Results 71 to 80 of about 392,380 (285)

In Situ Lipoprotein‐seeking Dye for in Vivo Real‐Time Imaging of Lipid Dysregulation Diseases

open access: yesAdvanced Science, EarlyView.
This study develops lipoprotein‐seeking NIR‐II dyes that specifically bind circulating lipoproteins. These dyes form ultra‐stable complexes with endogenous lipoprotein, enabling real‐time, high‐contrast imaging of fatty liver and atherosclerotic plaques. Tunable binding kinetics allow customized imaging windows.
Yijing Du   +6 more
wiley   +1 more source

HUBUNGAN ANTARA AKTIVITAS FISIK DAN ANGKA KECUKUPAN GIZI MAKRONUTRIEN TERHADAP RASIO KOLESTEROL TOTAL/HDL PADA MASYARAKAT PEDESAAN

open access: yesJurnal Farmasi Sains dan Komunitas, 2017
Cardiovascular disease is the number one cause of death in the world. The diseaseis influenced by several factors such as lack of physical activity, imbalanced nutritional intake, and high blood cholesterol levels.
Utari Febrina Supomo Sunu   +2 more
doaj   +1 more source

Bolstering cholesteryl ester hydrolysis in liver: A hepatocyte-targeting gene delivery strategy for potential alleviation of atherosclerosis [PDF]

open access: yes, 2017
Current atherosclerosis treatment strategies primarily focus on limiting further cholesteryl esters (CE) accumulation by reducing endogenous synthesis of cholesterol in the liver.
Ghosh, Shobha   +5 more
core   +2 more sources

SR‐B1‐Mediated Transplacental Transfer of Hydrophobic Toxicants Disrupts Fetal Development During Barriergenesis

open access: yesAdvanced Science, EarlyView.
This study maps the spatiotemporal distribution of hydrophobic toxicants and endogenous metabolites in the developing placenta and fetus. By integrating mass spectrometry imaging with snRNA‐seq, we identify SR‐B1 as a key transporter driving early‐gestation xenobiotic transfer and reveal a critical exposure window associated with persistent fetal ...
Yixuan Huang   +10 more
wiley   +1 more source

Replacement of dietary saturated fatty acids by trans fatty acids lowers serum HDL cholesterol and impairs endothelial function in healthy men and women [PDF]

open access: yes, 2001
We tested whether trans fatty acids and saturated fatty acids had different effects on flow-mediated vasodilation (FMD), a risk marker of coronary heart disease (CHD). Consumption of trans fatty acids is related to increased risk of CHD, probably through
Bots, M.L., Katan, M.B., Roos, N.M., de
core   +2 more sources

4‐Hydroxybenzyl Alcohol Mitigates Hyperlipidemia‐Associated Depression by Inhibiting Neuroinflammation via the NKIRAS2/NF‐κB Pathway

open access: yesAdvanced Science, EarlyView.
4‐HBA upregulates NKIRAS2 levels, inhibiting the activation of the NF‐κB pathway and subsequently reducing the levels of neuroinflammatory markers. This modulation helps restore normal mood and behavior in hyperlipidemic conditions, providing a potential therapeutic strategy for managing hyperlipidemia‐associated depression.
Ying Zhang   +7 more
wiley   +1 more source

The Effects of Temulawak extract and Yoghurt on HDL-LDL mice blood exposed waste cooking oil [PDF]

open access: yes, 2015
Using cooking oil repeatedly in processing the fried foods can cause health problems, especially cholesterol metabolism that affect levels of HDL, LDL, triglycerides and total cholesterol blood that can cause blockage of blood vessels leading
Alipin, Kartiawati   +2 more
core  

Coronary heart disease risks associated with high levels of HDL cholesterol. [PDF]

open access: yes, 2014
BackgroundThe association between high-density lipoprotein cholesterol (HDL-C) and coronary heart disease (CHD) events is not well described in individuals with very high levels of HDL-C (>80 mg/dL).Methods and resultsUsing pooled data from 6 ...
Criqui, Michael H   +6 more
core   +2 more sources

Adhesion‐Related Macrophages Regulate Metabolic Homeostasis Through CAV‐1 Dependency

open access: yesAdvanced Science, EarlyView.
Adipose tissue harbors a distinct macrophage subpopulation, termed adhesion‐related macrophages (ARMs), which stably adhere to adipocytes. In obesity, ARMs represent the major expanding macrophage subset. They acquire material from adipocytes and rely on Caveolin‐1 for sustained lipid handling.
Wanyu Hu   +23 more
wiley   +1 more source

Total cholesterol/HDL cholesterol ratio and monocyte/HDL cholesterol ratio are related with subclinical hypothyroidism in polycystic ovary syndrome

open access: yesTürk Biyokimya Dergisi, 2021
There is an association between serum thyrotropin (TSH) and lipid profile. However, there is a little information regarding the relation between subclinical hypothyroidism (SCH), atherogenic indices and inflammation in polycystic ovary syndrome (PCOS ...
Cakir Isil, Simsek Yasin
doaj   +1 more source

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