Results 101 to 110 of about 878,930 (205)

High-density lipoprotein metabolism and reverse cholesterol transport: strategies for raising HDL cholesterol

Anatolian journal of cardiology, 2017
A key to effective treatment of cardiovascular disease is to understand the body’s complex lipoprotein transport system. Reverse cholesterol transport (RCT) is the process of cholesterol movement from the extrahepatic tissues back to the liver ...
K. Trajkovska, S. Topuzovska
semanticscholar   +1 more source

J-Shaped Association Between Non-HDL Cholesterol to HDL Cholesterol Ratios and Gout in US Adults With Gout

Journal of Multidisciplinary Healthcare
Ruo-Nan Tian,1,2 Sheng-Xiao Zhang,2– 5 Nan Zhang,6 Yan Shi,1 Hua-Qing Guo,1 Chen Wang,1 Zhi-Guang Duan6 1College of Humanities and Social Sciences, Shanxi Medical University, Taiyuan, Shanxi, 030001, People’s Republic of China; 2Key Laboratory of ...
Tian RN, Zhang SX, Zhang N, Shi Y, Guo HQ, Wang C, Duan ZG   +6 more
doaj  

Thermogenic adipocytes promote HDL turnover and reverse cholesterol transport

Nature Communications, 2017
Brown and beige adipocytes combust nutrients for thermogenesis and through their metabolic activity decrease pro-atherogenic remnant lipoproteins in hyperlipidemic mice. However, whether the activation of thermogenic adipocytes affects the metabolism and
A. Bartelt, A. Bartelt, C. John, Nicola Schaltenberg, J. Berbée, A. Worthmann, M. Cherradi, C. Schlein, Julia Piepenburg, M. Boon, F. Rinninger, M. Heine, K. Toedter, A. Niemeier, S. Nilsson, S. Nilsson, Markus Fischer, S. Wijers, W. Lichtenbelt, L. Scheja, P. Rensen, J. Heeren   +21 more
semanticscholar   +1 more source

High density lipoproteins and reverse cholesterol transport [PDF]

, 1992
The e>:periments described in this thesis were performed in order to clarify the mechanism of efflux of cellular cholesterol, a key step in reverse cholesterol transport.
Kilsdonk, E.P.C. (Liesbeth)
core  

Effects of the SGLT2 inhibitor dapagliflozin on HDL cholesterol, particle size, and cholesterol efflux capacity in patients with type 2 diabetes: a randomized placebo-controlled trial

Cardiovascular Diabetology, 2017
BackgroundSodium-glucose co-transporter-2 inhibitors (SGLT2i) reduce glucose levels, body weight, and blood pressure, possibly resulting in cardiovascular protection. In phase III trials, SGLT2i were shown to increase HDL cholesterol.
G. Fadini, B. Bonora, G. Zatti, N. Vitturi, E. Iori, M. Marescotti, M. Albiero, A. Avogaro   +7 more
semanticscholar   +1 more source

High‐Density Lipoprotein Particle Concentration and Size Predict Incident Coronary Artery Disease Events in a Cohort With Type 1 Diabetes

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background The cholesterol efflux capacity of high density lipoprotein (HDL) is negatively associated with cardiovascular risk. Small HDL particles account almost quantitatively for cholesterol efflux capacity, perhaps mediated through efflux of ...
Tina Costacou, Tomas Vaisar, Rachel G. Miller, W. Sean Davidson, Jay W. Heinecke, Trevor J. Orchard, Karin E. Bornfeldt   +6 more
doaj   +1 more source

Powerful genome-wide design and robust statistical inference in two-sample summary-data Mendelian randomization [PDF]

arXiv, 2018
Two-sample summary-data Mendelian randomization (MR) has become a popular research design to estimate the causal effect of risk exposures. With the sample size of GWAS continuing to increase, it is now possible to utilize genetic instruments that are only weakly associated with the exposure.
arxiv  

Cholesterol transport between cells and high density lipoprotein subfractions from obese and lean subjects

Journal of Lipid Research, 1998
We studied the pathway of cholesterol efflux from fibroblasts by testing plasma samples from obese and lean subjects. Plasma samples were incubated with [3H]cholesterol-labeled human skin fibroblasts for 1 h to ensure uniform labeling of all of the high ...
Takayuki Sasahara, Paul Nestel, Noel Fidge, Dmitri Sviridov   +3 more
doaj  

Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity. [PDF]

, 2019
Many genetic loci affect circulating lipid levels, but it remains unknown whether lifestyle factors, such as physical activity, modify these genetic effects.
Alver, Maris, Amin, Najaf, Amini, Marzyeh, Arnett, Donna K, Aschard, Hugues, Aslibekyan, Stella, Bartz, Traci M, Bentley, Amy R, Bielak, Lawrence F, Boerwinkle, Eric, Boissel, Mathilde, Brown, Michael R, Brumat, Marco, Cade, Brian, Campbell, Archie, Canouil, Mickaël, Chai, Jin Fang, Chasman, Daniel I, Chen, Xu, Chen, Yii-Der Ida, Concas, Maria Pina, Connell, John, de Las Fuentes, Lisa, de Mutsert, Renée, de Silva, H Janaka, de Vries, Paul S, Demirkan, Ayşe, Ding, Jingzhong, Divers, Jasmin, Dorajoo, Rajkumar, Eaton, Charles B, Evangelou, Evangelos, Faul, Jessica D, Feitosa, Mary F, Fisher, Virginia, Franceschini, Nora, Friedlander, Yechiel, Gabriel, Kelley P, Gao, Chuan, Ghanbari, Mohsen, Giulianini, Franco, Graff, Mariaelisa, Gu, Chi Charles, Gu, Dongfeng, Guo, Xiuqing, Harris, Sarah E, Harris, Tamara B, Hartwig, Fernando P, He, Jiang, He, Meian, Heikkinen, Sami, Heng, Chew-Kiat, Horimoto, Andrea RVR, Hsu, Fang-Chi, Hunt, Steven C, Ikram, M Arfan, Jackson, Anne U, Jakupović, Hermina, Jonas, Jost B, Kho, Minjung, Kilpeläinen, Tuomas O, Koh, Woon-Puay, Komulainen, Pirjo, Kraja, Aldi T, Krieger, Jose E, Kühnel, Brigitte, Laguzzi, Federica, Li, Changwei, Li, Xiaoyin, Lohman, Kurt K, Lyytikäinen, Leo-Pekka, Manning, Alisa, Marten, Jonathan, Musani, Solomon K, Nolte, Ilja M, Noordam, Raymond, Ntalla, Ioanna, Rauramaa, Rainer, Riaz, Muhammad, Richard, Melissa, Robino, Antonietta, Rueedi, Rico, Schwander, Karen, Sim, Xueling, Smith, Albert V, Stringham, Heather M, Sung, Yun Ju, Tajuddin, Salman M, Takeuchi, Fumihiko, van der Most, Peter J, Varga, Tibor V, Verweij, Niek, Vojinovic, Dina, Wang, Heming, Wang, Zhe, Ware, Erin B, Wen, Wanqing, Winkler, Thomas W, Yanek, Lisa R, Zhao, Jing Hua   +99 more
core  

Lipid Abnormalities Associated With Stroke

Annals of Indian Academy of Neurology, 2005
Association of dyslipidemia with stroke is conflicting though recent studies point to their positive role. Sixty consecutive patients with stroke were analyzed for fasting lipid profile values.
Thacker Anup K, Saxena Shweta, Khan Juned, Saxena Sharda P   +3 more
doaj