Results 161 to 170 of about 126,705 (239)

Synergistic Effect of Hesperidin, Acarbose, and Exercise Combination on Neuroinflammation and Neurochemical Alterations in Diabetic Encephalopathy Rat Model

Food Chemistry International, Volume 2, Issue 2, Page 263-273, June 2026.
Diabetic encephalopathy (DME) impairs neurobehavior, neurochemicals, oxidative stress, and inflammation. This study evaluated the effects of hesperidin (HSP), exercise (EX), and acarbose (ACA) alone or combined on diabetic rats. Treatments reduced AChE, BChE, ACE, arginase, ATPDase, 5′‐nucleotidase, ADA, LDH, TBARS, and ROS, while increasing IL‐10, SOD,
Idowu Sunday Oyeleye, Olajide Raymond Ojo, Taiwo Olawale Adeleke, Adeyinka Sunday Ajeigbe, Mercy Gladys Tenywa, Oboh Ganiyu   +5 more
wiley   +1 more source

The Cholinergic Anti-Inflammatory Pathway Attenuates the Development of Atherosclerosis in Apoe^-/- Mice through Modulating Macrophage Functions. [PDF]

Biomedicines, 2021
Qian Z, Yang H, Li H, Liu C, Yang L, Qu Z, Li X.   +6 more
europepmc   +1 more source

Potential of Aeginetia indica for Alzheimer's Disease Management: In Vitro, In Vivo, and Computational Insights

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
MeOH extract of Aeginetia indica (AİME); chromatographic study: LCMS/MS and GCMS; in vitro assays: AChE assays → ↓ AChE level, ↓ inflammation level and antioxidant assays → ROS; in vivo anti‐inflammatory study: ↓ inflammation level; molecular docking → molecular dynamics simulations: acacetin and acteoside.
Marjanur Rahman Bhuiyan, Md. Sharif Reza, Sadikur Rahman Shuvo, Mustafa Abdullah Yilmaz, Syed Mumtahin Mannan Siam, Md. Shadman Sakib, Oguz Cakir, Md. Nazmul Islam Durjoy, Abbas Tarhan, Nuraniye Eruygur, A. F. M. Shahid Ud Daula   +10 more
wiley   +1 more source

Association of the Cholinergic Anti-Inflammatory Pathway Activity with Proinflammatory Factors and Prognosis of Patients with Acute Respiratory Distress Syndrome.

Evid Based Complement Alternat Med, 2022
Yang Y, Zhang J, Yang X, Yang J.
europepmc   +1 more source

Activation of the Cholinergic Anti-inflammatory Pathway Attenuated Angiotension II-Dependent Hypertension and Renal Injury. [PDF]

Front Pharmacol, 2021
Wu SJ, Shi ZW, Wang X, Ren FF, Xie ZY, Lei L, Chen P.   +6 more
europepmc   +1 more source

The Role of Endothelin‐1 in Autoimmune Diseases: Mechanistic Insights and Therapeutic Targets

iNew Medicine, Volume 2, Issue 2, June 2026.
The Role of Endothelin‐1 in Autoimmune Diseases. NF‐κB: nuclear factor kappa‐B; MAPK: mitogen‐activated protein kinase; PI3K: phosphoinositide 3‐kinase; ROS: reactive oxygen species; CTGF: connective tissue growth factor; TGF‐β: transforming growth factor‐β.
Xun Gong, Zhenyu Wang, Suyin Yang, Kaige Gao, Xin Yang, Min Tang   +5 more
wiley   +1 more source

Innovative Drug Delivery Systems for the Treatment of Glaucoma

MedComm – Biomaterials and Applications, Volume 5, Issue 2, June 2026.
This review aims to provide a comprehensive overview of current topical drug delivery strategies for ocular hypotensive agents in glaucoma therapy. Additionally, it discusses the potential impact of emerging nanotechnological and biomaterial‐based systems in shaping the future of ophthalmic drug delivery, with an emphasis on enhancing efficacy, safety,
Jing Chu, Junzhi Li, Zhenlin Chen, Jinyu Zhang, Siqi Feng, Jiaying Huang, Yawen Chu, Xue Zhou, Wei Wang, Shangsi Chen   +9 more
wiley   +1 more source

Quantification of Acetylcholine Release from Splenocytes for Exploration of the Cholinergic Anti-Inflammatory Pathway

, 2019
Introduction. Inflammation is characterized by complex interactions between pro- and anti- inflammatory cytokines. Recent research has probed the role of the nervous system in inflammation, part of which includes the cholinergic anti-inflammatory ...
Lawson, Sarah, Hoover, Donald, Brown, Stacy   +2 more
core   +1 more source

Circadian Immunity and Vascular Inflammation in Cardiovascular Disease Chronotherapy Windows: Time for a Re‐Assessment

Med Research, Volume 2, Issue 2, Page 236-279, June 2026.
ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang, Ge Zhang, Tian‐Ding Liu, Tianshu Gu, Fengyi Yu, Pengyuan Xu, Wunan Mi, Xuanjiang Zhao, Qian Guo, Honglin Zheng, Taiqi Zhao, Qiang Li, Di Lu, Mingxuan Duan, Chaoyang Yu, Ruhao Wu, Shiqian Zhang, Haonan Zhang, Zeyu Wang, Youyang Zheng, Yan Xiao, Zenglei Zhang, Ge Zhang   +22 more
wiley   +1 more source

Klotho microinjection into the RVLM attenuates acute kidney injury <i>via</i> interaction with the cholinergic anti-inflammatory pathway in rats. [PDF]

Res Pharm Sci
Ahmadi F, Amohashemi E, Kazemi M, Salehi H, Reisi P.   +4 more
europepmc   +1 more source