Results 141 to 150 of about 2,475,404 (303)

Pharmacologic activation of cholinergic alpha7 nicotinic receptors mitigates depressive-like behavior in a mouse model of chronic stress [PDF]

, 2017
Dan Zhao, Xulin Xu, Lin-na Pan, Wei Zhu, Xiaopei Fu, Lianjun Guo, Qing Lü, Jian Wang   +7 more
openalex   +1 more source

Preclinical models for evaluating psychedelics in the treatment of major depressive disorder

British Journal of Pharmacology, EarlyView.
Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander, Dasha Anderson, Luke Baxter, Matthew Claydon, James Rucker, Emma S. J. Robinson   +5 more
wiley   +1 more source

Positive Allosteric Modulation of Cholinergic Receptors Improves Spatial Learning after Cortical Contusion Injury in Mice. [PDF]

J Neurotrauma, 2019
Holschneider DP, Guo Y, Wang Z, Vidal M, Scremin OU.   +4 more
europepmc   +1 more source

Neurophysiological responses to stressful motion and anti-motion sickness drugs as mediated by the limbic system [PDF]

Performance is characterized in terms of attention and memory, categorizing extrinsic mechanism mediated by ACTH, norepinephrine and dopamine, and intrinsic mechanisms as cholinergic.
Kohl, R. L., Odell, S.
core   +1 more source

Kinetics of agonist-mediated transitions in state of the cholinergic receptor.

, 1977
Gregory A. Weiland, Barla Georgia, S.E. Lappi, Colin F. Chignell, Palmer Taylor   +4 more
openalex   +1 more source

Receptor occupancy dose—response curve suggests that phosphatidyl‐inositol breakdown may be intrinsic to the mechanism of the muscarinic cholinergic receptor [PDF]

, 1976
Robert H. Michell, SHAMSHAD S. JAFFERJI, Lynne Jones   +2 more
openalex   +1 more source

Anti‐inflammatory effects of physical stimuli: The central role of networks in shaping the future of pharmacological research

British Journal of Pharmacology, EarlyView.
Addressing complexity in the study of life sciences through Systems Biology and Systems Medicine has been transformative, making Systems Pharmacology the next logical step. In this review, we focus on physical stimuli, whose potential in pharmacology has been neglected, despite demonstrated therapeutic properties.
Veronica Paparozzi, Reyhaneh Hooshmandabbasi, Alessandro Ravoni, Ying Ma, Luigi Manni, Timothy J. Koh, Caroline Maake, Tiziana Guarnieri, Darong Lai, Vitalii Zablotskii, Christine Nardini   +10 more
wiley   +1 more source

Activation of M1 cholinergic receptors in mouse somatosensory cortex enhances information processing and detection behaviour. [PDF]

Commun Biol
Mishra W, Kheradpezhouh E, Arabzadeh E.
europepmc   +1 more source

Septal Cholinergic Neuromodulation Tunes the Astrocyte-Dependent Gating of Hippocampal NMDA Receptors to Wakefulness

, 2017
Thomas Papouin, Jaclyn M. Dunphy, Michaela Tolman, Kelly T. Dineley, Philip G. Haydon   +4 more
openalex   +1 more source

<p>Association of Cholinergic Muscarinic M4 Receptor Gene Polymorphism with Schizophrenia</p>

, 2020
Ivan V. Pozhidaev, Anastasiia S. Boiko, A.J.M. Loonen, Diana Z. Paderina, Olga Fedorenko, Gennadiy Tenin, Elena G. Kornetova, A. Semke, Н. А. Бохан, Bob Wilffert, Svetlana А. Ivanova   +10 more
openalex   +2 more sources