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A basic solution to activate the cholinergic anti-inflammatory pathway via the mesothelium? [PDF]
Pharmacol Res, 2019 Mannon EC +6 more
europepmc +1 more source
Ultrasound improves the outcomes of cardiopulmonary resuscitation in rats by stimulating the cholinergic anti‑inflammatory pathway. [PDF]
Mol Med Rep, 2019 Zhang Y +6 more
europepmc +1 more source
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The cholinergic anti-inflammatory pathway
Brain, Behavior, and Immunity, 2005The regulation of the innate immune response is critical for controlling inflammation and for the prevention and treatment of diseases. We recently demonstrated that the efferent vagus nerve inhibits pro-inflammatory cytokine release and protects against systemic inflammation, and termed this vagal function "the cholinergic anti-inflammatory pathway ...
Valentin A Pavlov, Kevin J. Tracey
exaly +3 more sources
The role of the cholinergic anti-inflammatory pathway in autoimmune rheumatic diseases [PDF]
Scandinavian Journal of Immunology, 2021 AbstractThe cholinergic anti‐inflammatory pathway (CAP) is a classic neuroimmune pathway, consisting of the vagus nerve, acetylcholine (ACh)—the pivotal neurotransmitter of the vagus nerve—and its receptors. This pathway can activate and regulate the activities of immune cells, inhibit cell proliferation and differentiation, as well as suppress ...
Jiaqi Lv, Xiaoxiao Ji, Huiqin Hao
exaly +3 more sources
Cholinergic Anti-inflammatory Pathway and Stroke
Current Drug Delivery, 2017Stroke is devastating cerebrovascular event which is responsible for 6.7 million deaths each year worldwide. Inflammation plays an important role in the pathophysiology of stroke. Targeting inflammation after stroke is highly actual topic for both experimental and clinical research.Research articles related to cholinergic anti-inflammatory pathway ...
Kamil Duris, Michal Jurajda
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Modulation of preeclampsia by the cholinergic anti-inflammatory pathway: Therapeutic perspectives
Biochemical Pharmacology, 2021The cholinergic anti-inflammatory pathway (CAP) is vital for the orchestration of the immune and inflammatory responses under normal and challenged conditions. Over the past two decades, peripheral and central circuits of CAP have been shown to be critically involved in dampening the inflammatory reaction in a wide array of inflammatory disorders ...
Mahmoud M El-Mas +2 more
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Neuro-immune interactions via the cholinergic anti-inflammatory pathway [PDF]
Life Sciences, 2007 The overproduction of TNF and other cytokines is associated with the pathophysiology of numerous diseases. Controlling cytokine synthesis and release is critical for preventing unrestrained inflammation and maintaining health. Recent studies identified an efferent vagus nerve-based mechanism termed "the cholinergic anti-inflammatory pathway" that ...
Valentin A Pavlov +1 more
exaly +3 more sources
The role of the cholinergic anti-inflammatory pathway in septic cardiomyopathy
International Immunopharmacology, 2021Septic cardiomyopathy (SCM)is common in septic patients and results in cardiovascular failure. The pathogenesis of SCM is complicated, and patients with SCM have high mortality because current treatment methods are limited. The cholinergic anti-inflammatory pathway (CAP) modulates inflammatory responses through vagus nerve stimulation that leads to the
Wenting Wang +4 more
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Cholinergic anti-inflammatory pathway and connective tissue diseases
Inflammopharmacology, 2021Connective tissue diseases (CTDs) consist of an extensive range of heterogeneous medical conditions, which are caused by immune-mediated chronic inflammation and influences the various connective tissues of the body. They include rheumatoid arthritis, systemic lupus erythematosus, systemic sclerosis, vasculitis, Sjögren's syndrome, Behcet's disease ...
Khalil Hajiasgharzadeh +6 more
openaire +2 more sources