Results 1 to 10 of about 1,005,680 (118)

A coordinated multi-target approach based on chondroitin sulphate nano-selenium mitigates Alzheimer’s disease pathologies in APP/PS1 mice [PDF]

Frontiers in Pharmacology
Alzheimer’s disease (AD) is a severe neurodegenerative disorder characterised by progressive memory loss and cognitive decline. Because of the lack of effective treatment modalities for AD, novel therapeutics that could delay the progression of AD are ...
Dongsheng Ji, Jing Zhao, Xinhui Huang, Xinhui Huang, Xuan Liu, Qirong Yang, Xinfeng Li, Lei Yan, Debo Gao, Yuliang Xiao   +9 more
doaj   +2 more sources

Multi‐label learning based target detecting from multi‐frame data

IET Image Processing, 2021
In the field of target detecting, lots of progress have been made in recent years. Owing to the progress of multiple frames time series data, or video satellites, target detecting from space‐borne satellite videos has been available. However, detecting a
Mengqing Mei, Fazhi He
doaj   +1 more source

Path Planning and Trajectory Optimization Based on Improved APF and Multi-Target

IEEE Access, 2023
Aiming at the shortcomings of the path generated by the artificial potential field (APF) method, such as local minimum, target unreachability, and low path smoothness, an improved artificial potential field method is proposed.
Jie Yang, Hongchang Zhang, Peng Ning
doaj   +1 more source

Synthesis and Biological Evaluation of Indole-2-Carboxamides with Potent Apoptotic Antiproliferative Activity as EGFR/CDK2 Dual Inhibitors

Pharmaceuticals, 2022
The apoptotic antiproliferative actions of our previously reported CB1 allosteric modulators 5-chlorobenzofuran-2-carboxamide derivatives VIIa–j prompted us to develop and synthesise a novel series of indole-2-carboxamide derivatives 5a–k, 6a–c, and 7 ...
Lamya H. Al-Wahaibi, Yaser A. Mostafa, Mostafa H. Abdelrahman, Ali H. El-Bahrawy, Laurent Trembleau, Bahaa G. M. Youssif   +5 more
doaj   +1 more source

Exploring Multifunctional Bioactive Components from Podophyllum sinense Using Multi-Target Ultrafiltration

Frontiers in Pharmacology, 2021
Podophyllum sinense (P. sinense) has been used as a traditional herbal medicine for ages due to its extensive pharmaceutical activities, including antiproliferative, anti-inflammatory, antiviral, insecticidal effects, etc.
Huixia Feng, Huixia Feng, Huixia Feng, Huixia Feng, Guilin Chen, Guilin Chen, Guilin Chen, Yongli Zhang, Yongli Zhang, Yongli Zhang, Mingquan Guo, Mingquan Guo, Mingquan Guo, Mingquan Guo   +13 more
doaj   +1 more source

Improving Ship Detection in Clutter-Edge and Multi-Target Scenarios for High-Frequency Radar

Remote Sensing, 2021
As one of the main sensors for continuous maritime measurements of sea state parameters, high-frequency surface wave radar (HFSWR) also plays an important role in ship detection and tracking.
Zhiqing Yang, Hao Zhou, Yingwei Tian, Weimin Huang, Wei Shen   +4 more
doaj   +1 more source

Target Localization Based on High Resolution Mode of MIMO Radar with Widely Separated Antennas

Remote Sensing, 2022
Coherent processing of multiple-input multiple-output (MIMO) radar with widely separated antennas has high resolution capability, but it also brings ambiguity in target localization.
Jiaxin Lu, Feifeng Liu, Hongjie Liu, Quanhua Liu   +3 more
doaj   +1 more source

Improved Mask R-CNN Multi-Target Detection and Segmentation for Autonomous Driving in Complex Scenes

Sensors, 2023
Vision-based target detection and segmentation has been an important research content for environment perception in autonomous driving, but the mainstream target detection and segmentation algorithms have the problems of low detection accuracy and poor ...
Shuqi Fang, Bin Zhang, Jingyu Hu
doaj   +1 more source

LncRNAs in hepatocellular carcinoma: molecular drivers and emerging therapeutic targets [PDF]

Exploration of Digestive Diseases
Hepatocellular carcinoma (HCC) functions as a major cancer-related death factor around the world. Research indicates that long non-coding RNAs (lncRNAs) play essential roles during HCC onset and development because they belong to the novel RNA subclass ...
Muhammad Sulaiman, Yimin Nie, Ziyi Chen, Umm E Hani, Faisal Raza, Mussa Mussa Yahya, Zhibo Zhang, Mujahid Sher, Mei Yang, Shengtao Yuan, Chunyu Sun   +10 more
doaj   +1 more source

Multisymbol Time Division Coding for High-Frequency Steady-State Visual Evoked Potential-Based Brain-Computer Interface

IEEE Transactions on Neural Systems and Rehabilitation Engineering, 2022
The optimization of coding stimulus is a crucial factor in the study of steady-state visual evoked potential (SSVEP)-based brain-computer interface(BCI).This study proposed an encoding approach named Multi-Symbol Time Division Coding (MSTDC).
Xiaochen Ye, Chen Yang, Yonghao Chen, Yijun Wang, Xiaorong Gao, Hongxin Zhang   +5 more
doaj   +1 more source