Imaging Cholinergic Receptors in the Brain by Positron Emission Tomography. [PDF]
J Med Chem, 2023 Cholinergic receptors represent a promising class of diagnostic and therapeutic targets due to their significant involvement in cognitive decline associated with neurological disorders and neurodegenerative diseases as well as cardiovascular impairment ...
Zhang JJ +13 more
europepmc +2 more sources
Acetylcholine and cholinergic receptors. [PDF]
Brain Neurosci Adv, 2019 This review provides a distillate of the advances in knowledge about the neurotransmitter functions of acetylcholine over the 50-year period between 1967 and 2017, together with incremental information about the cognate nicotinic and muscarinic ...
Brown DA.
europepmc +2 more sources
Nicotinic Cholinergic Receptors in VTA Glutamate Neurons Modulate Excitatory Transmission. [PDF]
Cell Rep, 2018 Ventral tegmental area (VTA) glutamate neurons are important components of brain reward circuitry, but whether they are subject to cholinergic modulation is unknown.
Yan Y +11 more
europepmc +2 more sources
Cancer Discovery, 2018 In many solid tumors, parasympathetic input is provided by the vagus nerve, which has been shown to modulate tumor growth. However, whether cholinergic signaling directly regulates progression of pancreatic ductal adenocarcinoma (PDAC) has not been ...
Bernhard W Renz +2 more
exaly +2 more sources
Expression of adrenergic and cholinergic receptors in murine renal intercalated cells. [PDF]
J Vet Med Sci, 2014 Jun JG +5 more
europepmc +3 more sources
Brain muscarinic cholinergic receptors in Huntington's disease [PDF]
, 1992 Muscarinic cholinergic receptors and choline acetyltransferase (ChAT) activity were studied in postmortem brain tissue from patients with Huntington's disease and matched control subjects.
Agid, Y. +4 more
core +1 more source
Cholinergic System and Its Therapeutic Importance in Inflammation and Autoimmunity
Frontiers in Immunology, 2021 Neurological and immunological signals constitute an extensive regulatory network in our body that maintains physiology and homeostasis. The cholinergic system plays a significant role in neuroimmune communication, transmitting information regarding the ...
Namrita Halder, G. Lal
semanticscholar +1 more source
Interactions between the neuromodulatory systems and the amygdala: exploratory survey using the Allen Mouse Brain Atlas. [PDF]
, 2013 Neuromodulatory systems originate in nuclei localized in the subcortical region of the brain and control fundamental behaviors by interacting with many areas of the central nervous system.
Krichmar, Jeffrey L, Zaldivar, Andrew
core +1 more source
Elevated Hippocampal Cholinergic Neurostimulating Peptide precursor protein (HCNP-pp) mRNA in the amygdala in major depression [PDF]
, 2015 The amygdala is innervated by the cholinergic system and is involved in major depressive disorder (MDD). Evidence suggests a hyper-activate cholinergic system in MDD.
Argibay, Pablo +3 more
core +1 more source
A Cholinergic Synaptically Triggered Event Participates in the Generation of Persistent Activity Necessary for Eye Fixation [PDF]
, 2004 An exciting topic regarding integrative properties of the nervous system is how transient motor commands or brief sensory stimuli are able to evoke persistent neuronal changes, mainly as a sustained, tonic action potential firing.
Alvarado, Juan Carlos +5 more
core +4 more sources