Results 101 to 110 of about 32,808 (269)
Diabetes, Obesity and Metabolism, EarlyView.Abstract Aims Mortality of patients with type 2 diabetes (T2D) after acute myocardial infarction (AMI) is tremendous and massively increased compared to non‐T2D individuals. The reasons are unclear. High‐density lipoprotein (HDL) conducts lipoprotection during AMI, leading to improved outcomes.
Jens Vogt +12 more
wiley +1 more source
Apolipoprotein composition of HDL in cholesteryl ester transfer protein deficiency
Journal of Lipid Research, 2004 Our purpose was to compare HDL subpopulations, as determined by nondenaturing two-dimensional gel electrophoresis followed by immunoblotting for apolipoprotein A-I (apoA-I), apoA-II, apoA-IV, apoCs, and apoE in heterozygous, compound heterozygous, and ...
Bela F. Asztalos +8 more
doaj +1 more source
Molecular Microbiology, EarlyView.Human macrophage transcriptomic responses to Mycobacterium avium (Mav), a major cause of nontuberculous lung disease, were compared to Mycobacterium tuberculosis (Mtb). Both infections activated overlapping immune pathways, including cytokine signaling and GPCRs involved in lipid metabolism, while phospholipases were more strongly regulated by Mav and ...
Gül Kilinç +4 more
wiley +1 more source
Rapid purification of human plasma lipid transfer proteins.
Journal of Lipid Research, 1990 Lipid transfer protein (LTP) was isolated from human plasma after lipoproteins were removed by precipitation with dextran sulfate. Three sequential chromatogrpahic procedures were used: butyl-Toyopearl 650, CM-Toyopearl 650, and Toyopearl HW-55.
T Ohnishi, S Yokoyama, A Yamamoto
doaj +1 more source
A Systematic Approach to Identifying Protein-Ligand Binding Profiles on a Proteome Scale [PDF]
, 2008 Identification of protein-ligand interaction networks on a proteome scale is crucial to address a wide range of biological problems such as correlating molecular functions to physiological processes and designing safe and efficient therapeutics.
Lei Xie +3 more
core +2 more sources
The Evolving Role of Cholesteryl Ester Transfer Protein Inhibition Beyond Cardiovascular Disease.
Pharmacological Research, 2023 Nehal N Mehta +5 more
semanticscholar +1 more source
Plant Biotechnology Journal, EarlyView.ABSTRACT Lipid droplets (LDs) serve as the primary storage site for neutral lipids in plant cells, with growing evidence supporting many additional biological roles, such as in lipid homeostasis, signalling, trafficking, inflammatory responses and inter‐organelle communication.
Abdulsamie Hanano +2 more
wiley +1 more source
Cholesteryl ester transfer protein inhibitors for dyslipidemia: focus on dalcetrapib
Drug Design, Development and Therapy, 2012 Alyse S Goldberg, Robert A HegeleDepartment of Medicine, Schulich School of Medicine and Dentistry, Western University, London, Ontario, CanadaAbstract: Among the noteworthy recent stories in the management and prevention of atherosclerotic ...
Goldberg AS, Hegele RA
doaj
A novel explanation for the reduced LDL cholesterol in severe hypertriglyceridemia.
Journal of Lipid Research, 1989 When [3H]cholesteryl ester-labeled low density (LDL) and intermediate density lipoproteins (IDL) from a normotriglyceridemic, hypercholesterolemic rabbit were injected into severely hypertriglyceridemic, hypercholesterolemic rabbits, 60% of the label ...
A Minnich +2 more
doaj +1 more source
HDL: A molecular view of the "classic" antiatherogenic lipoprotein [PDF]
, 2002 L'estudi del metabolisme de les HDL (lipoproteïnes de densitat alta) i la seva relació amb l'arteriosclerosi és un tema complex, en el qual, recentment, s'han fet avenços importants.
Blanco-Vaca, Francisco +2 more
core