Results 71 to 80 of about 5,139 (246)

Insulin sensitivity regulates cholesterol metabolism to a greater extent than obesity: lessons from the METSIM Study1

open access: yesJournal of Lipid Research, 2010
Cholesterol synthesis is upregulated and absorption downregulated in insulin resistance and in type 2 dia-betes. We investigated whether alterations in cholesterol metabolism are observed across the glucose tolerance status, from normoglycemia through ...
Helena Gylling   +6 more
doaj   +1 more source

Sterol concentration and distribution in sunflower seeds (Helianthus annuus L.) during seed development [PDF]

open access: yes, 2010
Sunflower seeds are currently used for edible oil production. Among oil minor compounds, phytosterols are of special interest due to their cholesterol reducing properties.
Alignan, Marion   +5 more
core   +2 more sources

Cerebrotendinous xanthomatosis - A case report

open access: yesIndian Journal of Radiology and Imaging, 2019
Cerebrotendinous xanthomatosis (CTX) is a rare autosomal recessive disorder resulting from a defective enzyme in bile acid synthesis pathway leading to neurological, ocular, vascular, and musculoskeletal symptoms from deposition of cholestanol and ...
Arshed Hussain Parry   +3 more
doaj   +1 more source

Elevated serum squalene and cholesterol synthesis markers in pregnant obese women with gestational diabetes mellitus1

open access: yesJournal of Lipid Research, 2014
We examined serum cholesterol synthesis and absorption markers and their association with neonatal birth weight in obese pregnancies affected by gestational diabetes mellitus (GDM).
Helena E. Miettinen   +7 more
doaj   +1 more source

Inheritance of cholesterol metabolism of probands with high or low cholesterol absorption

open access: yesJournal of Lipid Research, 2002
Heredity of cholesterol absorption and synthesis was studied in siblings of hypercholesterolemic probands with low and high serum cholestanol to cholesterol ratio (assumed to indicate low and high absorption of cholesterol, respectively).
Helena Gylling, Tatu A. Miettinen
doaj   +1 more source

Mass spectrometric analysis of epimeric 3α/3β functionalized steroids. [PDF]

open access: yes, 2007
Tandem mass spectrometry (MS/MS) using an atmospheric pressure chemical ionization (APCI) source in positive mode (+) reveals different intensity ratios of two fragment peaks of the epimeric cholestane derivatives synthesized from 3{460}- or 3β ...
Almeida, Paulo   +5 more
core   +1 more source

Insulin resistance is associated with increased cholesterol synthesis and decreased cholesterol absorption in normoglycemic men

open access: yesJournal of Lipid Research, 2004
Type 2 diabetes has been associated with high synthesis and low absorption of cholesterol independent of weight, indicating that insulin resistance may be a link between glucose and cholesterol metabolism.
Jussi Pihlajamäki   +3 more
doaj   +1 more source

Genetic engineering and molecular characterization of yeast strain expressing hybrid human-yeast squalene synthase as a tool for anti-cholesterol drug assessment [PDF]

open access: yes, 2016
AIMS: The main objective of the study is molecular and biological characterization of the human-yeast hybrid squalene synthase (SQS), as a promising target for treatment of hypercholesterolaemia.
Burzynska, Beata   +12 more
core   +1 more source

Determination of Sterol and Fatty Acid Compositions, Oxidative Stability, and Nutritional Value of Six Walnut (Juglans regia L.) Cultivars Grown in Portugal [PDF]

open access: yes, 2003
Six cultivars (Franquette, Marbot, Mayette, Mellanaise, Lara, and Parisienne) of walnuts (Juglans regia L.) were collected during the 2001 crop, from Bragança, Portugal.
Amaral, Joana S.   +4 more
core   +1 more source

The associations of cholesterol metabolism and plasma plant sterols with all-cause and cardiovascular mortality[S]

open access: yesJournal of Lipid Research, 2010
Moderately elevated levels of plasma plant sterols have been suspected to be causally involved in atherosclerosis. The aim of this study was to investigate whether plant sterols and other markers of sterol metabolism predicted all-cause and ...
Guenther Silbernagel   +6 more
doaj   +1 more source

Home - About - Disclaimer - Privacy