Results 211 to 220 of about 1,294,493 (295)

Aza‐Büchner–Curtius–Schlotterbeck Reaction Enables Selective Construction of Quaternary Carbon Centers

open access: yesAngewandte Chemie International Edition, EarlyView.
We introduce the Aza‐Büchner–Curtius–Schlotterbeck (ABCS) reaction: A mild, catalyst‐free method for homologating aryl imines. Diverging from the traditional BCS mechanism, the diazo intermediate undergoes selective C─C insertion to form an all‐carbon quaternary center.
Simon O. Angerer   +6 more
wiley   +1 more source

The tRNA‐Modification Geranyl‐2‐Thiouridine Enables RNA‐Lipid Association

open access: yesAngewandte Chemie International Edition, EarlyView.
We report the preparation of mono‐ to tri‐geranylated RNA and the association of the hydrophobic RNA with membranes for future efficient incorporation of RNA into liposomes. ABSTRACT The packaging of RNA in lipid nanoparticles for protection and delivery was key for the development of mRNA vaccines and therapeutics. Formulation requires the addition of
Johannes Singer   +3 more
wiley   +1 more source

Physicochemical Characterization and Technological‐Functional Properties of Brazil Nut Flour and Protein Concentrate

open access: yesJournal of the American Oil Chemists' Society, EarlyView.
Representation of the graphical abstract of the investigation of physicochemical, functional, and technological properties and amino acid profile of partially defatted flour and protein concentrate from Brazil nuts. ABSTRACT It was investigated the physicochemical, functional and technological properties and amino acid profile of partially defatted ...
Ana Vânia Carvalho   +5 more
wiley   +1 more source

Type 1 diabetes is associated with an increase in cholesterol absorption markers but a decrease in cholesterol synthesis markers in a young adult population. [PDF]

open access: yesJ Clin Lipidol, 2019
Semova I   +15 more
europepmc   +1 more source

Comparative Profiles of Lipophilic Nutrients and In Vitro Antioxidant Activity in Commercial Arabica and Robusta Green Coffee Beans

open access: yesJournal of the American Oil Chemists' Society, EarlyView.
Integrated compositional profiling of ten commercial green coffee lots showed higher mean total phenolic content, DPPH radical‐scavenging activity, β‐carotene, and total phytosterols in Robusta‐labeled lots, whereas Arabica‐labeled lots showed higher mean total tocopherols and total measured fatty acids.
Muyny Chhom   +2 more
wiley   +1 more source

NPC1L1-dependent intestinal cholesterol absorption requires ganglioside GM3 in membrane microdomains. [PDF]

open access: yesJ Lipid Res, 2018
Nihei W   +12 more
europepmc   +1 more source

Influence of Direct Saponification Conditions on Sterol Yield and Composition of the Unsaponifiable Fraction of the Microalga Isochrysis galbana and the Seaweed Ascophyllum nodosum

open access: yesJournal of the American Oil Chemists' Society, EarlyView.
ABSTRACT Saponification is a key step for recovering the unsaponifiable fraction (USF) of lipids, which contains bioactive sterols, tocopherols, and carotenoids. This study optimized direct saponification conditions (50–300 g L−1 KOH; 60°C–100°C) to recover sterol‐rich USFs from the microalga Isochrysis galbana and the brown seaweed Ascophyllum nodosum,
Mina Zareie, Suzanne M. Budge
wiley   +1 more source

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