant sterols and other markers of sterol metabolism predicted all-cause and ...
Guenther Silbernagel +6 more
doaj +1 more source
ABSTRACT Geochemical data compiled from dried sediments from three water reservoirs at the ancient Maya city of Ucanal, Petén, Guatemala, reveal low to undetectable fecal biomarker concentrations. These low concentrations may be the result of the aerobic decay of sterols combined with well‐managed waste disposal practices.
Jean D. Tremblay +3 more
wiley +1 more source
The concentrations of serum cholesterol, cholestanol and non-cholesterol sterols were measured in a patient with cerebrotendinous xanthomatosis under different therapeutic regimens.
DOTTI M. T. +3 more
core +1 more source
Highly sensitive analysis of sterol profiles in human serum by LC-ESI-MS/MSs⃞
We have developed a highly sensitive and specific method for the analysis of serum sterol profiles. Sterols in 1 μl of dried serum were derivatized into picolinyl esters (3β-picolinate) and analyzed by liquid chromatography-tandem mass spectrometry (LC ...
Akira Honda +8 more
doaj +1 more source
Two genes (choRI and choRII) encoding cholesterol oxidases belonging to the vanillyl-alcohol oxidase (VAO) family were cloned on the basis of putative cholesterol oxidase gene sequences in the genome sequence data of Rhodococcus erythropolis PR4.
Makoto Ishikawa, Noriyuki Doukyu
core +1 more source
Cerebrotendinous xanthomatosis (CTX) is a rare autosomal recessive disorder of bile acid biosynthesis. Clinically, CTX patients present with tendon xanthomas, juvenile cataracts, and progressive neurological dysfunction and can be diagnosed by the ...
Mi-Hye Lee +7 more
doaj +1 more source
Synthesis of conjugated cholesterol and cholestanols.
The glucuronides, sulfates, glucosides and N-acetylglucosaminides of cholesterol and epimeric 5α-cholestan-3-ols have been synthesized. The formation of a β-glucoside linkage was readily achieved by means of the Koenigs-Knorr reaction with the corresponding α-acetohalosugar, employing cadmium carbonate as a catalyst.
GOTO, JUNICHI +2 more
openaire +1 more source
Phytochemicals in Asthma Management: Mechanism, Translational Gap and Clinical Integration
The phytochemicals including flavonoids, alkaloids, terpenoids, and saponins modulate inflammatory, oxidative, and immune pathways in asthma. It highlights their mechanisms of action, translational challenges, advanced formulation strategies, and emerging clinical potential as adjunct therapies for precision‐based asthma management.
Pulak Majumder, Trisita Majumder
wiley +1 more source
On the substrate specificity of human CYP27A1: implications for bile acid and cholestanol formation
The mitochondrial sterol 27-hydroxylase (CYP27A1) is required for degradation of the C27-sterol side chain in bile acid biosynthesis. CYP27A1 seems, however, to have roles beyond this, as illustrated by patients with a deficient sterol 27-hydroxylase due
Wikvall, Kjell, +3 more
core +1 more source
Case Report: Cerebrotendinous xanthomatosis
Cerebrotendinous xanthomatosis is a rare genetic disorder. We present and discuss the clinical, radiological, and histopathologic findings in a 36-year-old woman who had juvenile cataract, childhood diarrhea, mental retardation, cerebellar ataxia, and ...
Amit A Karandikar +3 more
doaj +1 more source

