Optogenetic stimulation of cholinergic fibers for the modulation of insulin and glycemia. [PDF]
Sci Rep, 2021 Previous studies have demonstrated stimulation of endocrine pancreas function by vagal nerve electrical stimulation. While this increases insulin secretion, expected concomitant reductions in circulating glucose do not occur. A complicating factor is the
Fontaine AK +9 more
europepmc +8 more sources
Selectively driving cholinergic fibers optically in the thalamic reticular nucleus promotes sleep. [PDF]
Elife, 2016 Cholinergic projections from the basal forebrain and brainstem are thought to play important roles in rapid eye movement (REM) sleep and arousal. Using transgenic mice in which channelrhdopsin-2 is selectively expressed in cholinergic neurons, we show ...
Ni KM +9 more
europepmc +10 more sources
Systematic Regional Variations in the Loss of Cortical Cholinergic Fibers in Alzheimer's Disease [PDF]
Cerebral Cortex, 1996 The loss of cortical cholinergic fibers in Alzheimer's disease was investigated using choline acetyltransferase immunohistochemistry and acetylcholinesterase histochemistry. Within both the normal and Alzheimer's cerebral cortex, the two methods revealed
Changiz Geula, Marsel Mesulam
semanticscholar +5 more sources
The Influence of Resiniferatoxin (RTX) and Tetrodotoxin (TTX) on the Distribution, Relative Frequency, and Chemical Coding of Noradrenergic and Cholinergic Nerve Fibers Supplying the Porcine Urinary Bladder Wall [PDF]
Toxins, 2017 The present study investigated the influence of intravesically instilled resiniferatoxin (RTX) or tetrodotoxin (TTX) on the distribution, number, and chemical coding of noradrenergic and cholinergic nerve fibers (NF) supplying the urinary bladder in ...
Ewa Lepiarczyk +6 more
doaj +3 more sources
Cholinergic Fibers and Muscarinic Receptors in the Central Auditory System
The Journal of Kansai Medical University, 2012 アルツハイマー病では中枢聴覚系の機能障害を示唆する症状を合併する場合が少なくない．また細胞変性等の病変が疾病脳の聴覚上行路各部位にも確認されている．本研究ではマウス脳のこれらの部位におけるコリン線維とムスカリン性受容体（m2，m3タイプ）の発現分布密度を測定した．聴覚上行路諸核で，これらコリン線維・受容体を介する情報伝達・変換が聴覚の伝達に一定の意義を有することが，本研究から強く示唆された．
Satoko Hamada +10 more
semanticscholar +5 more sources
Relationship Between Plaques, Tangles, and Loss of Cortical Cholinergic Fibers in Alzheimer Disease [PDF]
Journal of Neuropathology and Experimental Neurology, 1998 Recent observations in our laboratory have indicated substantial and systematic regional variations in the loss of cortical cholinergic fibers in Alzheimer disease (AD). Previous attempts to study the relationship between cortical cholinergic loss and the density of cortical pathological lesions have resulted in conflicting findings.
Changiz Geula +3 more
semanticscholar +5 more sources
Functional separation of adrenergic and cholinergic fibers to skeletal muscle vessels
American Journal of Physiology-Legacy Content, 1965 The hypothesis that sympathetic innervation to skeletal muscle vasculature contains functionally distinct adrenergic and cholinergic fibers was investigated utilizing the dog isolated perfused grac...
Lawrence D. Dorr, Michael J. Brody
semanticscholar +5 more sources
Formation of eye-specific retinogeniculate projections occurs prior to the innervation of the dorsal lateral geniculate nucleus by cholinergic fibers [PDF]
Thalamus & Related Systems, 2005 We compared the developmental periods in the mouse when projections from the two eyes become segregated in the dorsal lateral geniculate nucleus with the time when this nucleus becomes innervated by cholinergic fibers from the brainstem.
José Manuel Bértolo Ballesteros +2 more
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eLife, 2020 Lateral olivocochlear (LOC) efferent neurons modulate auditory nerve fiber (ANF) activity using a large repertoire of neurotransmitters, including dopamine (DA) and acetylcholine (ACh).
Sherry Jingjing Wu +5 more
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Peripheral cranio-spinal nerve communication for trapezius muscle control using axonal profiling through immunostaining [PDF]
Scientific ReportsAccessory nerve (CNXI) has been known to be the primary conduit for motor control of the trapezius, while the supplementary cervical nerves (C3 and C4) are responsible for processing sensory information from muscle.
Miri Kim +5 more
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