Results 71 to 80 of about 878,930 (205)
HDL and Reverse Cholesterol Transport.
Circulation Research, 2019 Cardiovascular disease, with atherosclerosis as the major underlying factor, remains the leading cause of death worldwide. It is well established that cholesterol ester-enriched foam cells are the hallmark of atherosclerotic plaques.
M. Ouimet, Tessa J. Barrett, E. Fisher
semanticscholar +1 more source
On the first bifurcation point for a free boundary problem modeling small arterial plaque [PDF]
arXiv, 2020 Atherosclerosis occurs when plaque clogs the arteries. It is a leading cause of death in the United States and worldwide. In this paper, we study the bifurcation for a highly nonlinear and highly coupled PDE model of plaque formation in the early stage of atherosclerosis.
arxiv
Unresolved excess accumulation of myelin-derived cholesterol contributes to scar formation after spinal cord injury [PDF]
arXiv, 2022 Background: Spinal cord injury triggers complex pathological cascades, resulting in destructive tissue damage and incomplete tissue repair. Scar formation is generally considered as a barrier for regeneration in central nervous system (CNS), while the intrinsic mechanism of scar-forming after spinal cord injury has not been completed deciphered ...
arxiv
American Journal of Clinical Nutrition, 2003 BACKGROUND The effects of dietary fats on the risk of coronary artery disease (CAD) have traditionally been estimated from their effects on LDL cholesterol.
R. Mensink, P. Zock, A. Kester, M. Katan
semanticscholar +1 more source
Prevalence of metabolic syndrome in baluch women in Chabahar [PDF]
, 2015 Epidemiological studies have shown the importance of the metabolic syndrome. With estimation of the metabolic syndrome, it may predict cardiovascular disease, sudden death and the presence of some other cardiovascular risk factors.
Majidi, F. +4 more
core +1 more source
Mendelian Randomization when Many Instruments are Invalid: Hierarchical Empirical Bayes Estimation [PDF]
arXiv, 2017 Estimating the causal effect of an exposure on an outcome is an important task in many economical and biological studies. Mendelian randomization, in particular, uses genetic variants as instruments to estimate causal effects in epidemiological studies.
arxiv
European Journal of Preventive Cardiology, 2019 Background Low concentrations of high-density lipoprotein cholesterol (HDL-C) represent a well-established cardiovascular risk factor. Paradoxically, extremely high HDL-C levels are equally associated with elevated cardiovascular risk, resulting in the U-
Ma Feng +24 more
semanticscholar +1 more source
Loci controlling plasma non-HDL and HDL cholesterol levels in a C57BL /6J × CASA /Rk intercross
Journal of Lipid Research, 2003 Plasma non-HDL and HDL cholesterol levels are predictors of cardiovascular diseases. We carried out a genetic cross between two laboratory inbred mouse strains, C57BL/6J and CASA/Rk, to detect loci that control the plasma levels of non-HDL and HDL ...
Ephraim Sehayek +4 more
doaj
Raft-like domain formation in model lipid-cholesterol aggregation [PDF]
arXiv, 2020 To understand mechanism of cell-membrane compartmentalization, we studied coarse-grained model systems consisting of lipid and cholesterol molecules. Cholesterol plays crucial role in lateral phase segregation in the bilayered lipid membrane to form cholesterol rich liquid ordered domains, termed as `rafts'.
arxiv
Plasma proteome correlates of lipid and lipoprotein: biomarkers of metabolic diversity and inflammation in children of rural Nepal. [PDF]
, 2019 Proteins involved in lipoprotein metabolism can modulate cardiovascular health. While often measured to assess adult metabolic diseases, little is known about the proteomes of lipoproteins and their relation to metabolic dysregulation and underlying ...
Christian, Parul +9 more
core