Results 181 to 190 of about 343,812 (340)

Promotion of 5‐hydroxymethylfurfural synthesis from glucose over AlCl3 catalyst with choline chloride

open access: yesAIChE Journal, EarlyView.
Abstract Efficient production of 5‐hydroxymethylfurfural (HMF) from glucose was achieved in a water‐methyl isobutyl ketone biphasic solvent system over AlCl3 catalyst, using a green and cheap choline chloride (ChCl) salt as a promoter. An optimized HMF yield of 67% was obtained from 0.6 M glucose over 0.06 M AlCl3 with 3.8 M ChCl addition at 140°C ...
Chencong Ruan, Hero Jan Heeres, Jun Yue
wiley   +1 more source

Speech and Language Disorders Associated With 7q31 Deletions Implicating FOXP2

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Some 7q31 deletions encompass FOXP2, a gene long associated with speech and language disorders. Intragenic pathogenic FOXP2 variants cause FOXP2‐related speech and language disorder, which has been well characterized in the literature. Conversely, the phenotype associated with 7q31 deletions is neglected.
Lottie D. Morison   +3 more
wiley   +1 more source

Glycolic Acid‐Based Natural Deep Eutectic Solvents (NADESs) as Catalytic Reaction Media for the Synthesis of β‐Nitro Ketones

open access: yesAsian Journal of Organic Chemistry, EarlyView.
β‐nitro ketones were synthesised via nitration of enones in glycolic acid‐based natural deep eutectic solvents (NADESs), taking advantage of both their green properties as well as their weakly acidic catalytic behavior. The reaction proceeded with stochiometric amounts of nitration agents with both aromatic and aliphatic reactants.
Dario Gentili   +4 more
wiley   +1 more source

TARDBP (TDP‐43) Knock‐in Zebrafish Display a Late‐Onset Motor Phenotype and Loss of Large Spinal Cord Motor Neurons

open access: yesAnnals of Neurology, EarlyView.
Objective Mutations in TARDBP (encoding TDP‐43) are associated with the neurodegenerative disease amyotrophic lateral sclerosis (ALS) and include familial missense mutations where there are a lack of models and mechanisms examining how they are pathogenic.
Ziyaan A. Harji   +10 more
wiley   +1 more source

The effect of diets low in choline

open access: green, 1936
C. H. Best   +3 more
openalex   +2 more sources

Metabolism‐Regulating Nanomedicines for Cancer Therapy

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review highlights metabolism‐regulating nanomedicines designed to target glycolytic, lipid, amino acid, and nucleotide pathways in tumors. By incorporating metabolism‐regulating agents into versatile nanocarriers such as liposomes, micelles, dendrimers, and engineered bacteria, these platforms achieve targeted delivery, controlled release ...
Xiao Wu, Shiyi Geng, Jian Yang
wiley   +1 more source

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