Results 11 to 20 of about 1,976,779 (394)

Small Dense LDL: Scientific Background, Clinical Relevance, and Recent Evidence Still a Risk Even with ‘Normal’ LDL-C Levels

open access: yesBiomedicines, 2022
Residual cardiovascular disease event risk, following statin use and low-density lipoprotein cholesterol (LDL-C) reduction, remains an important and common medical conundrum.
Harold Superko, Brenda Garrett
doaj   +1 more source

27-Hydroxylation of oncosterone by CYP27A1 switches its activity from pro-tumor to anti-tumor

open access: yesJournal of Lipid Research, 2023
Oncosterone (6-oxo-cholestane-3β,5α-diol; OCDO) is an oncometabolite and a tumor promoter on estrogen receptor alpha-positive breast cancer (ER(+) BC) and triple-negative breast cancers (TN BC). OCDO is an oxysterol formed in three steps from cholesterol:
Silia Ayadi   +7 more
doaj   +1 more source

Cholesterol and Cholesterol Esters in Mycoplasma [PDF]

open access: yesJournal of General Microbiology, 1965
Free and esterified cholesterol were determined in the lipid extract of nine parasitic and saprophytic Mycoplasma strains. The saprophytic strains were usally free from esterified cholesterol. Esterified cholesterol was found in the parasitic strains at a ratio of 1:8 to 1:3 to free cholesterol; in the growth medium the ratio was about 4:1 [4-14C ...
M, ARGAMAN, S, RAZIN
openaire   +2 more sources

Regulation of cholesterol homeostasis in health and diseases: from mechanisms to targeted therapeutics

open access: yesSignal Transduction and Targeted Therapy, 2022
Disturbed cholesterol homeostasis plays critical roles in the development of multiple diseases, such as cardiovascular diseases (CVD), neurodegenerative diseases and cancers, particularly the CVD in which the accumulation of lipids (mainly the ...
Yajun Duan   +5 more
semanticscholar   +1 more source

Targeting the liver X receptor with dendrogenin A differentiates tumour cells to secrete immunogenic exosome‐enriched vesicles

open access: yesJournal of Extracellular Vesicles, 2022
Tumour cells are characterized by having lost their differentiation state. They constitutively secrete small extracellular vesicles (sEV) called exosomes when they come from late endosomes.
Michel Record   +14 more
doaj   +1 more source

Liposomes: Structure, Biomedical Applications, and Stability Parameters With Emphasis on Cholesterol

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Liposomes are essentially a subtype of nanoparticles comprising a hydrophobic tail and a hydrophilic head constituting a phospholipid membrane. The spherical or multilayered spherical structures of liposomes are highly rich in lipid contents with ...
Pooria Nakhaei   +8 more
semanticscholar   +1 more source

Inhibition of pancreatic cholesterol esterase reduces cholesterol absorption in the hamster [PDF]

open access: yes, 2004
BACKGROUND: Pancreatic cholesterol esterase has three proposed functions in the intestine: 1) to control the bioavailability of cholesterol from dietary cholesterol esters; 2) to contribute to incorporation of cholesterol into mixed micelles; and 3) to ...
Contos, Linda M   +4 more
core   +2 more sources

Association between cholesterol-phospholipid vesicles and cholesterol crystals in human gallbladder bile [PDF]

open access: yes, 1989
Rapid aggregation of cholesterol-phospholipid vesicles in gallbladder bile seems to be the first event in the production of cholesterol crystals, a prerequisite for cholesterol gallstone formation.
Jüngst, Dieter   +1 more
core   +1 more source

A randomized controlled trial to evaluate the effects of high Protein Complete (lActo) VEgetaRian (PACER) diet in non-diabetic obese Asian Indians in North India

open access: yesHeliyon, 2017
In view of the increasing prevalence of obesity in largely vegetarian Asian Indians, it is important to research a high protein, low carbohydrate vegetarian diet.
Swati Bhardwaj   +5 more
doaj   +1 more source

Low-dose ursodeoxycholic acid prolongs cholesterol nucleation time in gallbladder bile of patients with cholesterol gallstones [PDF]

open access: yes, 1989
The high rate of stone recurrence represents a drawback of non-surgical therapy of cholesterol gallstone disease. Although most studies report that long-term bile acid treatment does not have protective effects, preliminary results suggest that low-dose ...
Brenner, Gerhard   +3 more
core   +1 more source

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