Results 201 to 210 of about 126,705 (239)
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The cholinergic anti-inflammatory pathway in humans: State-of-the-art review and future directions

Neuroscience and Biobehavioral Reviews, 2022
The parasympathetic nervous system modulates inflammation through efferent vagus nerve signaling. Tracey (2002) termed this process as the cholinergic anti-inflammatory pathway (CAP).
Nicholas V Alen
exaly   +2 more sources

Structurally diverse steroids from an endophyte of Aspergillus tennesseensis 1022LEF attenuates LPS-induced inflammatory response through the cholinergic anti-inflammatory pathway

Chemico-Biological Interactions, 2022
The emerging cholinergic anti-inflammatory pathway plays a key role in regulating inflammation. Steroids are known to possess remarkable anti-inflammatory activity.
Jun-Cheng Su, Xingyuan Xu, Xia Wei
exaly   +2 more sources

The Role of α7nAChR-Mediated Cholinergic Anti-inflammatory Pathway in Immune Cells

Inflammation, 2021
Alpha 7 nicotinic acetylcholine receptor (α7nAChR) is widely distributed in the nervous and non-cholinergic immune systems. It is necessary for the cholinergic transmitter to participate in the regulation of inflammatory response and is the key element of cholinergic anti-inflammatory pathway (CAP).
Yi-jin Wu   +5 more
openaire   +3 more sources

Cholinergic Anti-inflammatory Pathway and Stroke

Current Drug Delivery, 2017
Stroke is devastating cerebrovascular event which is responsible for 6.7 million deaths each year worldwide. Inflammation plays an important role in the pathophysiology of stroke. Targeting inflammation after stroke is highly actual topic for both experimental and clinical research.Research articles related to cholinergic anti-inflammatory pathway ...
Kamil Duris, Michal Jurajda
exaly   +3 more sources

The role of the cholinergic anti-inflammatory pathway in septic cardiomyopathy

International Immunopharmacology, 2021
Septic cardiomyopathy (SCM)is common in septic patients and results in cardiovascular failure. The pathogenesis of SCM is complicated, and patients with SCM have high mortality because current treatment methods are limited. The cholinergic anti-inflammatory pathway (CAP) modulates inflammatory responses through vagus nerve stimulation that leads to the
Megan Molnár
exaly   +3 more sources

The cholinergic anti-inflammatory pathway: towards innovative treatment of rheumatoid arthritis

open access: yesNature Reviews Rheumatology, 2009
The efferent vagus nerve can regulate inflammation via its principal neurotransmitter acetylcholine (ACh), a concept referred to as the 'cholinergic anti-inflammatory pathway'. ACh interacts with members of the nicotinic acetylcholine receptor (nAChR) family, in particular with the alpha7 subunit (alpha7nAChR), which is expressed not only by neurons ...
van Maanen, Marjolein A.   +2 more
openaire   +3 more sources

Targeting the cholinergic anti-inflammatory pathway: an innovative strategy for treating diseases

Molecular Biology Reports
The cholinergic anti-inflammatory pathway (CAP) is comprised of the vagus nerve, acetylcholine, nicotinic acetylcholine receptors, the spleen, and the splenic nerve. It represents a sophisticated neuroimmune axis that critically regulates the crosstalk between the nervous system and the immune response via the vagus nerve.
Yifan, Li, Shufan, Ding, Yongjie, Wang
openaire   +3 more sources

Electro-acupuncture regulates the cholinergic anti-inflammatory pathway in a rat model of chronic obstructive pulmonary disease

Journal of Integrative Medicine, 2018
OBJECTIVE Acupuncture has a definite therapeutic effect on chronic obstructive pulmonary disease (COPD), and the cholinergic anti-inflammatory pathway (CAP) has been shown to be involved in regulation of inflammation.
Zi-Bing Liu
exaly   +2 more sources

Acetylcholinesterase inhibitors targeting the cholinergic anti-inflammatory pathway: a new therapeutic perspective in aging-related disorders

open access: yesAging Clinical and Experimental Research, 2019
Neuroinflammation and cholinergic dysfunction, leading to cognitive impairment, are hallmarks of aging and neurodegenerative disorders, including Alzheimer’s disease (AD).
R. Benfante   +3 more
semanticscholar   +2 more sources

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