Results 201 to 210 of about 5,014,718 (261)

Long-Term Cholic Acid Therapy in Zellweger Spectrum Disorders. [PDF]

open access: yesCase Rep Gastroenterol, 2018
Heubi JE, Setchell KDR, Bove KE.
europepmc   +1 more source

Cholic acid as a treatment for cerebrotendinous xanthomatosis in adults [PDF]

open access: possibleJournal of Neurology, 2019
Cerebrotendineous xanthomatosis (CTX) is an autosomal recessive disorder of bile acids synthesis. Patients may present with a variety of clinical manifestations: bilateral cataract and chronic diarrhea during childhood, then occurrence of neurological debilitating symptoms in adulthood (cognitive decline, motor disorders). Plasma cholestanol is used as
Jonathan Curot   +13 more
openaire   +4 more sources

Conversion of chenodeoxycholic acid to cholic acid by human CYP8B1

Biological Chemistry, 2018
Abstract The human cytochrome P450 enzyme CYP8B1 is a crucial regulator of the balance of cholic acid (CA) and chenodeoxycholic acid (CDCA) in the liver. It was previously shown to catalyze the conversion of 7α-hydroxycholest-4-en-3-one, a CDCA precursor, to 7α,12α-dihydroxycholest-4-en-3-one, which is an intermediate of CA biosynthesis.
Linbing Fan   +4 more
openaire   +4 more sources

Cholic acid

Trends in Endocrinology & Metabolism
Xi, Luo, Kai, Wang, Changtao, Jiang
openaire   +3 more sources

Catanionic Gels Based on Cholic Acid Derivatives

Langmuir, 2013
In this paper, the preparation and characterization of an anionic and a cationic surfactant obtained by chemical modifications of a natural bile acid (cholic acid) are reported. The bile acid was modified by introducing a diamine or a dicarboxylic aromatic residue on the lateral chain.
DI GREGORIO, MARIA CHIARA   +7 more
openaire   +5 more sources

Insulin- and cholic acid-loaded zein/casein-dextran nanoparticles enhance the oral absorption and hypoglycemic effect of insulin.

Journal of materials chemistry. B, 2021
Diabetes mellitus is the most common metabolic disease in the world. Herein, insulin- and cholic acid-loaded zein nanoparticles with dextran surfaces were fabricated to enhance the oral absorptions of insulin in the intestine and in the liver which is ...
Xiaoyan Bao, K. Qian, Ping Yao
semanticscholar   +1 more source

Microbiological Degradation of Cholic Acid [PDF]

open access: possibleNature, 1957
FOR the microbiological oxidation of cholic acid, two possible pathways different from that found in A. faecalis1 or E. coli2 can be suggested.
Takao Fujii   +3 more
openaire   +2 more sources

Cholic acid and deoxycholic acid induce skeletal muscle atrophy through a mechanism dependent on TGR5 receptor

Journal of Cellular Physiology, 2020
Skeletal muscle atrophy is characterized by the degradation of myofibrillar proteins, such as myosin heavy chain or troponin. An increase in the expression of two muscle‐specific E3 ligases, atrogin‐1 and MuRF‐1, and oxidative stress are involved in ...
J. Ábrigo   +10 more
semanticscholar   +1 more source

Bacterial oxidation of cholic acid

Archives of Biochemistry and Biophysics, 1954
Abstract 1. 1. Ammonium cholate (0.1%) on perfusion through soil yields a substance in the soil perfusate with λ max at 246 mμ in water. This substance is referred to as X246. 2. 2. The organisms responsible for the conversion of cholic acid to X246 have been isolated and are provisionally identified as Nocardia . 3. 3.
P. G. Scholefield   +2 more
openaire   +3 more sources

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