Results 181 to 190 of about 198,632 (298)

Postnatal choline supplementation improves sleep in a rat model of developmental alcohol exposure

Alcohol, Clinical and Experimental Research, EarlyView.
This study is the first to examine whether postnatal treatment with choline, an essential nutrient, alters sleep in rats exposed to prenatal ethanol. Results illustrate that both developmental alcohol exposure and early nutrition can have long‐lasting and sex‐dependent effects on sleep in adolescents.
Jaclyn B. Hanson, Jessica A. Baker, Daniel S. Whittaker, Jennifer D. Thomas   +3 more
wiley   +1 more source

Light-Activated Pharmacological Tools for Exploring the Cholinergic System. [PDF]

Med Res Rev
Colleoni A, Galli G, Dallanoce C, De Amici M, Gorostiza P, Matera C.   +5 more
europepmc   +1 more source

Evaluation of glycine treatment for reducing alcohol craving and self‐administration in individuals with alcohol use disorder: A human laboratory trial

Alcohol, Clinical and Experimental Research, EarlyView.
This RCT evaluated whether the glycine receptor (GlyR) agonist glycine reduces craving and alcohol intake in individuals with AUD. Despite a preclinical rationale for targeting the GlyR, these parameters were not reduced. Interestingly, glycine weakened the link between alcohol‐induced craving and self‐administration, and baseline glycine levels were ...
Yasmin Olsson, Helga Lidö, Mia Ericson, Bo Söderpalm   +3 more
wiley   +1 more source

Evaluation of Muscarinic M2 Receptor Sites in Basal Forebrain and Brainstem Cholinergic Systems of Behaviorally Characterized Young and Aged Long-Evans Rats

, 1998
Thomas M. Gill, Michela Gallagher
openalex   +1 more source

EEG alpha reactivity and cholinergic system integrity in Lewy body dementia and Alzheimer's disease.

, 2020
Julia Schumacher, Alan Thomas, Luis R. Peraza, Michael Firbank, Ruth Cromarty, Calum A. Hamilton, Paul C. Donaghy, John T. O’Brien, John‐Paul Taylor   +8 more
openalex   +2 more sources

Acetylcholine From Solitary Chemosensory Cell, Not Neuron, Regulates Basal Cell Fate Driving Eosinophilic Chronic Rhinosinusitis With Nasal Polyps

Allergy, EarlyView.
This study identifies that Ach levels are elevated in eCRSwNP and primarily released from SCCs rather than neurons. Ach induces epithelial remodeling in eCRSwNP by binding to M1R/M3R and activating YAP signaling in basal cells, driving basal cell hyperplasia and abnormal differentiation. Blocking M1R/M3R with TB inhibits eCRSwNP progression.
Bowen Zheng, Tao Lu, Ji Wang, Yalan Zhang, Panhui Xiong, Jieyu Zeng, Shuman Li, Yu Jiang, Yijun Liu, Longlan Shu, Yuan Chen, Yin Zhou, Yue Gu, Dayu Guan, Chenxi Li, Lei Zhao, Shujin Wang, Jie Liu, Xia Ke, Yang Shen, Yucheng Yang   +20 more
wiley   +1 more source

Cholinergic System Changes in Dopa-Unresponsive Freezing of Gait in Parkinson's Disease. [PDF]

Mov Disord
Chou KL, Kanel P, van Emde Boas M, Roytman S, Carli G, Albin RL, Bohnen NI.   +6 more
europepmc   +1 more source

An endogenous cholinergic system controls electrical conduction in the heart. [PDF]

Eur Heart J
Xie D, Xiong K, Dong N, Wang G, Zou Q, Shao B, Chen Z, Wang L, Kong Y, Wang X, Su X, Bai W, Yang J, Liu Y, Zhou B, Chen YH.   +15 more
europepmc   +1 more source

Disorders of the Cholinergic System in COVID-19 Era-A Review of the Latest Research. [PDF]

Int J Mol Sci, 2022
Kopańska M, Batoryna M, Bartman P, Szczygielski J, Banaś-Ząbczyk A.   +4 more
europepmc   +1 more source

Genetics of infertility and “assisted fertilization” in the Bible: The case of Abraham and his family

Andrology, EarlyView.
Abstract Couple infertility is a very ancient medical condition. One of the first descriptions of familial infertility/subfertility is contained in the first book of the Bible, Genesis, written in the 10th century BC and reporting tales from the oral tradition even occurred about 800 years earlier.
Manuela Simoni, Frank Tüttelmann, Livio Casarini   +2 more
wiley   +1 more source