Results 131 to 140 of about 1,698,727 (261)

Digital Biomarkers for Precision Early Detection of Lung Cancer: Integrating AI‐Driven Multi‐Omics Into Clinical Pathways

open access: yesCancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Background Lung cancer remains the leading cause of cancer‐related mortality worldwide, highlighting the urgent need for earlier detection within real‐world screening and patient management pathways. Recent advances in multi‐omics technologies have created new opportunities for identifying biomarkers associated with early‐stage lung cancer ...
Fan Bu, Zhi‐Qiang Ling
wiley   +1 more source

Formation of cholesterol monohydrate crystals in macrophage-derived foam cells.

open access: yesJournal of Lipid Research, 1994
In a previous study using the J774 macrophage foam cells, we quantitated the accumulation of unesterified (free) cholesterol derived from cholesteryl ester hydrolysis in lysosomes, after phagocytic uptake of cholesteryl ester droplets.
R.K. Tangirala   +7 more
doaj   +1 more source

I405V and -629C/A polymorphisms of the cholesteryl ester transfer protein gene in patients with coronary artery disease [PDF]

open access: yes, 2009
Background: Cholesteryl ester transfer protein (CETP) plays a main role in high-density lipoprotein metabolism. CETP gene possesses several single nucleotide polymorphisms which have been associated with plasma high-density lipoprotein cholesterol (HDL-C)
Darabi Amin, Masoud.   +5 more
core   +1 more source

Lipidomic Analysis of Plasma Extracellular Vesicles from Adiponectin Deficient Mice or Metabolic Syndrome Patients Reveals Pro‐Oxidative and Pro‐Inflammatory Lipid Signatures Correlating with Metabolic Dysfunction

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 2, February 2026.
Adiponectin deficiency remodels the lipid composition of plasma extracellular vesicles (EV), enriching polyunsaturated phospholipids and reducing lysophospholipids. These remodelled EV impact oxidative, inflammatory and metabolic function in recipient cells.
Sungji Cho   +13 more
wiley   +1 more source

Rethinking Statin Dosage in Coronary Disease

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 1, February 2026.
It is widely acknowledged that a sufficient statin dose is important in the management of symptomatic coronary disease, along with weight reduction and appropriate antithrombotic, blood pressure, and diabetes pharmacotherapy. Mid‐range statin doses have been shown to achieve the maximum improvements in total mortality and have the advantage of greater ...
Simon B. Dimmitt   +3 more
wiley   +1 more source

Skin Lipid–Microbe Interplay Links Staphylococcus hominis to Barrier Control in Adult Atopic Dermatitis

open access: yesAllergy, Volume 81, Issue 2, Page 454-467, February 2026.
This study investigates mutual interaction of skin microbes and surface lipids in AD using the advanced method of shotgun lipidomics with ultra‐broad coverage of lipids and 16S amplicon sequencing of tape strips taken from lesional and non‐lesional AD and healthy controls.
Madhumita Bhattacharyya   +14 more
wiley   +1 more source

Mechanisms for the effect of electric and magnetic fields on biological systems Semiannual status report, Jun. - Dec. 1969 [PDF]

open access: yes
Electric and magnetic field effects on structure and properties of cholesteric liquid ...
Baessler, H.   +3 more
core   +1 more source

Portacaval shunt for glycogen storage disease and hyperlipidaemia. [PDF]

open access: yes, 1977
Complete portacaval shunt was used to treat 10 patients with glycogen storage disease. A favourable effect was noted on body growth and a number of metabolic abnormalities.
Benichou, J   +3 more
core  

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