Results 241 to 250 of about 586,832 (295)

Dysregulated Cholesterol Metabolism and Its Impact on the Tumour Immune Response in Colorectal Cancer. [PDF]

J Cell Mol Med
Zhang C, Miao Z, Xu Y, Zhu X, Shi T.
europepmc   +1 more source

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

Advanced NanoBiomed Research, EarlyView.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

Cholesterol Metabolism Regulated Nanoliposome Ameliorates Chemo/Photothermal Therapy Reversing CD8⁺ T Cell Exhaustion. [PDF]

Exploration (Beijing)
Xue P, Bai T, Zhuang H, All AH, Yan S, Zeng X.   +5 more
europepmc   +1 more source

Liposomal Delivery of L‐2‐Hydroxyglutarate for Targeting Epigenetic Dysregulation in Osteoarthritis

Advanced NanoBiomed Research, EarlyView.
Osteoarthritis involves cartilage degeneration, inflammation, and epigenetic dysregulation. A liposomal formulation of the TET1 inhibitor L‐2‐hydroxyglutarate to overcome rapid joint clearance was developed. The formulation showed good physicochemical properties, reduced inflammatory and catabolic gene expression in chondrocytes, and alleviated ...
Denise Murgia, Akshay Pandey, Raffaele Spanò, Bianca Martins Estevão, Roberto Palomba, Greta Avancini, Tamaghna Gupta, Ana Maria Lopez Estevez, Stuart B. Goodman, Nidhi Bhutani, Paolo Decuzzi   +10 more
wiley   +1 more source

Effects of Cholesterol Metabolism on Corneal Endothelial Dysfunction in Patients With Type 1 Diabetes. [PDF]

Invest Ophthalmol Vis Sci
Ren Z, Li Z, Dou S, Zhao H, Xie L.
europepmc   +1 more source

Establishing an atherosclerosis diagnostic model based on WGCNA and machine learning algorithms with key genes in cholesterol metabolism and ferroptosis, and revealing the regulatory role of HMOX1 in cellular ferroptosis. [PDF]

Front Cardiovasc Med
Fan Z, Liu C, Liu Y, Hong Z, Zhong J, Yang B, Yuan Y.   +6 more
europepmc   +1 more source

Ferulic Acid Attenuates Heat Stress-Induced Hepatic and Intestinal Oxidative Stress and Cholesterol Metabolism Dysregulation in Juvenile Blunt Snout Bream (Megalobrama amblycephala). [PDF]

Int J Mol Sci
Lin Y, Leng X, Qian L, Miao L, Li X, Jiang W, Lu S, Gu Z.   +7 more
europepmc   +1 more source

IGF2BP1-mediated methylation of ABCA1 facilitates tumor progression by affecting cholesterol metabolism in lung adenocarcinoma. [PDF]

Amino Acids
Xu S, Liu K, Chen Z, Tang W, Chen Z.
europepmc   +1 more source

Single-cell profiling deciphering cholesterol metabolism dysregulation in metastatic uveal melanoma and implicating SLC45A2 in its prognosis. [PDF]

Front Immunol
Zhou Y, Cao Y, Li Z, Lei X, Gao Q, Yao W, Guan J, Lu G, Deng H, Zhang L, Deng X, Chen Z, Xing Y.   +12 more
europepmc   +1 more source