Results 41 to 50 of about 2,254 (206)

Regression of plasma phytosterol levels normalized by 5-α-cholestanol on dietary phytosterol intake (DPI).

open access: yes, 2015
All values were transformed to natural log. Dotted lines represent 95% prediction limits of Ln(Campesterol/5-α-cholestanol) (A) and Ln(Total phytosterols/5-α-cholestanol) (B).
Richard E. Ostlund Jr (691232)   +5 more
core   +1 more source

Elevated serum squalene and cholesterol synthesis markers in pregnant obese women with gestational diabetes mellitus1

open access: yesJournal of Lipid Research, 2014
We examined serum cholesterol synthesis and absorption markers and their association with neonatal birth weight in obese pregnancies affected by gestational diabetes mellitus (GDM).
Helena E. Miettinen   +7 more
doaj   +1 more source

Gene supplementation of CYP27A1 in the liver restores bile acid metabolism in a mouse model of cerebrotendinous xanthomatosis

open access: yesMolecular Therapy: Methods & Clinical Development, 2021
Cerebrotendinous xanthomatosis (CTX) is an autosomal recessive disease caused by mutations in the CYP27A1 gene, encoding the sterol 27-hydroxylase. Disruption of the bile acid biosynthesis pathway and accumulation of toxic precursors such as cholestanol ...
Sara Lumbreras   +12 more
doaj   +1 more source

On the Conversion of Cholestanol into Allocholic Acid in Rat Liver [PDF]

open access: yesEuropean Journal of Biochemistry, 1971
The early steps in the conversion of cholestanol into allocholic acid were studied in homogenates of rat liver. The 20000 ×g supernatant fluid was found to catalyze 7α‐hydroxylation of cholestanol. Under the same conditions 7α‐hydroxylation of 5α‐cholestan‐3α‐ol and 5α‐cholestan‐3‐one was insignificant.
I, Björkhem, J, Gustafsson
openaire   +2 more sources

Methylation of the Fourth Position of Cholestanol Is Not Required for Dauer Larva Formation

open access: yes, 2013
Structural formulae and space-filling models of (A) cholestanol, (B) lophanol, and (C) 4αF-cholestanol. Abilities to support reproductive growth or dauer formation in the second generation are indicated. R, reproduction; D, dauer larva.
Hans-Joachim Knölker (56897)   +8 more
core   +1 more source

Inheritance of cholesterol metabolism of probands with high or low cholesterol absorption

open access: yesJournal of Lipid Research, 2002
Heredity of cholesterol absorption and synthesis was studied in siblings of hypercholesterolemic probands with low and high serum cholestanol to cholesterol ratio (assumed to indicate low and high absorption of cholesterol, respectively).
Helena Gylling, Tatu A. Miettinen
doaj   +1 more source

Insulin resistance is associated with increased cholesterol synthesis and decreased cholesterol absorption in normoglycemic men

open access: yesJournal of Lipid Research, 2004
Type 2 diabetes has been associated with high synthesis and low absorption of cholesterol independent of weight, indicating that insulin resistance may be a link between glucose and cholesterol metabolism.
Jussi Pihlajamäki   +3 more
doaj   +1 more source

Cobalt‐Catalyzed Radical Ligand Transfer (RLT) Enables Remote‐Markovnikov Hydroamination of Alkenes

open access: yesAngewandte Chemie International Edition, EarlyView.
A cobalt‐catalyzed remote‐Markovnikov 1,3‐hydroamination of allyl carboxylates proceeds through MHAT, 1,2‐radical acyloxy migration (1,2‐RAM), and radical ligand transfer (RLT) from a Co‐N intermediate, providing protected amino alcohols. ABSTRACT Amino alcohols are prevalent in pharmaceuticals, agrochemicals, and functional materials, yet ...
Arman Khosravi   +7 more
wiley   +1 more source

Serum Phytosterols Are Not Associated with Inflammatory Markers in Two Cross-Sectional, Swiss Population-Based Studies (The CoLaus|PsyCoLaus Study)

open access: yes, 2022
Background: The association between inflammation and dietary sterols remains poorly assessed at the population level. Aims: To assess the possible association between serum levels of various phytosterols (PS) and inflammatory markers.
Marques-Vidal, Pedro   +5 more
core   +1 more source

Iminodirhodium‐ and Iminocopper‐Catalyzed CH Activation: Chemoselective Oxidation of Alcohols and Aldehydes via Intermolecular Hydride Abstraction

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
Chemoselective hydride abstractor iminometalloids, derived from O‐mesylacetoxime (MAO) using Rh2(II/II) or Cu(I) catalysts, can activate the C–Hα bonds of alcohols and aldehydes ultimately forming ketones, carboxylic acids, and esters even in the presence of C–H bonds with comparable bond strengths.
Raghunath Reddy Anugu   +2 more
wiley   +1 more source

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