Results 31 to 40 of about 59,547 (299)
Journal of Nutritional Science, 2023 Choline was recently established as an essential nutrient for Atlantic salmon at all life stages. Choline deficiency is manifested as an excessive accumulation of dietary fat within the intestinal enterocytes, a condition known as steatosis.
Daphne Siciliani +4 more
doaj +1 more source
High dietary folate in pregnant mice leads to pseudo-MTHFR deficiency and altered methyl metabolism, with embryonic growth delay and short-term memory impairment in offspring [PDF]
, 2017 Methylenetetrahydrofolate reductase (MTHFR) generates methyltetrahydrofolate for methylation reactions. Severe MTHFR deficiency results in homocystinuria and neurologic impairment.
Bahous, RH +13 more
core +1 more source
LIVER LIPIDS OF CHOLINE-DEFICIENT RATS [PDF]
Biochemical Journal, 1965 1. Four-week-old male and female rats were given choline-deficient diets for 2 weeks. Deficient animals gained nearly as much weight as normal controls of the same sex. 2. The amounts of triglyceride and esterified cholesterol in liver lipids were increased threefold or more by the deficiency.
J, TINOCO +4 more
openaire +2 more sources
Gender Differences in Bile Acids and Microbiota in Relationship with Gender Dissimilarity in Steatosis Induced by Diet and FXR Inactivation. [PDF]
, 2017 This study aims to uncover how specific bacteria and bile acids (BAs) contribute to steatosis induced by diet and farnesoid X receptor (FXR) deficiency in both genders.
French, Samuel W +8 more
core +1 more source
Journal of Dairy Science, 2023 : Rumen-protected choline (RPC) supplementation in the periparturient period has in some instances prevented and alleviated fatty liver disease in dairy cows. Mechanistically, however, it is unclear how choline prevents the accumulation of lipid droplets
Wenyan Lu +8 more
doaj +1 more source
Potential therapeutic use of the ketogenic diet in autism spectrum disorders. [PDF]
, 2014 The ketogenic diet (KGD) has been recognized as an effective treatment for individuals with glucose transporter 1 (GLUT1) and pyruvate dehydrogenase (PDH) deficiencies as well as with epilepsy.
Dueñas, Nadia +2 more
core +1 more source
The Lysophospholipase PNPLA7 Controls Hepatic Choline and Methionine Metabolism
Biomolecules, 2023 The in vivo roles of lysophospholipase, which cleaves a fatty acyl ester of lysophospholipid, remained unclear. Recently, we have unraveled a previously unrecognized physiological role of the lysophospholipase PNPLA7, a member of the Ca2+-independent ...
Sayaka Harada +8 more
doaj +1 more source
Journal of Pharmacological Sciences, 2016 We examined the functional characteristics of choline uptake in human tongue carcinoma using the cell line HSC-3. Furthermore, we explored the possible correlation between the inhibition of choline uptake and apoptotic cell death.
Ryohta Nishiyama +8 more
doaj +1 more source
Vitamin D and Disease Severity in Multiple Sclerosis-Baseline Data From the Randomized Controlled Trial (EVIDIMS) [PDF]
, 2020 Objective: To investigate the associations between hypovitaminosis D and disease activity in a cohort of relapsing remitting multiple sclerosis (RRMS) and clinically isolated syndrome (CIS) patients.
Bellmann-Strobl, Judith +7 more
core +2 more sources
Cells, 2022 High-fat diets (HFD) lead to impairment of chylomicrons (CMs) assembly and adversely influence intestinal lipid homeostasis. However, the mechanisms of HFD impairing CMs assembly have yet to be fully understood. Additionally, although choline, as a lipid-
Zhen-Yu Bai +5 more
doaj +1 more source