Results 241 to 250 of about 1,222,670 (353)

Kinetically Controlled Self‐Assembly of a Lipophilic Fluorophore with Phenylalanine‐Based Diamides in Artificial Lipid Droplets

Small, EarlyView.
Fibrous aggregates in triolein are constructed from a lipophilic donor–acceptor fluorophore bearing two phenylalanine‐based diamide units. Spectroscopic analyses and fluorescence imaging revealed a kinetically trapped state persisting for hours, enabling seeded modulation of aggregate size in artificial lipid droplets encapsulating triolein within a ...
Miku Naruse, Soichiro Ogi, Keiji Kajiwara, Natsumi Fukaya, Yoshikatsu Sato, Masayasu Taki, Shigehiro Yamaguchi   +6 more
wiley   +1 more source

Mechanism elucidation of cell‐selective fluorescent probes

Smart Molecules, EarlyView.
This perspective outlines five mechanistic strategies—Protein‐oriented, carbohydrate‐oriented, lipid‐oriented, gating‐oriented, and metabolism‐oriented live‐cell distinctions—for achieving cell‐selective fluorescence in live‐cell imaging. By classifying probes based on their interactions with proteins, carbohydrates, lipids, transporters, or metabolic ...
Sourav Sarkar, Young‐Tae Chang
wiley   +1 more source

Lipidomics-Based Analysis of the Regulatory Effects of Phytosterol Esters on Lactation Performance and Lipid Metabolism in Tarim <i>Bactrian camels</i>. [PDF]

Animals (Basel)
Dou P, Shen Y, Zheng W, Zhu L, Chen Y, Li F.   +5 more
europepmc   +1 more source

Single‐Particle Characterization Reveals Heterogeneous Extracellular Vesicle Fusion with Liposomes

Small Methods, EarlyView.
This study used five orthogonal single‐particle techniques to compare how common mechanical methods fuse extracellular vesicles with liposomes. By quantifying fused‐particle yield, purity, and vesicle integrity, we found that freeze‐thaw and sonication generated the highest fusion but that all methods introduced membrane perturbation or damage.
Rachel R. Mizenko, Vishalakshi Arun, David Meshkanian, Neona M. Lowe, Henna Mohabbat, Aijun Wang, Randy P. Carney   +6 more
wiley   +1 more source

Cholesterol Ester Storage Disease in Two Field Spaniels With Lysosomal Acid Lipase Deficiency. [PDF]

J Vet Intern Med
Syrjä P, Ylenius MMH, Kråkström M, Dickens AM, Rautala E, Huupponen A, Eriksson A, Viitanen SJ.   +7 more
europepmc   +1 more source

Cardenolide‐Engineered Extracellular Vesicles Augment Drug Uptake and Cytotoxicity in Non‐small Cell Lung Cancer Cells

Small Methods, EarlyView.
Cardenolide‐functionalized extracellular vesicles enable targeted delivery of the chemotherapeutic doxorubicin to A549 lung cancer cells by binding Na+/K+‐ATPase, which is overexpressed in these cells. Surface‐modified, drug‐loaded EVs exhibit enhanced cytotoxicity compared to unmodified EVs and free drug, suggesting this system may lower the effective
Maja Dorfner, Anika Mifka, Rodrigo Maia de Pádua, Izabella Thaís da Silva, Iara Zanella Guterres, Lorenzo Sana, Gregor Fuhrmann, Jennifer Munkert   +7 more
wiley   +1 more source

Mendelian randomization analysis of lipidomic profiles and thyroid cancer risk in European populations. [PDF]

Discov Oncol
Li S, Yu H, Zhang D, Li Y.
europepmc   +1 more source

Unilateral mastication‐induced memory deficits linked to disrupted hippocampal cholesterol metabolism in rats

VIEW, EarlyView.
Unilateral mastication, a common oral habit, induces cognitive decline in rats by disrupting hippocampal cholesterol metabolism. It triggers astrocyte hyperplasia, enhances cholesterol synthesis, impairs transport/degradation, and reduces 24‐hydroxycholesterol (24‐OHC), ultimately damaging synaptic function.
Xiaoting Zhai, Yifan Hu, Rongchen Xu, Xinyu Xu, Bowen Ma, Dongzong Huang, Hongchen Liu, Hongbo Li, Yuan Hu, Hua Jiang   +9 more
wiley   +1 more source

Lipid Composition and Thermotropic Properties of Meibum of Animal Models and Humans with Meibomian Gland Dysfunction. [PDF]

Int J Mol Sci
Butovich IA, Wojtowicz JC, Wilkerson A, Yuksel S.   +3 more
europepmc   +1 more source

Advances in cholesterol and lipoproteins detection for healthcare: A review

VIEW, EarlyView.
Cholesterol is one of the main biomarkers related to the development of cardiovascular diseases. Its detection still relies on traditional methods of analysis, such as gas and liquid chromatographies. Detection of free cholesterol in saliva with redox or enzymatic sensors or detection of lipoproteins in blood with aptamer sensors are currently the most
Jacopo Giaretta, Somayeh Fardindoost, Azadeh Abdi, Kaveh Yazdani, Longfei Yin, Syamak Farajikhah, Mina Hoorfar, Fariba Dehghani   +7 more
wiley   +1 more source