Results 41 to 50 of about 90,058 (326)

A Smartphone Camera Colorimetric Assay of Acetylcholinesterase and Butyrylcholinesterase Activity

open access: yesSensors, 2021
Acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) can serve as biochemical markers of various pathologies like liver disfunction and poisonings by nerve agents. Ellman’s assay is the standard spectrophotometric method to measure cholinesterase
Miroslav Pohanka, Jitka Zakova
doaj   +1 more source

Potential of Naturally Derived Alkaloids as Multi-Targeted Therapeutic Agents for Neurodegenerative Diseases

open access: yesMolecules, 2021
Alkaloids are a class of secondary metabolites that can be derived from plants, fungi and marine sponges. They are widely known as a continuous source of medicine for the management of chronic disease including cancer, diabetes and neurodegenerative ...
Yew Rong Kong   +5 more
doaj   +1 more source

Low Cholinesterase Is a Potential Poor Prognostic Factor in Colorectal Cancer Presenting With Tumor Markers Negative. [PDF]

open access: yesCancer Rep (Hoboken)
ABSTRACT Background Colorectal cancer (CRC) is the third most common malignant tumor in the world and has the second highest mortality rate. Tumor markers are proteins used to diagnose and monitor cancer. Serum cholinesterase (CHE) is a nutritional indicator indicating the liver''s ability to synthesize proteins and is a predictor of CRC ...
Alburiahi TAH   +6 more
europepmc   +2 more sources

Variation of Cholinesterase-Based Biosensor Sensitivity to Inhibition by Organophosphate Due To Ionizing Radiation

open access: yesSensors, 2009
A cholinesterase based biosensor was constructed in order to assess the effects of ionizing radiation on exposed AChE. Although the primary objective of the experiment was to investigate the effect of ionizing radiation on the activity of the biosensor ...
Miroslav Pohanka, Miroslav Koch
doaj   +1 more source

The Cholinesterase Inhibitory Properties of Stephaniae Tetrandrae Radix

open access: yesMolecules, 2020
Stephaniae tetrandrae radix (STR) is a commonly used traditional Chinese medicine in alleviating edema by inducing diuresis. In the clinic, STR extracts or its components are widely used in the treatment of edema, dysuria, and rheumatism for the ...
Xiang-Peng Kong   +7 more
doaj   +1 more source

Identification of New N-methyl-piperazine Chalcones as Dual MAO-B/AChE Inhibitors

open access: yesPharmaceuticals, 2023
Monoamine oxidase-B (MAO-B), acetylcholinesterase (AChE), and butyrylcholinesterase (BChE) have been considered target enzymes of depression and neurodegenerative diseases, including Alzheimer’s disease (AD).
Ashraf K. El-Damasy   +6 more
doaj   +1 more source

Pesticide Exposure, Behavior of Farmer, and Activity of Cholinesterase Enzyme in Blood of Fertile Women Farmers [PDF]

open access: yes, 2015
Fertile women farmers are risky of suffering decrease of cholinesterase activity due to pesticide exposure. This study aimed to analyze relation between pesticide exposure and the exposure agent to cholinesterase activity of fertile women workers at ...
Fitria, L. (Laila)   +2 more
core   +3 more sources

Synthesis of new metoclopramide derivatives and in vitro evaluation of their human cholinesterases protection against Chlorpyrifos [PDF]

open access: yesالمجلة العراقية للصيدلة, 2011
Objective: The purpose of this study was to synthesize three new derivatives of metoclopramide by diazotization and replacement reactions and then to quantify in vitro their protection effects on blood cholinesterases using chlorpyrifos as a potent ...
Islam Tarik Qasim   +2 more
doaj   +1 more source

Simple and rapid colorimetric method for determination of erythrocyte and plasma cholinesterase activities and comparison with the standard Ellman’s method

open access: yesPublic Health and Toxicology, 2023
Determination of erythrocyte cholinesterase (AChE) and plasma cholinesterase (BChE) activities in human blood has been suggested for the diagnosis of organophosphate pesticide (OP) exposure and intoxication.
Ashwin B. Patel
doaj   +1 more source

Noradrenergic and cholinergic innervation of the normal human heart and changes associated with cardiomyopathy

open access: yesThe Anatomical Record, EarlyView.
Abstract Autonomic nerves are crucial in cardiac function and pathology. However, data on the distribution of cholinergic and noradrenergic nerves in normal and pathologic human hearts is lacking. Nonfailing donor hearts were pressure‐perfusion fixed, imaged, and dissected. Left ventricular cardiomyopathy samples were also obtained.
Peter Hanna   +15 more
wiley   +1 more source

Home - About - Disclaimer - Privacy