Results 91 to 100 of about 1,698,727 (261)

Changes to cholesterol trafficking in macrophages by Leishmania parasites infection [PDF]

, 2017
Leishmania spp. are protozoan parasites that are transmitted by sandfly vectors during blood sucking to vertebrate hosts and cause a spectrum of diseases called leishmaniases.
Anderson, Andrade-Neto, Antoine, Bansal, Berman, Blanchette-Mackie, Burack, Carstea, Carvalho, Chakraborty, Chattopadhyay, Collins, Coombs, Coppens, De Cicco, Desvergne, Duclos, Edwards, Ehrenman, Fernandes, Ghosh, Ghosh, Ghosh, Ginger, Ginger, Goldstein, Groener, Hamid, Hart, Ikonen, Infante, Johndrow, Kima, Kima, Kok, Kwon, Lal, Lecoeur, Lippuner, Livak, Majumder, Maxfield, McIntosh, Misslitz, Naureckiene, Neufeld, Osorio y Fortea, Ovalle-Bracho, Paape, Paape, Pereira, Portugal, Pucadyil, Rabhi, Redgrave, Roberts, Rosenzweig, Rub, Russell, Saunders, Sen, Shamshiev, Soares, Sorensen, Tetley, Tewary, Tontonoz, Weinheber   +67 more
core   +2 more sources

Lysosomal Acid Lipase Deficiency Impairs Regulation of ABCA1 Gene and Formation of High Density Lipoproteins in Cholesteryl Ester Storage Disease*

Journal of Biological Chemistry, 2011
ATP-binding cassette transporter A1 (ABCA1) mediates the rate-limiting step in high density lipoprotein (HDL) particle formation, and its expression is regulated primarily by oxysterol-dependent activation of liver X receptors.
K. Bowden, Nicolas J Bilbey, Leanne M. Bilawchuk, E. Boadu, Rohini Sidhu, D. Ory, H. Du, Teddy Chan, G. Francis   +8 more
semanticscholar   +1 more source

Socioeconomic Status Modifies the Risk of Gastric Cancer Through Metabolomic Signature: Evidence From a Prospective Cohort Study

iNew Medicine, EarlyView.
ABSTRACT The role of metabolites in the association between socioeconomic status (SES) and gastric cancer remains unclear. This study seeks to elucidate the role of metabolomics in the association between SES and gastric cancer, as well as to explore potential interactions between metabolic signatures and polygenic risk score (PRS) in the context of ...
Shiyin Meng, Shangxin Zhang, Jing Wang, Zhuoyi Wu, Wenjie Xuan, Jiawei Zhang, Qihong Zhao, Anla Hu, Jing Ni   +8 more
wiley   +1 more source

Investigation of flow uniformity and pressure recovery in a turning diffuser by means of baffles [PDF]

, 2013
Turning diffuser is an engineering device that is widely used in the industry to reduce the flow velocity as well as change the direction of the flow. Having a curvature shape causes its performance to decrease in terms of pressure recovery (Cp) and flow
Asher, Brake, Burridge, Chin Fhong Soon, DeHart, Engelman, Feingold, Frank, Guille, Hatijah Basri, Hwang, Hyde, Kainulainen, Kian Sek Tee, Kirfel, Kravchenko, Larjava, Li, Lockwood, Mansour Youseffi, Morgan Clive Thomas Denyer, Munoz, Nafarizal Nayan, Nguyen, Nick Blagden, Norlen, O’Toole, Rebecca F. Berends, Small, Soon, Soon, Soon, Soon, Stanley, Stanley, Unna, Wan Ibtisam Wan Omar, Woolverton, Ziboh   +38 more
core   +1 more source

Impact of CYP2C19 Genotype Variants on PCSK9 Inhibitor Efficacy in Lipid‐Lowering Among Patients With Symptomatic Intracranial Atherosclerotic Stenosis

Lipids, EarlyView.
ABSTRACT Ischemic stroke is frequently associated with symptomatic intracranial atherosclerotic stenosis (sICAS), is a leading cause of global disability and mortality. Current guidelines recommend dual antiplatelet and intensive statin therapies. Proprotein convertase subtilisin 9/kexin type 9 (PCSK9) inhibitors have emerged as a potent lipid‐lowering
Chao Zhao, Nuan Wang, Di Shi, Hao Zhou, Dan Chen, Guofang Chen   +5 more
wiley   +1 more source

Cold EI—The Way to Improve GC‐MS and Increase Its Range of Applications

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Gas chromatography‐mass spectrometry (GC‐MS) with Cold electron ionization (EI) is based on interfacing the GC and MS with a supersonic molecular beam (SMB) along with electron ionization of vibrationally cold sample compounds in the SMB in a contact‐free fly‐through ion source (hence the name Cold EI).
Aviv Amirav, Benny Neumark, Oneg Elkabets, Alex Yakovchuk   +3 more
wiley   +1 more source

Cholesteryl ester turnover in human plasma lipoproteins during cholestyramine and clofibrate therapy

Journal of Lipid Research, 1970
The effects of cholestyramine and of clofibrate on the turnover rates of individual cholesteryl esters in whole human plasma and in each of the three classes of plasma lipoproteins have been studied. Four hyperlipidemic patients (two under treatment with
Dewitt S. Goodman, Robert P. Noble
doaj   +1 more source

Evacetrapib is a novel, potent, and selective inhibitor of cholesteryl ester transfer protein that elevates HDL cholesterol without inducing aldosterone or increasing blood pressure

Journal of Lipid Research, 2011
Cholesteryl ester transfer protein (CETP) catalyses the exchange of cholesteryl ester and triglyceride between HDL and apoB containing lipoprotein particles.
Guoqing Cao, Thomas P. Beyer, Youyan Zhang, R. Schmidt, Yan Q. Chen, S. L. Cockerham, K. Zimmerman, S. Karathanasis, E. Cannady, T. Fields, N. Mantlo   +10 more
semanticscholar   +1 more source

Associations of Vestibular Disorders With Risk of All‐Cause and Cause‐Specific Dementia: A Longitudinal Cohort Study in UK Biobank

Sensory Neuroscience, EarlyView.
ABSTRACT To explore associations of vestibular disorders with all‐cause and cause‐specific dementia and underlying biological mechanisms/neuroimaging changes. A population‐based cohort study of 406,348 UK Biobank participants was conducted. Inverse probability of treatment weighting (IPTW) balanced baseline covariates, and Cox proportional hazards ...
Xiaofei Li, Fan Jiang, Qiuyue Dong, Hao Chen, Hanbing Ji, Alimu Dayimu, Yifan Yu, Guorong Li, Na Li, Peipei Fu, Qi Jing, Maoli Duan, Hongkai Li, Shanquan Chen, Daogong Zhang, Haibo Wang   +15 more
wiley   +1 more source

Effect of fish oil versus lard diets on the chemical and physical properties of low density lipoproteins of nonhuman primates.

Journal of Lipid Research, 1987
Twenty-four adult male African green grivet monkeys were fed diets containing 42% of calories as lard or menhaden oil and 0.76 mg of cholesterol/kcal for a period of 8 months.
J S Parks, B C Bullock
doaj   +1 more source