Results 81 to 90 of about 27,709 (227)

Adverse Pregnancy Outcomes and Prognostic Factors in Hepatitis B Virus Patients with Intrahepatic Cholestasis During Pregnancy

open access: yesClinical and Experimental Obstetrics & Gynecology
Background: We conducted this study to investigate adverse pregnancy outcomes of hepatitis B virus infection coexistng with intrahepatic cholestasis in pregnant women, along with identifying associated risk factors.
Chong Zhang   +3 more
doaj   +1 more source

Indocyanine Green Clearance Correlates With Biomarkers Reflecting Key Disease‐Driving Mechanisms in Advanced Chronic Liver Disease and Predicts Acute‐on‐Chronic Liver Failure and Death

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
Indocyanine green clearance by pulse dye densitometry correlates with portal hypertension, systemic inflammation and circulatory dysfunction in advanced chronic liver disease. While diagnostic accuracy for CSPH was limited, ICG‐R15 independently predicted decompensation and ACLF/liver‐related mortality, highlighting its prognostic value across disease ...
Mathias Jachs   +17 more
wiley   +1 more source

Cholestasis in Chronic Liver Disease and the Role of Ademetionine in its Treatment (Literature Review and Expert Panel Resolution)

open access: yesРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии
Aim: to analyse the principles of diagnosis and treatment of intrahepatic cholestasis in chronic liver diseases, to present data on the effectiveness of ademetionine in the treatment of chronic liver diseases with intrahepatic cholestasis and the ...
K. L. Raikhelson   +6 more
doaj   +1 more source

Characterisation and Prognostic Implication of Cholestasis After Burn Injury

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
In 532 burn ICU patients, we quantified trajectories of cholestasis markers and validated burn‐associated cholestasis definitions. Bilirubin dynamics, particularly hyperbilirubinemia ≥ 2× ULN within 14 days, independently predicted excess in‐hospital and overall mortality beyond burn and critical‐illness severity, identifying a high‐risk subgroup after
Lorenz Semmler   +16 more
wiley   +1 more source

Liver transplantation for arteriohepatic dysplasia (Alagille's syndrome) [PDF]

open access: yes, 1992
Thirteen out of 268 children (
Borland, L   +9 more
core   +1 more source

Genetic Cholestasis: Lessons from the Molecular Physiology of Bile Formation

open access: yesCanadian Journal of Gastroenterology, 2000
Progressive familial intrahepatic cholestasis (PFIC) is a group of severe genetic cholestatic liver diseases of early life. PFIC types 1 and 2 are characterized by cholestasis and a low to normal serum gamma-glutamyltransferase (GGT) activity, whereas in
Peter LM Jansen, Michael Müller
doaj   +1 more source

Innovations in Simulation: Scaffolding a Triage Experience

open access: yesJournal of Midwifery &Women's Health, EarlyView.
Abstract Certified midwives, certified nurse‐midwives, and women's health nurse practitioners (WHNPs) play a vital role in triaging pregnant patients in the ambulatory and inpatient settings. Demonstrating proficiency with this skill set requires time and experience.
Kathryn McDevitt   +4 more
wiley   +1 more source

Genetic variants associated with gastrointestinal symptoms in Fabry disease. [PDF]

open access: yes, 2016
Gastrointestinal symptoms (GIS) are often among the earliest presenting events in Fabry disease (FD), an X-linked lysosomal disorder caused by the deficiency of α-galactosidase A.
Agapito, Giuseppe   +14 more
core   +1 more source

Red blood cell exchange followed by plasma exchange in patients with intrahepatic cholestasis due to sickle cell disease

open access: yesÇukurova Üniversitesi Tıp Fakültesi Dergisi, 2016
Intrahepatic cholestasis, a rare complication of sickle cell anemia, is characterized by marked hyperbilirubinemia, acute hepatic failure, and an often fatal course.
Nurhilal Buyukkurt   +4 more
doaj   +1 more source

A review of xenobiotic membrane transporter expression within the human placenta: Lessons gained from primary tissue and in vitro methodologies

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A summary of the current knowledge around membrane transporter expression in the most widely used in vitro models of human trophoblasts, including primary placental tissue, cancer cell lines and trophoblast stem cells, as well as the techniques to attempt to mimic the human placenta in vivo.
Rhiannon Pass   +2 more
wiley   +1 more source

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