Results 221 to 230 of about 126,705 (239)
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Spikeotherapeutics: the Cholinergic Anti-inflammatory Pathway, Dysautonomia, Chronic Sympathetic Nervous System Activation and Nicotine: A Possible Way Forward.

Medical Research Archives
(1) Background: Severe COVID-19 is characterised by immune dysregulation and a highly inflammatory cytokine storm with symptoms of dysautonomia. It has been proposed that this is at least partially a result of dysregulation of the cholinergic anti ...
Robyn Cosford
semanticscholar   +1 more source

Berberine Ameliorates Glucose Metabolism in Diabetic Rats through the alpha7 Nicotinic Acetylcholine Receptor-Related Cholinergic Anti-Inflammatory Pathway

Planta Medica, 2021
Berberine is an isoquinoline derivative alkaloid extracted from Chinese herbs. Recent studies have demonstrated the therapeutic effect of berberine on glucose metabolic disorders. However, its specific mechanism is still unclear.
Ding-kun Wang   +8 more
semanticscholar   +1 more source

Electroacupuncture Ameliorates Intestinal Barrier Destruction in Mice With Bile Duct Ligation-Induced Liver Injury by Activating the Cholinergic Anti-Inflammatory Pathway.

Neuromodulation (Malden, Mass.), 2022
OBJECTIVES Electroacupuncture (EA) at Zusanli (ST36) can attenuate inflammation in different rodent models. However, the therapeutic mechanisms underlying its action in inhibiting intestinal barrier destruction and liver injury in cholestasis mice have ...
Wei Lei   +4 more
semanticscholar   +1 more source

Identification of O-arylated huperzinines as novel cholinergic anti-inflammatory pathway agonists against gout arthritis.

Bioorganic chemistry (Print)
Lycodine alkaloids are important natural products with diverse biological effects. In this manuscript, we set out the first structural optimization of the 2-pyridone moiety of Lycodine alkaloid via selective O-arylation under metal-free conditions and ...
Hao Wu   +9 more
semanticscholar   +1 more source

Osthole Activates the Cholinergic Anti‐Inflammatory Pathway via α7nAChR Upregulation to Alleviate Inflammatory Responses

Chemistry and Biodiversity
Osthole (also known as Osthol) is the main anti‐inflammatory coumarin found in Cnidium monnieri and severs as the exclusive quality‐controlled component according the Chinese Pharmacopoeia.
Shu‐Hang Li   +7 more
semanticscholar   +1 more source

Lactobacillus helveticus R0052-derived membrane vesicles ameliorate DSS-induced inflammatory bowel disease by modulating the gut microbiota and activating the cholinergic anti-inflammatory pathway.

International Immunopharmacology
Inflammatory bowel disease (IBD) involves persistent immune dysregulation in the gut, accompanied by changes in microbiota and metabolite profiles.
C. V. Olovo   +4 more
semanticscholar   +1 more source

The cholinergic anti‐inflammatory pathway: an innovative treatment strategy for respiratory diseases and their comorbidities

Current opinion in pharmacology (Print), 2018
HighlightsThe cholinergic anti‐inflammatory pathway modulates inflammatory responses.The &agr;7nAChR is the critical target on inflammatory cells in this pathway.Recent studies newly revealed neuron‐ILC2s interactions in allergic inflammation.Neuroimmune
M. Yamada, M. Ichinose
semanticscholar   +1 more source

Sevoflurane-induced inflammation development: involvement of cholinergic anti-inflammatory pathway

Behavioural Pharmacology, 2019
Chronic inflammation plays an important role in the mechanisms underpinning the development of anesthesia-induced cognitive dysfunction. However, less is known about how anesthesia causes inflammation. One possibility is that the inflammation is related to alteration of the activity of the alpha 7 nicotinic acetylcholine receptor cholinergic anti ...
Jian, Yin   +6 more
openaire   +2 more sources

The Cholinergic Anti-inflammatory Pathway: Connecting the Mind and Body

2006
As reviewed above, there is abundant evidence implicating autonomic dysfunction or cytokine excess in diseases with inflammatory pathology such as sepsis, Crohn’s disease, and rheumatoid arthritis. The identification of a vagus nerve mechanism that regulates cytokine activity and immune cell activation now suggests that some neurological or nervous ...
C. J. Czura   +2 more
openaire   +1 more source

Activation of cholinergic anti-inflammatory pathway involved in therapeutic actions of α-mangostin on lipopolysaccharide-induced acute lung injury in rats

International Journal of Immunopathology and Pharmacology, 2020
Opeyemi Joshua Olatunji   +2 more
exaly  

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