Vegetative innervation of the human vocal larynx
Background. Numerous publications have noted the piano of unequal‑muscular relations arising in the process of vocalization, and described intra‑laryngeal sensitive (afferent) and motor (efferent) nerve endings.
A. Yu. Yurkov+4 more
doaj +1 more source
Cholinergic and dopaminergic projections to the rat medial prefrontal cortex (mPFC) are both involved in cognitive functions including attention. These neuronal systems modulate mPFC neuronal activity mainly through diffuse transmission.
Zi-Wei Zhang+5 more
doaj +1 more source
Axonal varicosity density as an index of local neuronal interactions. [PDF]
Diffuse transmission is an important non-synaptic communication mode in the cerebral neocortex, in which neurotransmitters released from en passant varicosities interact with surrounding cells.
Zi-Wei Zhang+2 more
doaj +1 more source
Protein aggregation and neurodegenerative disease: Structural outlook for the novel therapeutics
Abstract Before the controversial approval of humanized monoclonal antibody lecanemab, which binds to the soluble amyloid‐β protofibrils, all the treatments available earlier, for Alzheimer's disease (AD) were symptomatic. The researchers are still struggling to find a breakthrough in AD therapeutic medicine, which is partially attributable to lack in ...
Sharif Arar+2 more
wiley +1 more source
Localization of α-synuclein in teleost central nervous system: immunohistochemical and Western blot evidence by 3D5 monoclonal antibody in the common carp, Cyprinus carpio [PDF]
Alpha synuclein (α-syn) is a 140 amino acid vertebrate-specific protein, highly expressed in the human nervous system and abnormally accumulated in Parkinson's disease and other neurodegenerative disorders, known as synucleinopathies.
CASINI, Arianna+6 more
core +1 more source
Axons Giving Rise to the Palisade Endings of Feline Extraocular Muscles Display Motor Features [PDF]
Palisade endings are nerve specializations found in the extraocular muscles (EOMs) of mammals, including primates. They have long been postulated to be proprioceptors. It was recently demonstrated that palisade endings are cholinergic and that in monkeys
Davis López de Carrizosa, María América+5 more
core +1 more source
SK2 channels are required for function and long-term survival of efferent synapses on mammalian outer hair cells [PDF]
Cochlear hair cells use SK2 currents to shape responses to cholinergic efferent feedback from the brain. Using SK2-/- mice, we demonstrate that, in addition to their previously defined role in modulating hair cell membrane potentials, SK2 channels are ...
Adelman, John P.+8 more
core +1 more source
Cholinergic modulation of dopamine overflow in the rat neostriatum: A fast cyclic voltammetric study in vitro [PDF]
Stimulus-evoked dopamine overflow in rat neostriatal slices was determined using fast cyclic voltammetry. The dopamine efflux induced by intrastriatal stimulation increased with stimulus intensity and was found to be enhanced by more than 100% upon ...
Kudernatsch, Martina, Sutor, Bernd
core +1 more source
The nicotinic receptor of cochlear hair cells: A possible pharmacotherapeutic target? [PDF]
Mechanosensory hair cells of the organ of Corti transmit information regarding sound to the central nervous system by way of peripheral afferent neurons.
Elgoyhen, Ana Belen+2 more
core +1 more source
Vascular small fiber neuropathy in neuronal intranuclear inclusion disease. [PDF]
Alzheimer's &Dementia, Volume 21, Issue 6, June 2025.
Han Y+7 more
europepmc +2 more sources