Results 201 to 210 of about 1,083,054 (280)

Modulation of KATP channels by diazoxide preserves mitochondrial function and barrier integrity under staurosporine‐induced epithelial stress

British Journal of Pharmacology, EarlyView.
Background and Purpose Intestinal barrier dysfunction caused by mitochondrial stress, oxidative damage and apoptosis, are hallmarks of dysbiosis‐associated gastrointestinal (GI) disorders. Staurosporine causes downstream features of dysbiosis‐induced epithelial damage.
Fatima Maqoud, Eleonora Malerba, Simona Drago, Antonella Orlando, Domenica Mallardi, Nicoletta De Lucia, Marina Antonacci, Annamaria Di Turi, Domenico Tricarico, Francesco Russo   +9 more
wiley   +1 more source

Cannabidiol and cannabigerol ameliorate steatotic liver disease via phosphocreatine buffering and lysosomal restoration

British Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) and cannabigerol (CBG) alleviate hepatic steatosis in obese mice by shifting energy buffering towards phosphocreatine and enhancing lysosomal lipid degradation and trafficking. These effects are associated with increased creatine kinase activity and lysobisphosphatidic acid (LBPA) levels, highlighting a previously unrecognised ...
Radka Kočvarová, Shahar Azar, Bella Agranovich, Ifat Abramovich, Saveliy Kirillov, Alina Nemirovski, Saja Baraghithy, Inbar Plaschkes, Emmanuelle Merquiol, Alexander Rouvinski, Galia Blum, Liad Hinden, Joseph Tam   +12 more
wiley   +1 more source

Dietary methionine/choline deficiency affects behavioural and molecular circadian rhythms

Saer B, Taylor G, Hayes A, Ananthasubramaniam B, Fustin J.   +4 more
europepmc   +1 more source

Systems biology insights into the molecular drivers of childhood stunting and implications for intervention. [PDF]

Front Nutr
Dable-Tupas G, Maraon ABA, Bernolo LJL, Toñacao NGF, Taylaran ADM, Plata MAC, Alcano JC, Björvang RD, Zain SM, Kobayashi V, Arefayine MB, Toni AT, Nacis JS, Gonzales GB.   +13 more
europepmc   +1 more source

Spectral Characterization of the Life Stages and Physiological Responses of Diatraea saccharalis Fabricius (Lepidoptera: Crambidae) Larvae Parasitized by Cotesia flavipes Cameron (Hymenoptera: Braconidae)

Entomologia Experimentalis et Applicata, EarlyView.
Hyperspectral proximal sensing was used to characterize the life stages and physiological responses of Diatraea saccharalis and to detect parasitism by Cotesia flavipes. Distinct spectral signatures differentiated eggs, larval instars, pupae, and adults, as well as live, dead, and parasitized larvae.
Souradji I. Bachirou, David L. Rosalen, Sergio A. De Bortoli, Pedro G. Peixoto   +3 more
wiley   +1 more source

Novel insights into choline's role in promoting myofiber hypertrophy and mitochondrial function in muscle of sub-adult grass carp (<i>Ctenopharyngodon idella</i>). [PDF]

Anim Nutr
Li Q, Zhou X, Feng L, Jiang W, Liu Y, Ma Y, Kuang S, Li S, Tang L, Zhong C, Wu P.   +10 more
europepmc   +1 more source

Sacubitril/Valsartan Attenuates Inflammation and Fibrosis Associated With Decreased Integrin α8 and Inhibits Hepatocarcinogenesis in a Rat Model of Metabolic Dysfunction‐Associated Steatohepatitis

Hepatology Research, EarlyView.
Sacubitril/Valsartan (Sac/Val) alleviates fibrosis and inflammation in metabolic dysfunction‐associated steatohepatitis (MASH). Its anti‐fibrotic effect is linked to the suppression of Integrin alpha 8 (Itga8), a protein crucial for hepatic stellate cell (HSC) activation and collagen production.
Hayato Kawamura, Aya Naiki‐Ito, Xiaochen Kuang, Akihiro Murakami, Masayuki Komura, Takanori Suzuki, Hiroyuki Kato, Yuko Nagayasu, Kentaro Matsuura, Kei Fujiwara, Hiromi Kataoka, Satoru Takahashi   +11 more
wiley   +1 more source

Perinatal nutrition as a key regulator of genomic imprinting: a new paradigm for maternal-child health. [PDF]

Front Nutr
Aronica L, Fessler SN, Stone Rydbom E, Jirtle RL.   +3 more
europepmc   +1 more source

Dietary Garlic Powder Supplementation Could Ameliorate Unfavorable Effects of Choline Deficiency on the Liver Health and Immune System of Broiler Chickens [PDF]

, 2019
Bahman Navidshad, Z Maghsoodi, Saeid Nikbin, Ali Kalantari‐Hesari   +3 more
openalex  

Steatotic Liver Disease: A Key Related Risk Factor in the Emergence of Metabolic Syndrome‐Related Disorders

Hepatology Research, EarlyView.
It is speculated that the onset of obesity‐related diseases follows the sequence of obesity → SLD → MetS‐related diseases. In this study, the contribution of SLD to each MetS‐related disease was large for T2D and hypertension and SLD contributed to the onset and new onset of the disease by the 7‐year follow‐up.
Yoshihiro Kamada, Makoto Fujii, Hitoshi Nishizawa, Shiro Fukuda, Makoto Yamada, Iichiro Shimomura, Eiji Miyoshi   +6 more
wiley   +1 more source