Results 151 to 160 of about 165,122 (254)

Role of selenium in the pathophysiology of cardiorenal anaemia syndrome

ESC Heart Failure, Volume 12, Issue 2, Page 770-780, April 2025.
Abstract Chronic kidney disease (CKD) and cardiovascular disease (CVD) have multiple bidirectional mechanisms, and anaemia is one of the critical factors that are associated with the progression of the two disorders [referred to as cardiorenal anaemia syndrome (CRAS)].
Shigeyuki Arai, Minoru Yasukawa, Shigeru Shibata   +2 more
wiley   +1 more source

Intestinal alkaline phosphatase is a receptor for cholesterol-lowering pentapeptide IIAEK and regulates cholesterol homeostasis in mice. [PDF]

Sci Rep
Takeuchi A, Oda N, Takada K, Mori R, Aida T, Banno A, Ebihara A, Nagaoka S.   +7 more
europepmc   +1 more source

Growth differentiation factor‐15 and N‐terminal pro‐BNP in acute heart failure with preserved ejection fraction

ESC Heart Failure, Volume 12, Issue 2, Page 888-899, April 2025.
Abstract Aims Heart failure with preserved ejection fraction (HFpEF) continues to be an increasingly common health problem associated with a high mortality rate. Elevated levels of Growth differentiation factor‐15 (GDF15) and N‐terminal pro‐brain natriuretic peptide (NT‐proBNP) are reportedly associated with poor clinical outcomes in a broad range of ...
Yoichiro Otaki, Tetsu Watanabe, Mari Shimizu, Shingo Tachibana, Junya Sato, Yuta Kobayashi, Harutoshi Tamura, Shigehiko Kato, Satoshi Nishiyama, Hiroki Takahashi, Takanori Arimoto, Masafumi Watanabe   +11 more
wiley   +1 more source

Cholesterol and Cholesterol-Lowering Medications in COVID-19-An Unresolved Matter. [PDF]

Int J Mol Sci
Grewal T, Nguyen MKL, Buechler C.
europepmc   +1 more source

Connecting the dots: A narrative review of the relationship between heart failure and cognitive impairment

ESC Heart Failure, Volume 12, Issue 2, Page 1119-1131, April 2025.
Abstract Large clinical data underscore that heart failure is independently associated to an increased risk of negative cognitive outcome and dementia. Emerging evidence suggests that cerebral hypoperfusion, stemming from reduced cardiac output and vascular pathology, may contribute to the largely overlapping vascular dementia and Alzheimer's disease ...
Mauro Massussi, Maria Giulia Bellicini, Marianna Adamo, Andrea Pilotto, Marco Metra, Alessandro Padovani, Riccardo Proietti   +6 more
wiley   +1 more source

Computer-aided design enables repurposing of proprotein convertase subtilisin/kexin type 9 degrader from cholesterol-lowering to colon cancer therapy. [PDF]

Mol Biomed
Fan G, Zha J, Chen S, Cang P, Zhang Q, Yang J, Liu M.   +6 more
europepmc   +1 more source

Sustainable Iron Catalysis for Chemodivergent Oxidation of Lignin‐Based Vanillyl Alcohol: Selective Access to Vanillin and Vanillic Acid

European Journal of Organic Chemistry, EarlyView.
Green reaction media enable chemodivergent oxidation of vanillyl alcohol, selectively affording vanillin or its fully oxidized counterpart, vanillic acid. The use of an earth‐abundant, inexpensive, and nontoxic iron catalyst for the transformation of lignin‐derived alcohol to fine chemicals underscores the sustainability of the process. A low E‐factor (
Rasmiranjan Hota, Chinmaya Kumar Meher, Bidraha Bagh   +2 more
wiley   +1 more source

Extensive LDL-cholesterol lowering by PCSK9 inhibitor on the risk of venous thrombosis. [PDF]

Eur Heart J Cardiovasc Pharmacother
Goto S, Goto S.
europepmc   +1 more source

The association between Healthy Eating Index‐2020 and epilepsy: Insights based on NHANES from 2013 to 2018

Epileptic Disorders, EarlyView.
Abstract Background Epilepsy is a serious chronic brain disease. However, limited study is focused on the association between dietary pattern and epilepsy management. Hence, we aim to investigate the association between the Healthy Eating Index (HEI‐2020) and epilepsy odds.
Kun Yu, Yingxin Wang, Huaiqing Gao
wiley   +1 more source

3-(Hetarylthio)-1-Propynyl (Dimethylalkyl) Silanes as Selective Cholesterol Level Lowering Agents

Main Group Metal Chemistry, 2006
Abele, Edgars, Veveris, Maris, Abele, Ramona, Rubina, Kira, Arsenyan, Pavel, Meirena, Dainuvite   +5 more
doaj   +1 more source