Results 1 to 10 of about 2,429,018 (397)

Acetylcholine and cholinergic receptors. [PDF]

open access: yesBrain Neurosci Adv, 2019
This review provides a distillate of the advances in knowledge about the neurotransmitter functions of acetylcholine over the 50-year period between 1967 and 2017, together with incremental information about the cognate nicotinic and muscarinic acetylcholine receptors, and some brief comments on possible advances in the near future.
Brown DA.
europepmc   +7 more sources

Nicotinic Cholinergic Receptors in VTA Glutamate Neurons Modulate Excitatory Transmission [PDF]

open access: yesCell Reports, 2018
Summary: Ventral tegmental area (VTA) glutamate neurons are important components of reward circuitry, but whether they are subject to cholinergic modulation is unknown.
Yijin Yan   +11 more
doaj   +3 more sources

Biological Functions of Keratinocyte Cholinergic Receptors

open access: bronzeJournal of Investigative Dermatology Symposium Proceedings, 1997
Human epidermal keratinocytes possess cholinergic enzymes, which synthesize and degrade acetylcholine, and express both nicotinic and muscarinic classes of cholinergic receptors on their cell surfaces. These receptors bind acetylcholine and initiate cellular response.
Sergei A. Grando
semanticscholar   +5 more sources

Electrophysiology of T lymphocyte cholinergic receptors. [PDF]

open access: greenProceedings of the National Academy of Sciences, 1980
The presence of functional muscarinic-cholinergic receptors on at least some T lymphocytes is suggested by the existence of saturable, high-affinity, specific muscarinic binding in T cell-enriched, but not in B cell-enriched, cell suspensions and by observed cholinergic effects on lymphocytes, (e.g., increased lytic capacity of cytotoxic lymphocytes ...
Howard M. Shapiro, Terry B. Strom
openalex   +4 more sources

Adrenergic and Cholinergic Receptors of Cerebral Microvessels [PDF]

open access: yesJournal of Cerebral Blood Flow & Metabolism, 1981
The presence of α- and β-adrenergic and muscarinic cholinergic receptors in cerebral microvessels of the rat and pig was assessed by ligand binding techniques. The results demonstrate the presence of specific binding to α2- and β-adrenergic receptors but no appreciable specific binding to α1-adrenergic or muscarinic cholinergic receptors.
Shailesh P. Banerjee   +4 more
openaire   +4 more sources

Effects of cholinergic antagonists on ghrelin release and expression in the crop, proventriculus, and duodenum of newly hatched chickens [PDF]

open access: yesFrontiers in Physiology
The aim of this study was to evaluate the effect of the cholinergic receptor antagonists on ghrelin (GHRL) expression and release from parts of the gastrointestinal system in an unique animal model—newly hatched chickens.
Colin Guy Scanes   +2 more
doaj   +2 more sources

Beta-adrenergic and M-cholinergic receptor interactions in the pathogenesis of bronchial obstructive pulmonary diseases [PDF]

open access: yesКлиническая практика, 2020
The crosstalk between the beta-2-adrenoceptor and M- cholinoreceptor systems in the airways plays one of the main roles in the pathogenesis of bronchoobstructive diseases.
Anna V. Eremenko, Kirill A. Zykov
doaj   +1 more source

An original potentiating mechanism revealed by the cryo-EM structures of the human α7 nicotinic receptor in complex with nanobodies

open access: yesNature Communications, 2023
The human α7 nicotinic receptor is a pentameric channel mediating cellular and neuronal communication. It has attracted considerable interest in designing ligands for the treatment of neurological and psychiatric disorders. To develop a novel class of α7
Marie S. Prevost   +11 more
doaj   +1 more source

Cholinergic System and NGF Receptors: Insights from the Brain of the Short-Lived Fish Nothobranchius furzeri

open access: yesBrain Sciences, 2020
Nerve growth factor (NGF) receptors are evolutionary conserved molecules, and in mammals are considered necessary for ensuring the survival of cholinergic neurons.
Paolo de Girolamo   +5 more
doaj   +1 more source

Cholinergic Receptors in Cognitive Disorders [PDF]

open access: yesCanadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 1986
Abstract:Cholinergic receptors (muscarinic subtypes M1 and M2, and putative nicotinic binding) have been examined in the hippocampus obtained at autopsy from a variety of patients with cognitive disorders (Alzheimer's, Parkinson's, and Huntington's diseases, Down's Syndrome and alcoholic dementia) and compared with neurologically normal controls and ...
Perry EK   +8 more
openaire   +2 more sources

Home - About - Disclaimer - Privacy