Results 161 to 170 of about 165,122 (254)

Carotenoid Interactions with PCSK9: Exploring Novel Cholesterol-Lowering Strategies. [PDF]

Pharmaceuticals (Basel)
Medoro A, Scapagnini G, Brogi S, Jafar TH, Trung TT, Saso L, Davinelli S.   +6 more
europepmc   +1 more source

Serum methylmalonic acid levels and epilepsy prevalence: Association analysis, exploratory mediation, and clinical corroboration

Epileptic Disorders, EarlyView.
Abstract Objective This study aimed to investigate the association between methylmalonic acid (MMA) and epilepsy prevalence and to explore potential inflammatory and nutritional pathways underlying this association. Methods This study included adults aged ≥ 20 years from the National Health and Nutrition Examination Survey (NHANES) 2011–2014.
Ningyu Wei, Ning Huang, Haipeng Chen, Rui Tang, Yuan Cheng, Xiang Zhang   +5 more
wiley   +1 more source

Phytobacter sp. RSE02 is a rice seed endophytic plant probiotic bacterium with human probiotic features and cholesterol-lowering ability. [PDF]

Sci Rep
Jana SK, Bhattacharya R, Mukherjee S, Gupta S, Hui SP, Chattopadhyay A, Biswas SR, Mandal S.   +7 more
europepmc   +1 more source

Cardiovascular events and mortality in adults with late onset seizures: Focus on enzyme‐modulating antiseizure medications

Epilepsia, EarlyView.
Abstract Objective Using a Dutch insurance claims registry, we examine whether people with epilepsy have an increased risk of major ischemic cardiovascular events or death compared to people without epilepsy. We also assess whether this risk differs between users of enzyme‐modulating and non‐enzyme‐modulating antiseizure medications (ASMs).
Paola Vassallo, Nathan A. Shlobin, Mark R. Keezer, Roland D. Thijs, Ley Sander   +4 more
wiley   +1 more source

PCSK9 - A New and Potent Approach to Lowering Cholesterol

Oman Medical Journal, 2013
Thomas F. Whayne Jr.
doaj   +1 more source

Altered gene expression in the liver and small intestine of horses with equine neuroaxonal dystrophy

Equine Veterinary Journal, EarlyView.
Abstract Background Equine neuroaxonal dystrophy/degenerative myeloencephalopathy (eNAD/EDM) is the second most common diagnosis of spinal ataxia in horses in the United States. The disease develops due to a combination of vitamin E deficiency and an unknown genetic risk factor(s), and there currently is no effective treatment.
Stephanie Ryan, Blythe Durbin‐Johnson, Kevin Woolard, Andrew D. Miller, Carrie J. Finno   +4 more
wiley   +1 more source

Adherence to a Cholesterol-Lowering Diet and the Risk of Pancreatic Cancer: A Case-Control Study. [PDF]

Nutrients
Di Maso M, Augustin LSA, Jenkins DJA, Crispo A, Toffolutti F, Negri E, La Vecchia C, Ferraroni M, Polesel J.   +8 more
europepmc   +1 more source

Quadruplex Bioactive FAND for Treating Acute Liver Failure Induced by Acetaminophen or Hepatectomy

Exploration, EarlyView.
This work developed a bioactive quadruplex FANDHP@FuEVs with intrinsic inflammation‐targeting properties of M2‐EVs and MSC‐EVs, harnessing the synergistic biological activities by leveraging four natural active components—M2‐EVs, MSC‐EVs, HGF, and PPC—to deliver pleiotropic therapies, including antioxidant, anti‐inflammatory, pro‐regenerative, and M1 ...
Meng Sun, Fang Fang, Juan Liu, Yueyun Fan, Sa Wang, Chuang Zhang, Weiyu Li, Zhengyang Quan, Dongxu Zhao, Min Hu, Jinfeng Zhang   +10 more
wiley   +1 more source

Cholesterol-Lowering Activity of Lactiplantibacillus pentosus KS6I1 in High-Cholesterol Diet-Induced Hypercholesterolemic Mice. [PDF]

J Microbiol Biotechnol
Damodharan K, Palaniyandi SA, Yang SH, Balaji S.   +3 more
europepmc   +1 more source

Hepatic Mechanisms and Therapeutic Target Underpinning Hypercoagulation in Obesity: Insights From Genetic and Transcriptomic Analyses

Exploration, EarlyView.
Obesity‐linked hypercoagulation is driven by fibrinogen overproduction in a specific hepatocyte cluster via IL6 signalling. Genetic and mechanistic studies reveal this pathway as a key target for therapies to mitigate clotting risks and associated complications in obese individuals.
Shumin Li, Gengchen Feng, Xin Huang, Xiao Teng, Ziyi Yang, Yue Liu, Yonghui Jiang, Tao Zhu, Teng Liu, Yunfei Xu, Chang Pan, Han Zhao, Shaozhuang Liu, Shigang Zhao, Zi‐Jiang Chen   +14 more
wiley   +1 more source