Results 151 to 160 of about 381,129 (289)

Childhood Obesity and Familial Hypercholesterolemia: Genetic Diseases that Contribute to Cardiovascular Disease [PDF]

open access: yes, 2014
Childhood obesity occurs as the result of an imbalance between caloric intake and energy expenditure. Genetic risk factors for obesity have become an area of research due to its permanency.
Caudle, Alyssa
core   +1 more source

Immune Checkpoint Inhibitors and Cardiovascular Adverse Events

open access: yesESC Heart Failure, EarlyView.
Abstract In the last years, we assisted to a tremendous increase in therapeutic options for the management of cancers, with immunotherapy at the forefront of this innovation. Immune checkpoint inhibitors (ICIs) have been developed to enhance the activity of the immune system against cancer cells (1) and the number of approvals for ICIs has rapidly ...
Maria Luisa De Perna   +4 more
wiley   +1 more source

Effects of lipoprotein lipase and statins on cholesterol uptake into heart and skeletal muscles⃞

open access: yesJournal of Lipid Research, 2007
Regulation of cholesterol metabolism in cultured cells and in the liver is dependent on actions of the LDL receptor. However, nonhepatic tissues have multiple pathways of cholesterol uptake.
Masayoshi Yokoyama   +11 more
doaj  

BUN‐to‐ALB ratio as an effective predictor of 30 day mortality in ADHF patients in eastern China

open access: yesESC Heart Failure, EarlyView.
Abstract Aims The blood urea nitrogen‐to‐albumin ratio (BAR) is considered a potential indicator for assessing the poor prognosis of heart failure (HF). However, its prognostic value for Chinese patients with acute decompensated HF (ADHF) remains unclear.
Xin Huang   +8 more
wiley   +1 more source

Effect of apolipoprotein E phenotype on diet-induced lowering of plasma low density lipoprotein cholesterol.

open access: yesJournal of Lipid Research, 1994
The National Cholesterol Education Program (NCEP) has recommended that dietary total fat, saturated fat, and cholesterol intake be reduced to < or = 30% of calories, < 10% of calories, and < 300 mg/day, respectively (Step 1 diet) in the general ...
J Lopez-Miranda   +6 more
doaj  

Dapagliflozin effect on functional mitral regurgitation and myocardial remodelling: The DEFORM trial

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Functional mitral regurgitation (FMR) is associated with adverse outcomes in patients with heart failure, and current guideline‐directed medical therapy (GDMT) offers limited efficacy in managing FMR. This study aims to evaluate the therapeutic impact of the sodium‐glucose cotransporter 2 inhibitor (SGLT2i) dapagliflozin in patients with ...
Zhuoshan Huang   +18 more
wiley   +1 more source

Rates of low density lipoprotein uptake and cholesterol synthesis are regulated independently in the liver.

open access: yesJournal of Lipid Research, 1985
The relationship between rates of hepatic sterol synthesis and rates of hepatic low density lipoprotein (LDL) uptake (clearance) was studied in animals with high (rats), low (female hamsters), and very low (male hamsters) basal rates of hepatic sterol ...
D K Spady, S D Turley, J M Dietschy
doaj  

Cellular itinerary of LDL cholesterol

open access: yesProceedings of the National Academy of Sciences, 2022
openaire   +2 more sources

Prognostic value of lipid parameters among patients with heart failure: A systematic review and meta‐analysis

open access: yesESC Heart Failure, EarlyView.
Abstract Aims We sought to evaluate the prognostic value of different lipid parameters in patients with heart failure (HF). Methods and Results Electronic databases including MEDLINE, Embase, CENTRAL, and Web of Science were searched to identify studies that reported the association of any of the four lipid parameters [total cholesterol (TC), high ...
Ahmed Sayed   +9 more
wiley   +1 more source

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