Results 11 to 20 of about 48,172 (247)

Distribution of choline acetyltransferase (ChAT) immunoreactivity in the brain of the teleost Cyprinus carpio [PDF]

open access: yesEuropean Journal of Histochemistry, 2018
Cholinergic systems play a role in basic cerebral functions and its dysfunction is associated with deficit in neurodegenerative disease. Mechanisms involved in human brain diseases, are often approached by using fish models, especially cyprinids, given ...
Arianna Casini   +3 more
doaj   +4 more sources

Axons Giving Rise to the Palisade Endings of Feline Extraocular Muscles Display Motor Features [PDF]

open access: yes, 2013
Palisade endings are nerve specializations found in the extraocular muscles (EOMs) of mammals, including primates. They have long been postulated to be proprioceptors. It was recently demonstrated that palisade endings are cholinergic and that in monkeys
Davis López de Carrizosa, María América   +5 more
core   +1 more source

Acetylcholinesterase-Positive Fiber Deafferentation and Cell Shrinkage in the Septohippocampal Pathway of Aged Amyloid Precursor Protein London Mutant Transgenic Mice

open access: yesNeurobiology of Disease, 2000
Several lines of evidence implicate a cholinergic deficit in Alzheimer's disease (AD). Transgenic mice that overexpress clinical mutants of the human amyloid precursor protein (APP) have been generated that recapitulate many aspects of AD.
Francisca C. Bronfman   +2 more
doaj   +1 more source

Axonal varicosity density as an index of local neuronal interactions. [PDF]

open access: yesPLoS ONE, 2011
Diffuse transmission is an important non-synaptic communication mode in the cerebral neocortex, in which neurotransmitters released from en passant varicosities interact with surrounding cells.
Zi-Wei Zhang   +2 more
doaj   +1 more source

Elevated Levels of miR-144-3p Induce Cholinergic Degeneration by Impairing the Maturation of NGF in Alzheimer’s Disease

open access: yesFrontiers in Cell and Developmental Biology, 2021
Cholinergic degeneration is one of the key pathological hallmarks of Alzheimer’s disease (AD), a condition that is characterized by synaptic disorders and memory impairments. Nerve growth factor (NGF) is secreted in brain regions that receive projections
Lan-Ting Zhou   +16 more
doaj   +1 more source

A Cholinergic Synaptically Triggered Event Participates in the Generation of Persistent Activity Necessary for Eye Fixation [PDF]

open access: yes, 2004
An exciting topic regarding integrative properties of the nervous system is how transient motor commands or brief sensory stimuli are able to evoke persistent neuronal changes, mainly as a sustained, tonic action potential firing.
Alvarado, JC   +5 more
core   +5 more sources

Short-term synaptic plasticity regulates the level of olivocochlear inhibition to auditory hair cells [PDF]

open access: yes, 2011
In the mammalian inner ear, the gain control of auditory inputs is exerted by medial olivocochlear (MOC) neurons that innervate cochlear outer hair cells (OHCs).
Ballestero, Jimena Andrea   +5 more
core   +1 more source

Cholinergic modulation of dopamine overflow in the rat neostriatum: A fast cyclic voltammetric study in vitro [PDF]

open access: yes, 1994
Stimulus-evoked dopamine overflow in rat neostriatal slices was determined using fast cyclic voltammetry. The dopamine efflux induced by intrastriatal stimulation increased with stimulus intensity and was found to be enhanced by more than 100% upon ...
Kudernatsch, Martina, Sutor, Bernd
core   +1 more source

Localization of α-synuclein in teleost central nervous system: immunohistochemical and Western blot evidence by 3D5 monoclonal antibody in the common carp, Cyprinus carpio [PDF]

open access: yes, 2015
Alpha synuclein (α-syn) is a 140 amino acid vertebrate-specific protein, highly expressed in the human nervous system and abnormally accumulated in Parkinson's disease and other neurodegenerative disorders, known as synucleinopathies.
CASINI, Arianna   +6 more
core   +1 more source

Optogenetic stimulation of the brainstem dorsal motor nucleus ameliorates acute pancreatitis

open access: yesFrontiers in Immunology, 2023
IntroductionInflammation is an inherently self-amplifying process, resulting in progressive tissue damage when unresolved. A brake on this positive feedback system is provided by the nervous system which has evolved to detect inflammatory signals and ...
Dane A. Thompson   +21 more
doaj   +1 more source

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