Results 91 to 100 of about 263,913 (277)

Auditory Hair Cell Mechanotransduction Channels Dynamically Shape the Mechanical Properties of Their Membrane Environment

open access: yesAdvanced Science, EarlyView.
This work shows, for the first time, that the stereocilia membrane in cochlear hair cells is dynamically regulated by the mechanotransduction channel to impact the membrane mechanical properties. This work provides direct evidence that the opening and closing associated with the MET channel is regulating the membrane viscosity suggesting that the MET ...
Shefin S. George, Anthony J. Ricci
wiley   +1 more source

Chronic neuropathic pain components in whiplash-associated disorders correlate with metabolite concentrations in the anterior cingulate and dorsolateral prefrontal cortex: a consensus-driven MRS re-examination

open access: yesFrontiers in Medicine
IntroductionWhiplash injury (WHI) is characterised by a forced neck flexion/extension, which frequently occurs after motor vehicle collisions. Previous studies characterising differences in brain metabolite concentrations and correlations with ...
Irene Pinilla-Fernández   +19 more
doaj   +1 more source

One-Carbon Metabolism Nutrients, Genetic Variation, and Diabetes Mellitus [PDF]

open access: yesDiabetes & Metabolism Journal
Diabetes mellitus (DM) affects about 9.3% of the population globally. Hyperhomocysteinemia (HHcy) has been implicated in the pathogenesis of DM, owing to its promotion of oxidative stress, β-cell dysfunction, and insulin resistance.
Jie Zhu   +4 more
doaj   +1 more source

Detection of Metabolites by Proton Ex Vivo NMR, in Vivo MR Spectroscopy Peaks and Tissue Content Analysis: Biochemical-Magnetic Resonance Correlation: Preliminary Results [PDF]

open access: yes, 2009
*Aim*: Metabolite concentrations by in vivo magnetic resonance spectroscopy and ex vivo NMR spectroscopy were compared with excised normal human tissue relaxation times and tissue homogenate contents. *Hypothesis*: Biochemical analysis
Arun Agrawala   +2 more
core   +1 more source

Animal models of NASH: getting both pathology and metabolic context right [PDF]

open access: yes, 2015
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of referral to liver clinics, and its progressive form, non-alcoholic steatohepatitis (NASH), can lead to cirrhosis and end-stage liver disease.
Larter, Claire Z., Yeh, Matthew M.
core   +1 more source

Edible Pneumatic Battery for Sustained and Repeated Robot Actuation

open access: yesAdvanced Science, EarlyView.
This work presents an edible energy source and valve system to power soft, pneumatically driven edible robots. A chemical reaction between sodium bicarbonate and citric acid generates carbon dioxide gas, and a pressure‐triggered edible valve enables self‐repetitive motion of the edible actuator.
Bokeon Kwak   +5 more
wiley   +1 more source

Eggs – a scoping review for Nordic Nutrition Recommendations 2023

open access: yesFood & Nutrition Research
Cardiovascular diseases (CVD), type 2 diabetes (T2D), and cancer are a significant public health burden in the Nordic and Baltic countries. High intake of eggs, mainly due to its high cholesterol content, has been suggested to have adverse health effects.
Jyrki K. Virtanen, Susanna C. Larsson
doaj   +1 more source

Magnetic Resonance Spectroscopy in Diagnosing Brain Tumours? Is it Worth Doing [PDF]

open access: yesInternational Journal of Anatomy Radiology and Surgery, 2019
Introduction: Magnetic Resonance Spectroscopy (MRS) is a non-invasive diagnostic method useful in providing information about specific metabolites in brain tissue that can indicate the presence of tumour, necrotic tissue and other pathologic entities.
Sunita Dashottar   +1 more
doaj   +1 more source

Methionine formation by transmethylation in vitro [PDF]

open access: yes, 1947
We reported in a previous communication (1) that guanidoacetic acid is methylated to creatine by rat liver slices in the presence of choline and either homocysteine or homocystine.
Borsook, Henry, Dubnoff, Jacob W.
core  

Gut Microbial Metabolism and Nonalcoholic Fatty Liver Disease. [PDF]

open access: yes, 2019
The gut microbiome, the multispecies community of microbes that exists in the gastrointestinal tract, encodes several orders of magnitude more functional genes than the human genome. It also plays a pivotal role in human health, in part due to metabolism
Lynch, Susan V   +3 more
core   +1 more source

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