Results 161 to 170 of about 139,290 (260)

Maternal Methyl-Group Donor Intake and Neonatal Birth Size in Singleton IVF Pregnancies. [PDF]

open access: yesNutrients
Bokor S   +10 more
europepmc   +1 more source

Microbiome—pancreatic cancer crosstalk: From tumor biology to therapeutic intervention

open access: yesiMetaOmics, EarlyView.
The intratumoral microbiome acts as a critical regulator in pancreatic cancer progression and therapeutic resistance. This comprehensive review delineates the origins of pancreatic microbes, elucidates their multifaceted mechanisms in driving immune suppression, metabolic reprogramming, and stromal desmoplasia, and highlights the clinical potential of ...
Yuqin Xie   +12 more
wiley   +1 more source

Variability and Magnitude of Choline Levels Across the Psychosis Spectrum: A Meta-analysis. [PDF]

open access: yesSchizophr Bull
Fanshawe JB   +15 more
europepmc   +1 more source

Microbiome and aging: Trajectories of microbiome age across human ecosystems and their systemic effects

open access: yesiMeta, EarlyView.
Microbiome age (MA) has emerged as an innovative biomarker of biological aging, reflecting host aging trajectories through dynamic alterations in microbial composition, function, and host–microbe interactions across multiple body ecosystems. Diverse computational strategies—including traditional machine learning, deep learning, and multi‐omics ...
Zhexin Ni   +26 more
wiley   +1 more source

Maternal and infant gut microbiome

open access: yesiMeta, EarlyView.
The maternal–infant continuum involves critical windows of host–microbiota co‐adaptation. Preconception, maternal and paternal microbiomes modulate immunity and reproduction. During pregnancy, a gut–placenta axis emerges, where microbial metabolites influence fetal growth or contribute to complications like gestational diabetes mellitus (GDM ...
Huidi Wang   +25 more
wiley   +1 more source

Depletion of NAT10 in T cells attenuates metabolic dysfunction-associated steatohepatitis in mice. [PDF]

open access: yesHepatol Commun
Yang Y   +8 more
europepmc   +1 more source

Western Diet Combined With Chemical Induction: A Strategy for Rapid Development of MASLD Pathology in Mice

open access: yesiNew Medicine, EarlyView.
ABSTRACT Objective The molecular mechanisms underlying the development of metabolic‐dysfunction‐associated steatotic liver disease (MASLD) are essential for developing appropriate treatments. The purpose of this study was to establish an MASLD model in mice with rapid and consistent progression.
Ting‐Ting Chen   +10 more
wiley   +1 more source

Analysis of ligand recognition by choline O-acetyltransferase reveals thiol-reactive assay interference and weak ligand affinity in solution. [PDF]

open access: yesJ Biol Chem
Forsgren N   +9 more
europepmc   +1 more source

A Comprehensive Study of Bidirectional Interactions Between the Human Microbiome and Blood Malignancies and Hematologic Conditions: Focus on Novel Therapeutic Strategies

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Microbiota‐targeted therapeutic strategies in hematological disorders. aHSCT: Transplanted immune cells from the donor may attack the recipient's tissues, especially when damage to the intestinal epithelium disrupts the gut microbiota, contributing to GVHD. Maintaining a balanced gut microbiota that supports immune regulation helps reduce GVHD risk and
Alireza Molajafari   +3 more
wiley   +1 more source

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