Results 101 to 110 of about 124,021 (305)

Free-water imaging reveals cholinergic pathway damage in multiple system atrophy

Neurobiology of Disease
Background: Dysfunction of the cholinergic system is implicated in the pathophysiology of Multiple System Atrophy (MSA). However, in vivo assessment of cholinergic pathways originating from the nucleus basalis of Meynert (NBM) and pedunculopontine ...
Yao Wang, Han Zhang, Shan Ren, Xinning Zhang, Sushi Wang, Weizheng Ran, Wenyang Tian, Ying Zhou, Zhigang Chen   +8 more
doaj   +1 more source

Postnatal exposure to low doses of Chlorpyrifos induces long-term effects on 5C-SRTT learning and performance, cholinergic and GABAergic systems and BDNF expression [PDF]

, 2020
Cristian Pérez-Fernández, Miguel Morales‐Navas, Laia Guardia-Escote, María Teresa Colomina, Estela Giménez, Fernando Sánchez-Santed   +5 more
openalex   +1 more source

Exploring the Impact of Polystyrene Microplastic Beads on Male Gonads of the Marine Mussel, Mytilus galloprovincialis

Environmental Toxicology, EarlyView.
ABSTRACT Plastic, with its remarkable versatility and numerous applications, has greatly benefited humanity. However, its extreme resistance to natural degradation means it persists in the environment for long periods, causing global environmental problems.
Teresa Chianese, Mariachiara Galati, Tiziana Cappello, Maria Maisano, Gennaro Lettieri, Carmela Marinaro, Marina Piscopo, Gianluca Fasciolo, Carlos Gravato, Gaetana Napolitano, Giulia Paolella, Annamaria Locascio, Rosaria Scudiero, Luigi Rosati   +13 more
wiley   +1 more source

Toxicity of Four Common Environmental Chemicals Across Caenorhabditis elegans Life Stages Supporting the One Health Concept

Environmental Toxicology, EarlyView.
ABSTRACT Pesticides and pharmaceuticals are among the most common chemical groups in waterbodies and soils, and their universal distribution raises concerns about potential adverse effects on nontarget organisms and humans. Reproductive output disruption is of particular concern, as it transposes effects from the individual to the next generations at ...
Fábio Campos, Maria D. Pavlaki, Amadeu M. V. M. Soares, Susana Loureiro   +3 more
wiley   +1 more source

The cholinergic system modulates negative BOLD responses in the prefrontal cortex once electrical perforant pathway stimulation triggers neuronal afterdischarges in the hippocampus [PDF]

, 2021
Alberto Arboit, Karla Krautwald, Frank Angenstein   +2 more
openalex   +1 more source

Comprehensive Evaluation of Bisphenol A Toxicity Reveals Neurobehavioral, Metabolic, and Reproductive Impairments in Girardia tigrina

Environmental Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA), a common industrial chemical used in plastics and consumer products, is increasingly detected in aquatic environments, raising serious concerns about its potential ecological impacts. This study evaluated the sublethal and acute toxic effects of BPA on the freshwater planarian Girardia tigrina, a recognized model for ...
Raquel de Jesus Selestrino, Felipe Schaly, Welligton Luciano Braguini   +2 more
wiley   +1 more source

Proteomics Evidence of the Role of TDMQ20 in the Cholinergic System and Synaptic Transmission in a Mouse Model of Alzheimer’s Disease

, 2022
Fanfan Sun, Jie Zhao, Huajie Zhang, Qihui Shi, Yan Liu, Anne Robert, Qiong Liu, Bernard Meunier   +7 more
openalex   +2 more sources

Electrocochleographic Changes Predict an Early Sign of Cochlear Degeneration

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives The purpose of this study is to identify the earliest appearing auditory electrophysiological indicators that change with age progression in young adults with normal hearing, and to analyze the frequency distribution patterns of these markers in the cochlear.
Min‐Fei Qian, Hao Chen, Qi‐Xuan Wang, Ya‐Qi Zhou, Xiao‐Lu Chen, Zhi‐Wu Huang, Ji‐Ping Li   +6 more
wiley   +1 more source

Bidirectional genetic and phenotypic links between smoking and striatal iron content involving dopaminergic and inflammatory pathways

Addiction, EarlyView.
Abstract Background and aims Tobacco smoking is a major risk factor for cardiovascular and lung diseases. A better understanding of its neurobiological underpinnings will benefit the prevention of smoking‐related illnesses and mortality. Previous studies link smoking to increased iron concentration in the striatum, a central component of the brain's ...
Olga Trofimova, Ilaria Iuliani, Sven Bergmann   +2 more
wiley   +1 more source

The potentiating effect of TA-0910, a new TRH analog, on the central muscarinic cholinergic system is probably in part due to its inhibition of desensitization of muscarinic acetyicholine receptors

, 1990
Yukitsuka Kudo, Hiroshi Sumikawa, Ryuichi Ishida   +2 more
openalex   +1 more source