Results 191 to 200 of about 2,429,018 (397)
Calcium Channel Blockade with Verapamil: Effects on Blood Pressure, Renal, and Myocardial Adrenergic, Cholinergic, and Calcium Channel Receptors in Inbred Dahl Hypertension-Sensitive (S/JR) and Hypertension-Resistant (R/JR) Rats [PDF]
, 1988 James A. McCaughran, C. J. Juno
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Brain Pathology, EarlyView.HSV‐1 infection alters MAPT splicing and promotes Tau pathology in neural models of Alzheimer's disease. HSV‐1 infection in brain organoids and neuronal models increase 4R‐MAPT splicing and Tau hyperphosphorylation. HSV‐1 ICP27 is both necessary and sufficient for inducing these changes highlighting the potential role of HSV‐1 in Alzheimer's disease ...
Emmanuel C. Ijezie +9 more
wiley +1 more source
Brain Pathology, EarlyView.(A) PPN‐cholinergic neurons degenerate during PD. We stereologically counted their rostro‐caudal distribution in post‐mortem PPNs in health versus PD. (Bi) Serial PPN‐containing samples were cholinergic antibody‐DAB stained. (Bii) Only DAB‐stained neurons on green lines and inside the box were counted.
Puneet Kumar Sharma +3 more
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Complete and selective cholinergic denervation of rat neocortex and hippocampus but not amygdala by an immunotoxin against the p75 NGF receptor [PDF]
, 1994 Stephan Heckers +5 more
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Cerebellar defects are a primary pathology in mouse models of spinal muscular atrophy
Brain Pathology, EarlyView.Purkinje cell (PC) degeneration is localized to posterior lobules in the cerebellum, and rescue of survival motor neuron protein expression levels in motor neurons does not ameliorate this effect. Representative images of sagittal cerebellar sections stained with anti‐calbindin in the vermis and hemisphere at P12 for wild type, ChATCre+ rescue (Rescue),
Nicholas C. Cottam +9 more
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Evidence for metabotropic function of epithelial nicotinic cholinergic receptors in rat colon. [PDF]
Br J Pharmacol, 2019 Lottig L, Bader S, Jimenez M, Diener M.
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Preclinical models for evaluating psychedelics in the treatment of major depressive disorder
British Journal of Pharmacology, EarlyView.Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander +5 more
wiley +1 more source