Results 161 to 170 of about 286,434 (357)
Activities of enzymes of the cholinergic systems in the guinea pig cochlea. [PDF]
Donald A. Godfrey +2 more
openalex +1 more source
Addressing complexity in the study of life sciences through Systems Biology and Systems Medicine has been transformative, making Systems Pharmacology the next logical step. In this review, we focus on physical stimuli, whose potential in pharmacology has been neglected, despite demonstrated therapeutic properties.
Veronica Paparozzi +10 more
wiley +1 more source
Actions of Cholinergic Pharmacological Agents on the Cell Body Membrane of the Fast Coxal Depressor Motoneurone of the Cockroach (Periplaneta Americana) [PDF]
Jonathan David, David B. Sattelle
openalex +1 more source
Functional impact of cholinergic dysfunction on retrosplenial circuits in the 5xFAD mouse model of Alzheimer’s disease [PDF]
Izabela Jedrasiak‐Cape, Omar J. Ahmed
openalex +1 more source
Theorized mechanism of dopamine homeostasis restoration in the nucleus accumbens core induced by a psychedelic intervention. Abstract Psychedelics have garnered great attention in recent years as treatments for major depressive disorder (MDD) and treatment‐resistant depression because of their ability to alter consciousness and afflicted cognitive ...
Lucas Wittenkeller +3 more
wiley +1 more source
Profiling Basal Forebrain Cholinergic Neurons Reveals a Molecular Basis for Vulnerability Within the Ts65Dn Model of Down Syndrome and Alzheimer’s Disease [PDF]
Melissa J. Alldred +5 more
openalex +1 more source
Evaluation of preclinical antipsychotic models used to support first‐in‐human clinical trials
Abstract Schizophrenia is regarded as a complex and heterogeneous psychiatric disorder, characterised by diverse symptoms and comorbidities, which complicate both clinical management and drug development. Current pharmacological treatment, primarily based on dopamine D2 receptor antagonism or partial agonism, which has not markedly progressed since the
Thi Viet Ha Nguyen +2 more
wiley +1 more source
A role for epithelium‐derived 6‐nitrodopamine on human ureter contractility
Abstract Background and Purpose To investigate the basal release of 6‐nitrodopamine (6‐ND) from human isolated ureter and the role of this novel catecholamine in the ureter contractility. Experimental Approach Ureters from 67 brain‐dead organ donors (40 males and 27 females) were used during kidney transplantation procedures.
Wilmar Azal Neto +12 more
wiley +1 more source

