Results 141 to 150 of about 90,058 (326)
The esterases of horse blood. 1. The specificity of horse plasma cholinesterase and ali-esterase [PDF]
, 1950 Lucy M. Sturge, V. P. Whittaker
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Synthetic microneurotrophins: Neurotrophin receptors for therapeutics of neurodegenerative diseases
British Journal of Pharmacology, EarlyView.Neurodegenerative disorders are characterised by the chronic progressive degeneration of specific neuronal subtypes, neuroinflammation, myelin damage and synaptic loss. Despite their growing incidence, advancements in effective treatments remain limited, because of lack of knowledge for the aetiology of the diverse pathophysiology to design systematic ...
Ioanna Zota +4 more
wiley +1 more source
Studies on cholinesterase. 10. Return of cholinesterase activity in the rat after inhibition by carbamoyl fluorides [PDF]
, 1956 D. K. Myers
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Association between CMR‐derived hepatic T1‐time, tricuspid regurgitation and survival
European Journal of Clinical Investigation, EarlyView.We investigated the association between tricuspid regurgitation (TR) severity and hepatic T1‐time in 1029 patients undergoing cardiac MRI and echocardiography. Hepatic T1‐time increased progressively with TR severity and remained independently associated after adjusting for NT‐proBNP and right ventricular function. Both TR and hepatic T1‐time predicted
Katharina Mascherbauer +19 more
wiley +1 more source
Epilepsia, EarlyView.Abstract Clinical development of novel antiseizure medications (ASMs) would benefit from an early proof of principle (POP) model. The photosensitivity model, which uses the photoparoxysmal electroencephalographic response (PPR) as a surrogate of seizures, is currently the only human model that allows POP trials of investigational compounds after a ...
Wolfgang Löscher +1 more
wiley +1 more source
CHOLINESTERASE IN NORMAL AND ABNORMAL HUMAN SKELETAL MUSCLE [PDF]
, 1957 Evelyn B. Beckett, G. H. Bourne
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Journal of the American Geriatrics Society, EarlyView.Documented Patient Values and Preferences and Attendance at Goals of Care Conversations. AD/ADRD—Alzheimer's disease and related dementias. ABSTRACT Background Goals of care (GOC) conversations are an evidence‐based practice that help clarify and align patient values and preferences for medical care with treatment options.
Gina Piscitello +5 more
wiley +1 more source
Pseudo-cholinesterase in Rat Erythrocytes [PDF]
, 1956 D. K. DAVIES, J. P. Rutland
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CHOLINESTERASE IN THE IRIS AFTER REMOVAL OF THE CILIARY GANGLION [PDF]
, 1952 Brenda M. Schofield
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Journal of the American Geriatrics Society, EarlyView.ABSTRACT Background Several amyloid targeting therapies have been approved for Alzheimer's disease (AD), including lecanemab (Leqembi). However, real‐world implementation of these drugs has uncovered significant challenges. Methods We conducted a national cross‐sectional survey of healthcare professionals from multiple disciplines participating in the ...
Alison J. O'Donnell +5 more
wiley +1 more source