Results 201 to 210 of about 381,129 (289)

Age Estimation From Blood Test Results Using a Random Forest Model

Journal of Clinical Laboratory Analysis, EarlyView.
From the perspective of preventive medicine, it is essential to clarify the relationship between medical examination data and aging and health problems. We successfully and accurately estimated age from clinical examination data using a random forest model. Postmenopausal women tended to have higher age estimates than premenopausal women.
Satomi Kodera, Osamu Yokoi, Masaki Kaneko, Yuka Sato, Susumu Ito, Katsuhiko Hata   +5 more
wiley   +1 more source

Indication‐Specific Dosing and Dose‐Evaluation Strategies in New Indications for Non‐Oncology Monoclonal Antibodies

The Journal of Clinical Pharmacology, EarlyView.
Abstract Compared to traditional small molecule drugs, monoclonal antibodies (mAbs) often display more complex pharmacokinetic (PK) and pharmacodynamic (PD) properties that may be impacted by disease‐specific factors. For mAbs in non‐oncology indications, where the same drug might be used for conditions involving different organ systems and/or having ...
Sherouk M. Tawfik, Fei Tang
wiley   +1 more source

Pharmacokinetics and Safety of Fenofibrate in Participants with Mild Hepatic Impairment or with Advanced Fibrosis due to Metabolic‐Associated Fatty Liver Disease

The Journal of Clinical Pharmacology, EarlyView.
Abstract Fenofibrate is contraindicated in patients with advanced hepatic fibrosis due to limited clinical data. We evaluated the pharmacokinetics and safety of fenofibrate in participants with mild hepatic impairment (phase 1 study) or advanced fibrosis due to metabolic‐associated fatty liver disease (MAFLD; phase 2a study).
Islam R. Younis, Elijah J. Weber, Cara Nelson, Ann R. Qin, Timothy R. Watkins, Ahmed A. Othman   +5 more
wiley   +1 more source

Real-World Assessment of the Association Between PCSK9i Adherence and LDL Reduction and Variability in a Chinese Clinical Practice. [PDF]

Clin Epidemiol
Ye X, Zhang S, Zhong X, Li M, Liu M, Zhuang X, Liao X.   +6 more
europepmc   +1 more source

Effects of a two‐night hospitalization program as a specific health guidance on obesity and cardiovascular disease risk factors

Journal of General and Family Medicine, EarlyView.
Abstract Background To assess the effects of a two‐night hospitalization program conducted at our hospital as part of a domestic health guidance system. This program is designed for lifestyle modification within a health checkup framework for metabolic syndrome. Methods This is a single‐center, retrospective observational study. We reviewed the medical
Maki Okazaki, Takeshi Katsuki, Hideaki Kurata, Shinichi Tanaka, Hajime Tanaka, Toshihide Kawai   +5 more
wiley   +1 more source

Impact of serum lipids on prognosis in breast cancer patients: a systematic review and meta-analysis. [PDF]

World J Surg Oncol
Gao W, Yao Y, Gao Q, Zhao T, Li H.
europepmc   +1 more source

Mortality and cardiovascular disease after cholecystectomy in type 2 diabetes: A nationwide longitudinal cohort study

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
Abstract Background The long‐term effects of cholecystectomy on mortality and cardiovascular disease (CVD) in patients with diabetes have not been evaluated. In the present study, we investigated the longitudinal effects of cholecystectomy on mortality and CVD in a population‐based cohort with type 2 diabetes (T2D). Methods In total, 2 216 930 national
Han Na Jung, Ji Hye Heo, Eun Roh, Kyung‐Do Han, Jun Goo Kang, Seong Jin Lee, Sung‐Hee Ihm   +6 more
wiley   +1 more source

Decrease in low-density lipoprotein cholesterol is associated with an increased risk of mortality in patients with diabetes mellitus. [PDF]

Front Cardiovasc Med
Kim YG, Jeong JH, Han KD, Roh SY, Seo CO, Kim Y, Lee HS, Shim J, Kim YH, Choi JI.   +9 more
europepmc   +1 more source

Trends in resource utilization for new‐onset psychosis hospitalizations at children's hospitals

Journal of Hospital Medicine, EarlyView.
Abstract Background Children with new‐onset psychosis often require hospitalization for medical evaluation. Objectives The goal of this study was to assess variations in the management of children with new‐onset psychosis and characterize trends in resource utilization.
Ankita Gupta, Matt Hall, Benjamin Masserano, Averi Wilson, Katherine Johnson, Clifford Chen, Lasya Challa, Harita Katragadda, Vineeta Mittal   +8 more
wiley   +1 more source

Elevated remnant cholesterol and triglycerides are predictors of increased total mortality in a primary health care population of 327,347 patients. [PDF]

Lipids Health Dis
Engell AE, Bathum L, Siersma V, Andersen CL, Lind BS, Jørgensen HL.   +5 more
europepmc   +1 more source