Results 61 to 70 of about 1,976,779 (394)

Safety and Efficacy of Bempedoic Acid to Reduce LDL Cholesterol

open access: yesNew England Journal of Medicine, 2019
Background Short‐term studies have shown that bempedoic acid, an inhibitor of ATP citrate lyase, reduces levels of low‐density lipoprotein (LDL) cholesterol.
K. Ray   +7 more
semanticscholar   +1 more source

Measurement of Total Cholesterol, HDL-Cholesterol, and LDL-Cholesterol

open access: yesClinics in Laboratory Medicine, 1989
Plasma concentrations of LDL and HDL are generally measured in terms of their cholesterol content. This requires the separation of the appropriate lipoprotein-containing fractions. The separation and measurement of each fraction are described.
openaire   +2 more sources

Serum cholesterol response to dietary cholesterol [PDF]

open access: yesThe American Journal of Clinical Nutrition, 1984
Serum cholesterol change, delta Chol mg/dl, from change only in dietary cholesterol, mg/1,000 kcal, x, was analyzed with data from 39 controlled experiments on 64 adults with the model delta Chol = b(x2k-x1k). Values of b were found by iteration for exponents k = 0.3 to k = i.0 yielding eight regression equations to check predicted against observed ...
openaire   +3 more sources

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

open access: yesFEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia   +5 more
wiley   +1 more source

Nonpharmacological cholesterol-lowering approach: Managing cholesterol naturally

open access: yesCHRISMED Journal of Health and Research, 2015
Cholesterol is a lipid molecule which is biosynthesized by all animal cells. Also, it is an essential structural component of cell membranes which is normally required for maintaining both fluidity and membrane structural integrity. Dyslipidemia is known
Lubna Mahmood
doaj   +1 more source

Impact of Cholesterol on Voids in Phospholipid Membranes

open access: yes, 2004
Free volume pockets or voids are important to many biological processes in cell membranes. Free volume fluctuations are a prerequisite for diffusion of lipids and other macromolecules in lipid bilayers.
Almeida   +43 more
core   +1 more source

Sprouty2 loss‐induced IL6 drives castration‐resistant prostate cancer through scavenger receptor B1 [PDF]

open access: yes, 2018
Metastatic castration‐resistant prostate cancer (mCRPC) is a lethal form of treatment‐resistant prostate cancer and poses significant therapeutic challenges.
Ahmad, Imran   +16 more
core   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Lipid Intake and Breast Cancer Risk: Is There a Link? A New Focus and Meta-Analysis

open access: yesEuropean Journal of Breast Health, 2022
Objective:To determine if there is an association between total lipid intake, saturated fatty acid (SFA), Poly- and Mono-Unsaturated Fatty Acid (PUFA and MUFA) and cholesterol intake and breast cancer risk.Materials and Methods:We conducted a systematic ...
Massimo Lodi   +5 more
doaj   +1 more source

Effect of vitamin D on proteinuria, lipid status, glicoregulation and C-reactive protein in patients with type-2 diabetes mellitus [PDF]

open access: yesVojnosanitetski Pregled, 2020
Background/Aim. Vitamin D insufficiency/deficiency is often present in patients with type-2 diabetes mellitus (DM) and could present a risk factor for rapid progression of diabetic nephropathy and for higher incidence of cardiovascular events. The aim of
Petrović Marijana   +11 more
doaj   +1 more source

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