Results 211 to 220 of about 126,705 (239)

Cholinergic anti-inflammatory pathway and connective tissue diseases

Inflammopharmacology, 2021
Connective tissue diseases (CTDs) consist of an extensive range of heterogeneous medical conditions, which are caused by immune-mediated chronic inflammation and influences the various connective tissues of the body. They include rheumatoid arthritis, systemic lupus erythematosus, systemic sclerosis, vasculitis, Sjögren's syndrome, Behcet's disease ...
Khalil Hajiasgharzadeh, Alireza Khabbazi, Ahad Mokhtarzadeh, Amir Baghbanzadeh, Zahra Asadzadeh, Elham Adlravan, Behzad Baradaran   +6 more
openaire   +2 more sources

Cholinergic anti-inflammatory pathway mediates diesel exhaust PM2.5-induced pulmonary and systemic inflammation.

Journal of Hazardous Materials, 2023
Previous research has indicated that the cholinergic anti-inflammatory pathway (CAP) can regulate the duration and intensity of inflammatory responses.
Yuanting Xie, Shimin Tao, Bin Pan, Wenhui Yang, Wenpu Shao, Xinyi Fang, Dongyang Han, Jingyu Li, Yubin Zhang, Renjie Chen, Weihua Li, Yanyi Xu, H. Kan   +12 more
semanticscholar   +1 more source

Cholinergic anti-inflammatory pathway in intracerebral hemorrhage

Brain Research, 2010
Stimulated vagus nerve excretes acetylcholine into the peripheral immune organs such as the spleen, reducing innate inflammation. Here, we investigated whether activation of this "cholinergic anti-inflammatory pathway" can be used to reduce cerebral inflammation in a model of hemorrhagic stroke.
Lee, ST Lee, Soon-Tae, Chu, K Chu, Kon, Jung, KH Jung, Keun-Hwa, Kang, KM Kang, Kyung-Mook, Kim, JH Kim, Jin-Hee, Bahn, JJ Bahn, Jae-Joon, Jeon, D Jeon, Daejong, Kim, M Kim, Manho, Lee, SK Lee, Sang Kun, Roh, JK Roh, Jae-Kyu   +9 more
openaire   +3 more sources

Controlling inflammation: the cholinergic anti-inflammatory pathway

Biochemical Society Transactions, 2006
Innate immune responses and inflammation are regulated in part by neural mechanisms. In the present paper, we summarize experimental evidence that reveals that innate immunity and inflammation are controlled by the vagus nerve, previously known as a regulator of other vital physiological functions.
V A, Pavlov, K J, Tracey
openaire   +2 more sources

The Effect of the Cholinergic Anti‐Inflammatory Pathway on Experimental Colitis

Scandinavian Journal of Immunology, 2007
AbstractInflammatory bowel diseases (IBD) are characterized by proinflammatory cytokines, tissue damage and loss of neuron in inflamed mucosa, which implies the cholinergic anti‐inflammatory pathway may be destroyed during the process of inflammatory response.
A, Bai, Y, Guo, N, Lu
openaire   +3 more sources

MicroRNA: Novel Modulators of the Cholinergic Anti-Inflammatory Pathway

Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry, 2013
MicroRNAs (miRNAs) have emerged as key gene regulators controlling the expression of many target mRNAs. The nervous system harbors highest number of miRNAs expressed in a spatially and temporally controlled manner.
Medha, Priyadarshini, N A, Arivarasu, Aaliya, Shah, Shams, Tabrez, Shubha, Priyamvada, Mohd, Aatif   +5 more
openaire   +2 more sources

Neural inhibition of inflammation: the cholinergic anti-inflammatory pathway

Journal of Endotoxin Research, 2003
The innate immune system is activated by infection and injury to release pro-inflammatory cytokines, which activate macrophages and neutrophils and modulate specific cellular responses. The magnitude of the cytokine response is critical, because a deficient response may result in secondary infections, while an excessive response may be more injurious ...
Christopher J, Czura, Steven G, Friedman, Kevin J, Tracey   +2 more
openaire   +2 more sources

Exploring the Potential Role of the Cholinergic Anti-Inflammatory Pathway from the Perspective of Sepsis Pathophysiology

Journal of Intensive Care Medicine
Sepsis is one of the most prevalent conditions in critical care medicine and is characterized by a high incidence, mortality, and poor prognosis, with no specific treatment currently available.
Ziyi Zhu, Lixia Liu
semanticscholar   +1 more source

The cholinergic anti-inflammatory pathway ameliorates acute viral myocarditis in mice by regulating CD4+ T cell differentiation

Virulence, 2018
Many studies have found that abnormalities in the proportion and differentiation of CD4+ T cells (Th cells) are closely related to the pathogenesis of viral myocarditis (VMC). Our previous research indicates that the cholinergic anti-inflammatory pathway
Lin Jia-Feng, Li Yue-Chun
exaly   +2 more sources

Acute Vagotomy Activates the Cholinergic Anti-Inflammatory Pathway

American Journal of Physiology-Heart and Circulatory Physiology, 2005
Within minutes of acute myocardial infarction (MI), proinflammatory cytokines increase in the brain, heart, and plasma. We hypothesized that cardiac afferent nerves stimulated by myocardial injury signal the brain to increase central cytokines. Urethane-anesthetized male Sprague-Dawley rats underwent ligation of the left anterior descending coronary ...
van Westerloo, David, van der Poll, Tom
openaire   +1 more source