Results 141 to 150 of about 198,632 (298)

Anticholinergic Burden and Botulinum Toxin Needs after Deep Brain Stimulation in Adult and Pediatric Patients with Dystonia

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Anticholinergic medications and botulinum neurotoxin injections are established treatments for dystonia, yet they carry potential side effects and practical challenges. Deep brain stimulation (DBS) is offered in case of poor response to these approaches.
Marcela A. Montiel, Alessandro Magliozzi, Wei Kang Lim, Carolina Gorodetsky, George M. Ibrahim, Alfonso Fasano   +5 more
wiley   +1 more source

A Dopamine-Acetylcholine Cascade: Simulating Learned and Lesion-Induced Behavior of Striatal Cholinergic Interneurons [PDF]

, 2007
The "teaching signal" that modulates reinforcement learning at cortico-striatal synapses may be a sequence composed of an adaptively scaled DA burst, a brief ACh burst, and a scaled ACh pause.
Bullock, Daniel, Tan, Can Ozan
core   +1 more source

Basal Forebrain Volume and Concurrent Hallucinations and Mild Cognitive Impairment in Parkinson's Disease

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Visual hallucinations (VH) and mild cognitive impairment (MCI) often co‐occur in Parkinson's Disease (PD). Each symptom in isolation is associated with cholinergic basal forebrain (BF) atrophy. However, it is unclear whether BF integrity relates to one symptom preferentially or to their co‐occurrence, and whether this relationship ...
Sabrina M. Adamo, Vaishali Mutreja, Marta Statucka, Batu Kaya, Taylor W. Schmitz, Anthony C. Ruocco, Melanie Cohn   +6 more
wiley   +1 more source

Combined Dysfunction of the Amygdala and Nucleus Basalis Underlies Visual Hallucinations in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Visual hallucinations (VHs) are a common feature of Parkinson's disease (PD) believed to arise from disruptions to the functional architecture supporting sensory integration and attentional control. Across synucleinopathies, increased pathological burden in the amygdala and deficits in cholinergic modulation have been linked to VHs.
Anna Ignatavicius, Lachlan Churchill, Jack Anderson, Ajay Konuri, Claire O'Callaghan, Simon J.G. Lewis, Elie Matar   +6 more
wiley   +1 more source

Expression of components of the urothelial cholinergic system in bladder and cultivated primary urothelial cells of the pig [PDF]

, 2019
Dorothea Leonhäuser, Jasmin Kranz, Regina Leidolf, Patrick Arndt, Ulrich Schwantes, Joachim Geyer, Joachim Große   +6 more
openalex   +1 more source

Levodopa Disrupts Activity Patterns and Encoding of Movement in Striatal Cholinergic Interneurons of Behaving Mice

Movement Disorders, EarlyView.
Abstract Objectives Levodopa treatment, the gold standard therapy for Parkinson's disease, can lead to levodopa‐induced dyskinesias (LIDs). Recent studies in acute brain slices have implicated the neural dynamics of striatal cholinergic interneurons (CINs) in the pathophysiology of LID, reporting that their discharge becomes more bursty in dyskinetic ...
Yara Atamna, Lior Tiroshi, Nadine Wattad, Naomi Gilin, Shelly Gilad, Noa Berkowitz, Joshua A. Goldberg   +6 more
wiley   +1 more source

Evidence that muscarinic cholinergic receptors selectively interact with either the cyclic AMP or the inositol phosphate second-messenger response systems

, 1987
J R Hepler, A R Hughes, T K Harden
openalex   +2 more sources

Functional Magnetic Resonance Imaging (fMRI) Signatures of Progression and Phenoconversion in Prodromal Synucleinopathies

Movement Disorders, EarlyView.
Abstract Background Isolated rapid eye movement (REM) sleep behavior disorder (iRBD) is a prodromal manifestation of synucleinopathies and provides a critical window to identify early markers of progression to Parkinson's disease (PD) and dementia with Lewy bodies (DLB).
Lachlan Churchill, Anna Ignatavicius, Ajay Konuri, Jack Anderson, Natasha Taylor, Simon J.G. Lewis, Elie Matar   +6 more
wiley   +1 more source

Cannabinoids And The Cholinergic System [PDF]

, 1981
Edward F. Domino
openalex   +1 more source

Vagus Nerve Stimulation in Movement Disorders, from Principles to a Systematic Review of Evidence

Movement Disorders, EarlyView.
Abstract Background The vagus nerve (VN), the principal component of the parasympathetic branch of the autonomic nervous system (ANS), mediates bidirec communication between the central nervous system (CNS) and peripheral organs. Vagus nerve stimulation (VNS), delivered through invasive (iVNS) or non‐invasive (transcutaneous cervical [tcVNS] and ...
Francesca Proietti, Matteo Maria Ottaviani, Elisabetta Burchi, Giorgio Vivacqua, Gaia Anzini, Riccardo Antonio Ricciuti, Fioravante Capone, Vaughan G. Macefield, Vincenzo Di Lazzaro, Massimo Marano   +9 more
wiley   +1 more source