Results 11 to 20 of about 1,474,337 (344)

Tracking cell cholesterol with cholesterol oxidase.

open access: yesJournal of Lipid Research, 1992
Sterols are ubiquitous and essential constituents of all eukaryotic cells, found either esterified and stored in droplet form (l), or unesterified and integrated into bilayers (2) . Sterols not only play a major structural role in membranes, but serve as precursors for steroid hormones and bile acids (3). The distribution of cholesterol within the cell
Y Lange
doaj   +4 more sources

Cholesterol oxides inhibit cholesterol esterification by lecithin: cholesterol acyl transferase [PDF]

open access: yesBrazilian Journal of Pharmaceutical Sciences, 2009
Cholesterol oxides are atherogenic and can affect the activity of diverse important enzymes for the lipidic metabolism. The effect of 7β-hydroxycholesterol, 7-ketocholesterol, 25-hydroxycholesterol, cholestan-3β,5α,6β-triol,5,6β ...
Eder de Carvalho Pincinato   +2 more
doaj   +4 more sources

Small Dense LDL: Scientific Background, Clinical Relevance, and Recent Evidence Still a Risk Even with ‘Normal’ LDL-C Levels

open access: yesBiomedicines, 2022
Residual cardiovascular disease event risk, following statin use and low-density lipoprotein cholesterol (LDL-C) reduction, remains an important and common medical conundrum.
Harold Superko, Brenda Garrett
doaj   +1 more source

Cholesterol and Cholesterol Esters in Mycoplasma [PDF]

open access: yesJournal of General Microbiology, 1965
Free and esterified cholesterol were determined in the lipid extract of nine parasitic and saprophytic Mycoplasma strains. The saprophytic strains were usally free from esterified cholesterol. Esterified cholesterol was found in the parasitic strains at a ratio of 1:8 to 1:3 to free cholesterol; in the growth medium the ratio was about 4:1 [4-14C ...
M. Argaman, Shmuel Razin
openaire   +3 more sources

27-Hydroxylation of oncosterone by CYP27A1 switches its activity from pro-tumor to anti-tumor

open access: yesJournal of Lipid Research, 2023
Oncosterone (6-oxo-cholestane-3β,5α-diol; OCDO) is an oncometabolite and a tumor promoter on estrogen receptor alpha-positive breast cancer (ER(+) BC) and triple-negative breast cancers (TN BC). OCDO is an oxysterol formed in three steps from cholesterol:
Silia Ayadi   +7 more
doaj   +1 more source

Targeting the liver X receptor with dendrogenin A differentiates tumour cells to secrete immunogenic exosome‐enriched vesicles

open access: yesJournal of Extracellular Vesicles, 2022
Tumour cells are characterized by having lost their differentiation state. They constitutively secrete small extracellular vesicles (sEV) called exosomes when they come from late endosomes.
Michel Record   +14 more
doaj   +1 more source

Association between cholesterol-phospholipid vesicles and cholesterol crystals in human gallbladder bile [PDF]

open access: yes, 1989
Rapid aggregation of cholesterol-phospholipid vesicles in gallbladder bile seems to be the first event in the production of cholesterol crystals, a prerequisite for cholesterol gallstone formation.
Jüngst, Dieter   +1 more
core   +1 more source

Cholesterol Efflux and Reverse Cholesterol Transport [PDF]

open access: yes, 2014
Both alterations of lipid/lipoprotein metabolism and inflammatory events contribute to the formation of the atherosclerotic plaque, characterized by the accumulation of abnormal amounts of cholesterol and macrophages in the artery wall. Reverse cholesterol transport (RCT) may counteract the pathogenic events leading to the formation and development of ...
FAVARI, Elda   +5 more
openaire   +5 more sources

Inhibition of pancreatic cholesterol esterase reduces cholesterol absorption in the hamster [PDF]

open access: yes, 2004
BACKGROUND: Pancreatic cholesterol esterase has three proposed functions in the intestine: 1) to control the bioavailability of cholesterol from dietary cholesterol esters; 2) to contribute to incorporation of cholesterol into mixed micelles; and 3) to ...
Contos, Linda M   +4 more
core   +2 more sources

A randomized controlled trial to evaluate the effects of high Protein Complete (lActo) VEgetaRian (PACER) diet in non-diabetic obese Asian Indians in North India

open access: yesHeliyon, 2017
In view of the increasing prevalence of obesity in largely vegetarian Asian Indians, it is important to research a high protein, low carbohydrate vegetarian diet.
Swati Bhardwaj   +5 more
doaj   +1 more source

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