Results 11 to 20 of about 1,863,899 (386)
Cholesterol oxides inhibit cholesterol esterification by lecithin: cholesterol acyl transferase [PDF]
Brazilian Journal of Pharmaceutical Sciences, 2009 Cholesterol oxides are atherogenic and can affect the activity of diverse important enzymes for the lipidic metabolism. The effect of 7β-hydroxycholesterol, 7-ketocholesterol, 25-hydroxycholesterol, cholestan-3β,5α,6β-triol,5,6β ...
Eder de Carvalho Pincinato +2 more
doaj +4 more sources
Biomedicines, 2022 Residual cardiovascular disease event risk, following statin use and low-density lipoprotein cholesterol (LDL-C) reduction, remains an important and common medical conundrum.
Harold Superko, Brenda Garrett
doaj +1 more source
Cholesterol and Cholesterol Esters in Mycoplasma [PDF]
Journal of General Microbiology, 1965 Free and esterified cholesterol were determined in the lipid extract of nine parasitic and saprophytic Mycoplasma strains. The saprophytic strains were usally free from esterified cholesterol. Esterified cholesterol was found in the parasitic strains at a ratio of 1:8 to 1:3 to free cholesterol; in the growth medium the ratio was about 4:1 [4-14C ...
M. Argaman, Shmuel Razin
openaire +3 more sources
Tracking cell cholesterol with cholesterol oxidase.
Journal of Lipid Research, 1992 Sterols are ubiquitous and essential constituents of all eukaryotic cells, found either esterified and stored in droplet form (l), or unesterified and integrated into bilayers (2) . Sterols not only play a major structural role in membranes, but serve as precursors for steroid hormones and bile acids (3). The distribution of cholesterol within the cell
Y Lange
doaj +4 more sources
Signal Transduction and Targeted Therapy, 2022 Disturbed cholesterol homeostasis plays critical roles in the development of multiple diseases, such as cardiovascular diseases (CVD), neurodegenerative diseases and cancers, particularly the CVD in which the accumulation of lipids (mainly the ...
Yajun Duan +5 more
semanticscholar +1 more source
Journal of Extracellular Vesicles, 2022 Tumour cells are characterized by having lost their differentiation state. They constitutively secrete small extracellular vesicles (sEV) called exosomes when they come from late endosomes.
Michel Record +14 more
doaj +1 more source
Liposomes: Structure, Biomedical Applications, and Stability Parameters With Emphasis on Cholesterol
Frontiers in Bioengineering and Biotechnology, 2021 Liposomes are essentially a subtype of nanoparticles comprising a hydrophobic tail and a hydrophilic head constituting a phospholipid membrane. The spherical or multilayered spherical structures of liposomes are highly rich in lipid contents with ...
Pooria Nakhaei +8 more
semanticscholar +1 more source
Clinical Chemistry, 1972 A method for estimating the cholesterol content of the serum low-density lipoprotein fraction (Sf0-20) is presented. The method involves measurements of fasting plasma total cholesterol, triglyceride, and high-density lipoprotein cholesterol ...
W. T. Friedewald +2 more
semanticscholar +1 more source
Breaking the Cycle, Cholesterol Cycling, and Synapse Damage in Response to Amyloid-ß [PDF]
, 2017 Soluble amyloid-β (Aβ) oligomers, a key driver of pathogenesis in Alzheimer disease, bind to cellular prion proteins (PrPC) expressed on synaptosomes resulting in increased cholesterol concentrations, movement of cytoplasmic phospholipase A2 (cPLA2) to ...
Bate, C
core +2 more sources
Cholesterol Efflux and Reverse Cholesterol Transport [PDF]
, 2014 Both alterations of lipid/lipoprotein metabolism and inflammatory events contribute to the formation of the atherosclerotic plaque, characterized by the accumulation of abnormal amounts of cholesterol and macrophages in the artery wall. Reverse cholesterol transport (RCT) may counteract the pathogenic events leading to the formation and development of ...
FAVARI, Elda +5 more
openaire +5 more sources