Results 251 to 260 of about 636,959 (293)
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CHOLESTEROL BIOSYNTHESIS: THE STARVATION BLOCK
Canadian Journal of Biochemistry and Physiology, 1957Partial localization of the metabolic block in cholesterol biosynthesis from acetate by starved rat liver homogenates has been achieved. Experimental evidence indicates that this block is located in the biosynthetic pathway between β-hydroxy-β-methyl glutaric acid and squalene.
J F, SCAIFE, B B, MIGICOVSKY
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Regulation of dolichol and of cholesterol biosynthesis in cholesterol-fed rabbits
Archives of Biochemistry and Biophysics, 1981Abstract The feeding of rabbits with a diet supplemented with 2% cholesterol caused a significant increase in the concentration of serum and hepatic microsomal cholesterol while not affecting serum high-density lipoprotein cholesterol concentration. The concentration of cytochrome b5 was also increased in the cholesterol-fed rabbits but no change in ...
D A, White +6 more
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Studies on biosynthesis of cholesterol. IX. Zymosterol as a precursor of cholesterol
Archives of Biochemistry and Biophysics, 1957Summary Zymosterol-C 14 obtained from the incubation of yeast with carboxyllabeled sodium acetate was given to rats by stomach tube and injected intravenously. In the feeding experiments it was converted to cholesterol-C 14 in good yields; the yields were somewhat smaller in an injection experiment.
G J, ALEXANDER, E, SCHWENK
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Oxylanosterols as modifiers of cholesterol biosynthesis
Progress in Lipid Research, 1995In this review, the thinking and strategy that lead to the design of mechanism-based inhibitors of cholesterol biosynthesis have been recounted. This work began with a purely biochemical perspective on the mechanism of lanosterol demethylation. The final efforts focused on pharmacology and drug design thus bringing the basic science effort to a ...
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Cholesterol Biosynthesis in Hepatocytes
Biochemical Society Transactions, 1978G F, Gibbons, C R, Pullinger
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Biosynthesis of cholesterol in the baboon
Biochimica et Biophysica Acta, 1962D, KRITCHEVSKY +2 more
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The biosynthesis of cholesterol
Ergebnisse der Physiologie Biologischen Chemie und Experimentellen Pharmakologie, 1965openaire +2 more sources