Results 91 to 100 of about 139,121 (234)

Intrahepatic Cholestasis [PDF]

BMJ, 1964
D F, ROBERTS, R E, TANNER
openaire   +2 more sources

Sepsis as a cause of intrahepatic cholestasis [PDF]

, 2009
Introduction. The causes of intrahepatic cholestasis include cholestatic viral hepatitis, primary biliary cirrhosis, benign recurrent cholestasis, primary sclerosing cholangitis and sepsis.
Ćulafić Đorđe, Ješić Rada, Cvejić Tatjana, Šarenac-Kovač Radmila, Bulat Vladislava, Rudić Jelena   +5 more
core   +1 more source

Genetic Cholestasis: Lessons from the Molecular Physiology of Bile Formation

Canadian Journal of Gastroenterology, 2000
Progressive familial intrahepatic cholestasis (PFIC) is a group of severe genetic cholestatic liver diseases of early life. PFIC types 1 and 2 are characterized by cholestasis and a low to normal serum gamma-glutamyltransferase (GGT) activity, whereas in
Peter LM Jansen, Michael Müller
doaj   +1 more source

Red blood cell exchange followed by plasma exchange in patients with intrahepatic cholestasis due to sickle cell disease

Çukurova Üniversitesi Tıp Fakültesi Dergisi, 2016
Intrahepatic cholestasis, a rare complication of sickle cell anemia, is characterized by marked hyperbilirubinemia, acute hepatic failure, and an often fatal course.
Nurhilal Buyukkurt, ilknur Kozanoglu, Can Boga, Hakan Ozdogu, Mahmut Yeral   +4 more
doaj   +1 more source

Transcriptional regulation of hepatobiliary transport systems in health and disease: Implications for a rationale approach to the treatment of intrahepatic cholestasis

Annals of Hepatology, 2005
Hepatobiliary transport systems mediate hepatic uptake and biliary excretion of bile acids, bilirubin and other biliary constituents. Hereditary or acquired defects of these transporters may cause or maintain cholestasis and jaundice under various ...
Martin Wagner, Michael Trauner
doaj   +1 more source

Ursodeoxycholic acid versus placebo in women with intrahepatic cholestasis of pregnancy (PITCHES): a randomised controlled trial

The Lancet, 2019
Summary Background Intrahepatic cholestasis of pregnancy, characterised by maternal pruritus and increased serum bile acid concentrations, is associated with increased rates of stillbirth, preterm birth, and neonatal unit admission.
L. Chappell, Jennifer L. Bell, Anne Smith, L. Linsell, E. Juszczak, P. Dixon, J. Chambers, R. Hunter, J. Dorling, C. Williamson, J. Thornton, I. Ahmed, R. Arya, V. Beckett, A. Bhide, H. Brown, G. Bugg, H. Cameron, N. Deole, M. Dey, J. Dwyer, L. Fahel, R. Gada, J. Girling, A. Haestier, S. Hughes, R. Indusekhar, B. Jones, R. Khan, A. Kirkpatrick, E. Knox, K. Lincoln, M. Macdougall, F. Majoko, K. Mcintyre, M. Noori, W. Oakley, Jane Preston, P. Ranka, M. Rashid, M. Salloum, M. Samyraju, C. Schram, S. Sen, S. Stone, B. Tan   +45 more
semanticscholar   +1 more source

INTRAHEPATIC CHOLESTASIS OF PREGNANCY: THREE NOVEL MDR3 GENE MUTATIONS

, 2006
The aetiology of intrahepatic cholestasis of pregnancy is unknown, but more than 10 different MDR3 gene mutations have recently been identified.To evaluate the genetic contribution of the MDR3 gene in the pathogenesis of intrahepatic cholestasis of ...
ESPOSITO W, BRAGHIN C, CALDERI I., SOARDO G, MAZZELLA G., VARIOLA A., PATERNOSTER D., FLOREANI, ANNAROSA, TOMMASI A. M., MARCHESONI D, TOMMASI A. M, AZZAROLI F., BRAGHIN C., CARDERI, ISABELLA, VARIOLA A, ESPOSITO W., FLOREANI A., MARCHESONI, Diego, PATERNOSTER D, AZZAROLI F, SOARDO G.   +20 more
core   +1 more source

Genome-wide meta-analysis identifies genetic drivers of bile acid metabolism in intrahepatic cholestasis of pregnancy

Nature Communications
Intrahepatic cholestasis of pregnancy, which affects 0.2–2% of pregnancies, is characterized by pruritus, increased aminotransferase activity and elevated serum bile acids. Previous studies have implicated liver-enriched genes in intrahepatic cholestasis
Jaakko S. Tyrmi, Juha Karjalainen, Samvida S. Venkatesh, Clara Benoit-Pilven, Susanna M. Lemmelä, Søren Brunak, Bitten Aagaard, Mie T. Bruun, Christian Erikstrup, Henrik Ullum, Ole B. Pedersen, Karina Banasik, Erik Sørensen, Christina Mikkelsen, Michael Schwinn, Arni Sturluson, Sisse R. Ostrowski, FinnGen, Estonian Biobank research team, DBDS Genomic Consortium, Johannes Kettunen, Henriette Svarre Nielsen, Mette Nyegaard, David Westergaard, Thorunn Rafnar, Patrick Sulem, Kari Stefansson, Priit Palta, Triin Laisk, Taru Tukiainen, Cecilia M. Lindgren, Mark Daly, Aki S. Havulinna, Hannele M. Laivuori   +33 more
doaj   +1 more source

The impact of intrahepatic cholestasis of pregnancy with hepatitis B virus infection on perinatal outcomes

, 2014
Yun Hu, Yi-Ling Ding, Ling Yu Department of Obstetrics and Gynecology, The Second Xiangya Hospital, Central South University, Changsha, Hunan Province, People's Republic of China Introduction: To investigate the impact of intrahepatic cholestasis of
Yu L, Hu Y, Ding YL
core  

Post-liver transplant intrahepatic cholestasis : etiology, clinical presentation, therapy [PDF]

, 2017
Post-liver transplant intrahepatic cholestasis is consequent to the impairment of bile flow or formation. It may develop in the early (within 6 months) or in the late (more than 6 months) post-liver transplant period and different causes may be ...
V.M. Mazzaferro, A. Gasbarrini, M. Biolato, S. Bhoori, G. Marrone, A. Grieco, M. Pompili, M. A. Zocco, F. R. Ponziani   +8 more
core   +2 more sources