Results 71 to 80 of about 927,420 (325)

Triglyceride to high-density lipoprotein cholesterol and low-density lipoprotein cholestrol to high-density lipoprotein cholesterol ratios are predictors of cardiovascular risk in Iranian adults: Evidence from a population-based cross-sectional study

Caspian Journal of Internal Medicine, 2020
Background: The superiority of TG/HDL-C and LDL-C/HDL-C ratios in predicting  CVD risk is a matter of debates. Thus, the objective of this study was to compare TG/HDL-C and LDL-C to HDL-C ratios in predicting the risk of CVD events.
Karimollah Hajian-Tilaki, Behzad Heidari, Afsaneh Bakhtiari   +2 more
doaj  

ApoA-I knockout mice: characterization of HDL metabolism in homozygotes and identification of a post-RNA mechanism of apoA-I up-regulation in heterozygotes

Journal of Lipid Research, 1997
The major high density lipoprotein (HDL) apolipoprotein, apoA-I, was knocked out by gene targeting in ES cells to provide a model for the study of HDL metabolism and its relationship to plasma and tissue cholesterol metabolism.
A S Plump, N Azrolan, H Odaka, L Wu, X Jiang, A Tall, S Eisenberg, J L Breslow   +7 more
doaj   +1 more source

Spirulina platensis effects on the levels of total cholesterol, HDL and triacylglycerols in rabbits fed with a hypercholesterolemic diet

, 2008
In this work, hypercholesterolemia was induced in rabbits by feeding them a high cholesterol diet (CD, 350 mg/d) and the effects of supplementing this diet with 0.5 g/d Spirulina platensis was evaluated by measuring the levels of serum total-cholesterol (
L. Colla, A. L. Muccillo-Baisch, J. Costa   +2 more
semanticscholar   +1 more source

Paradoxical mortality differential of HDL cholesterol

Asian Journal of Medical Sciences, 2023
High-density lipoprotein (HDL) cholesterol has been known for ages to be cardio-protective due to its defensive action against genesis of atherosclerosis.
Jyotishman Mukhopadhyay , Debayan Mallik , Sughandha Garg   +2 more
doaj   +1 more source

Postoperative Stress Accelerates Atherosclerosis Through Inflammatory Remodeling of the HDL Proteome and Impaired Reverse Cholesterol Transport

Advanced Science, EarlyView.
The study shows that noncardiac surgical inflammation rapidly disrupts HDL function and cholesterol efflux in mice and human patients. Impaired reverse cholesterol transport after surgery drives rapid lipid accumulation, NETosis, and apoptosis within atherosclerotic plaques.
Dominique M. Boucher, Victoria Lorant, Valerie Rochon, Abigail Carter, Cameron Stotts, My‐Anh Nguyen, Thomas Laval, Christina Emerton, Nathan Joyce, Nysa Vinayak, Marlena Scaffidi, David Cook, Katey J. Rayner, Rebecca C. Auer, Scott M. Gordon, Mireille I. Ouimet   +15 more
wiley   +1 more source

HUBUNGAN ANTARA AKTIVITAS FISIK DAN ANGKA KECUKUPAN GIZI MAKRONUTRIEN TERHADAP RASIO KOLESTEROL TOTAL/HDL PADA MASYARAKAT PEDESAAN

Jurnal Farmasi Sains dan Komunitas, 2017
Cardiovascular disease is the number one cause of death in the world. The diseaseis influenced by several factors such as lack of physical activity, imbalanced nutritional intake, and high blood cholesterol levels.
Utari Febrina Supomo Sunu, Galih Permadi, Fenty Fenty   +2 more
doaj   +1 more source

Fibrates Inhibit PLTP‐induced M2 Macrophage Infiltration and Increase the Sensitivity of Hepatocellular Carcinoma to ICIs

Advanced Science, EarlyView.
Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang, Yaning Li, Jianxun Cai, Lisi Luo, Pengfei Yang, Yutong Chen, Jiancong Zhou, Yan Zeng, Jiaping Yu, Weiyu Zhang, Wenzheng Pang, Yufang Li, Chunhua Wen, Jian Li, Linjuan Zeng   +14 more
wiley   +1 more source

Zinc Finger Protein 202, genetic variation, and HDL cholesterol in the general population

Journal of Lipid Research, 2006
Zinc Finger Protein 202 (ZNF202) is a transcriptional repressor that binds elements found predominantly in genes involved in HDL metabolism. We tested the following hypotheses: 1) frequencies of single-nucleotide polymorphisms (SNPs) and haplotypes in ...
Maria C. Stene, Ruth Frikke-Schmidt, Børge G. Nordestgaard, Anne Tybjærg-Hansen   +3 more
doaj   +1 more source

Total cholesterol/HDL cholesterol ratio and monocyte/HDL cholesterol ratio are related with subclinical hypothyroidism in polycystic ovary syndrome

Türk Biyokimya Dergisi, 2021
There is an association between serum thyrotropin (TSH) and lipid profile. However, there is a little information regarding the relation between subclinical hypothyroidism (SCH), atherogenic indices and inflammation in polycystic ovary syndrome (PCOS ...
Cakir Isil, Simsek Yasin
doaj   +1 more source

Lipid profile, cardiovascular disease and mortality in a Mediterranean high-risk population: The ESCARVAL-RISK study [PDF]

, 2017
Introduction The potential impact of targeting different components of an adverse lipid profile in populations with multiple cardiovascular risk factors is not completely clear.
Ascaso, Juan F, Bertomeu-González, Vicente, Bertomeu-Martínez, Vicente, Carmena, Rafael, Carratala-Munuera, Concepcion, Castellano, José M., Cooper, Richard, Cordero, Alberto, Durazo-Arvizu, Ramon, ESCARVAL Study Group, Fernández Giménez, Antonio, Gil-Guillén, Vicente F, Martin-Moreno, Jose M., Navarro Pérez, Jorge, Orozco Beltrán, Domingo, Pallarés-Carratalá, Vicente, Pascual de la Torre, Manuel, Pita Fernández, Salvador, Pérez Navarro, Ana M., Redón, Josep, Sanchis-Domenech, Carlos, Sanz, Ginés, Tellez-Plaza, Maria, Trillo, José L., Usó, Ruth, Valls Roca, Francisco   +25 more
core   +6 more sources