Characterizing the Access of Cholinergic Antagonists to Efferent Synapses in the Inner Ear [PDF]
Frontiers in Neuroscience, 2021 Stimulation of cholinergic efferent neurons innervating the inner ear has profound, well-characterized effects on vestibular and auditory physiology, after activating distinct ACh receptors (AChRs) on afferents and hair cells in peripheral endorgans ...
Choongheon Lee +8 more
doaj +2 more sources
Cholinergic Antagonists and Behavioral Disturbances in Neurodegenerative Diseases. [PDF]
Int J Mol Sci, 2023 Cholinergic antagonists interfere with synaptic transmission in the central nervous system and are involved in pathological processes in patients with neurocognitive disorders (NCD), such as behavioral and psychological symptoms of dementia (BPSD). In this commentary, we will briefly review the current knowledge on the impact of cholinergic burden on ...
Mahmoudi R +6 more
europepmc +4 more sources
Effects of cholinergic antagonists on ghrelin release and expression in the crop, proventriculus, and duodenum of newly hatched chickens [PDF]
Frontiers in PhysiologyThe aim of this study was to evaluate the effect of the cholinergic receptor antagonists on ghrelin (GHRL) expression and release from parts of the gastrointestinal system in an unique animal model—newly hatched chickens.
Colin Guy Scanes +2 more
doaj +2 more sources
Effects of Cholinergic and Opioid Antagonists on In Vitro Release of Met-Enkephalin, Somatostatin and Insulin-like Growth Factor-1 by and PENK Expression in Crop, Proventriculus and Duodenum of Newly Hatched Chickens [PDF]
AnimalsThe gastrointestinal (GI) tract is under neural, endocrine and paracrine control. The release (basal and in the presence of either cholinergic and opioid antagonists) of Met-enkephalin, insulin-like growth factor 1 (IGF-1) and somatostatin (SRIF) was ...
Colin G. Scanes +3 more
doaj +2 more sources
Cholinergic System and Its Therapeutic Importance in Inflammation and Autoimmunity
Frontiers in Immunology, 2021 Neurological and immunological signals constitute an extensive regulatory network in our body that maintains physiology and homeostasis. The cholinergic system plays a significant role in neuroimmune communication, transmitting information regarding the ...
Namrita Halder, Girdhari Lal
doaj +1 more source
Frontiers in Immunology, 2021 The cholinergic system is present in both bacteria and mammals and regulates inflammation during bacterial respiratory infections through neuronal and non-neuronal production of acetylcholine (ACh) and its receptors.
Leon Islas-Weinstein +9 more
doaj +1 more source
Oxybutynin as an alternative treatment for hyperhidrosis [PDF]
Anais Brasileiros de Dermatologia, 2017 : Hyperhidrosis is the excessive production of sweating, which can be primary and focal or secondary to various pathologies. The exact cause of primary focal hyperhidrosis is still unknown, although a genetic basis is recognized, and its prevalence ...
Sergio Delort +2 more
doaj +1 more source
Efficacy of Anticholinergics for Chronic Prostatitis/Chronic Pelvic Pain Syndrome in Young and Middle-Aged Patients: A Single-Blinded, Prospective, Multi-Center Study [PDF]
International Neurourology Journal, 2011 Purpose Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) exhibits variable lower urinary tract symptoms (LUTS). The aim of this study was to evaluate the incidence of LUTS and the efficacy of an anticholinergic agent in young and middle-aged CP/
Doo Sang Kim +4 more
doaj +1 more source
Brain Stimulation, 2023 Background: We previously found that vagus nerve stimulation (VNS) strengthened stimulus-evoked activity in the superficial layer of the sensory cortex but not in the deep layer, suggesting that VNS altered the balance between the feedforward (FF) and ...
Shinichi Kumagai +7 more
doaj +1 more source
PLoS ONE, 2021 Cholinergic modulation of hippocampal network function is implicated in multiple behavioral and cognitive states. Activation of nicotinic and muscarinic acetylcholine receptors affects neuronal excitability, synaptic transmission and rhythmic ...
Olha Zapukhliak +7 more
doaj +1 more source