Results 21 to 30 of about 77,907 (255)

An investigation of acute effects at various doses of malathion on glucose homeostasis and insulin resistance in rat liver, pancreas and serum [PDF]

, 2020
Objective. This study investigates acute effects of various doses of Malathion on glucose homeostasis and insulin resistance in rat. Methods. Rats were randomly divided into four groups of 6 animals each. Corn oil was given orally to Group 1.
Ekremoğlu, Murat, Pasaoğlu, Hatice, Pasaoğlu, Özge Tuğce, Severcan, Çınar, Şen, Bayram   +4 more
core   +3 more sources

Effects of occupational exposure in pesticide plant on workers' serum and erythrocyte cholinesterase activity [PDF]

, 2007
Objectives: The determination of cholinesterase activity has been commonly applied in the biomonitoring of exposure to organophosphates and carbamates and in the diagnosis of poisoning with anticholinesterase compounds.
Ahmadi, A.R., Joshaghani, H.R., Mansourian, A.R.   +2 more
core   +1 more source

Pyridostigmine in pediatric Intestinal pseudo-obstruction. case report of a 2-year old girl and literature review [PDF]

, 2019
Pediatric chronic intestinal pseudo-obstruction is a rare disorder characterized by a severe impairment of gastrointestinal motility leading to intestinal obstruction symptoms in the absence of mechanical causes.
Caló, Girolamo, De Giorgio, Roberto, Di Nardo, Giovanni, Esposito, Francesco, Morlando, Alessia, Parisi, Pasquale, Stanghellini, Vincenzo, Villa, Maria Pia, Viscogliosi, Federica   +8 more
core   +2 more sources

Plant Terpenoids as the Promising Source of Cholinesterase Inhibitors for Anti-AD Therapy

Biology, 2022
Plant-derived terpenes are the prolific source of modern drugs such as taxol, chloroquine and artemisinin, which are widely used to treat cancer and malaria infections.
Shereen Lai Shi Min, Sook Yee Liew, Nelson Jeng Yeou Chear, Bey Hing Goh, Wen-Nee Tan, Kooi Yeong Khaw   +5 more
doaj   +1 more source

Dried blood spots in toxicology : from the cradle to the grave? [PDF]

, 2012
About a century after its first described application by Ivar Bang, the potential of sampling via dried blood spots (DBS) as an alternative for classical venous blood sampling is increasingly recognized.
De Kesel, Pieter, Ingels, Ann-Sofie, Lambert, Willy, Stove, Christophe   +3 more
core   +1 more source

Assessment of serum level cholinesterase as a biomarker of liver cirrhosis in Egyptian cirrhotic patients

Gastroenterology Insights, 2017
Serum cholinesterase levels are closely correlated with the severity of liver disease. The aim of the paper was to assess the value of serum cholinesterase in evaluating liver reserve function in cirrhotic patients.
Mona A. Amin, Marwa E. El-Shahat, Nouman El-Garem, Ahmed Soliman, Eman Obaia   +4 more
doaj   +1 more source

In Vitro Enzymatic and Kinetic Studies, and In Silico Drug-Receptor Interactions, and Drug-Like Profiling of the 5-Styrylbenzamide Derivatives as Potential Cholinesterase and β-Secretase Inhibitors with Antioxidant Properties

Antioxidants, 2021
The 5-(styryl)anthranilamides were transformed into the corresponding 5-styryl-2-(p-tolylsulfonamido)benzamide derivatives. These 5-styrylbenzamide derivatives were evaluated through enzymatic assays in vitro for their capability to inhibit ...
Malose J. Mphahlele, Emmanuel N. Agbo, Garland K. More, Samantha Gildenhuys   +3 more
doaj   +1 more source

Dysregulated homeostasis of acetylcholine levels in immune cells of RR-multiple sclerosis patients [PDF]

, 2016
Multiple sclerosis (MS) is characterized by pro-inflammatory cytokine production. Acetylcholine (ACh) contributes to the modulation of central and peripheral inflammation.
Biagioni, Stefano, Costantini, Erica, DI BARI, Maria, Di Nicola, Marta, D’Angelo, Chiara, Galizia, Sabrina, Gasperini, Claudio, Orlando, Viviana, Porfilio, Italo, Reale, Marcella, Ruggieri, Serena, Tata, Ada Maria   +11 more
core   +2 more sources

Evaluation of Cholinesterase Activities During in Vivo Intoxication Using an Electrochemical Sensor Strip – Correlation With Intoxication Symptoms

Sensors, 2009
Cholinesterase activity in blood of laboratory rats was monitored. Rats were intoxicated with paraoxon at dosis of 0 – 65 – 125 – 170 – 250 – 500 nmol. The 250 nmol dose was found to be the LD50.
Jana Zdarova-Karasova, Martina Hrabinova, Kamil Kuca, Ladislav Novotný, Jan Misík, Miroslav Pohanka   +5 more
doaj   +1 more source

Evaluation of Toxic Effects Induced by Sub-Acute Exposure to Low Doses of α-Cypermethrin in Adult Male Rats

Toxics, 2022
To contribute new information to the pyrethroid pesticide α-cypermethrin toxicity profile, we evaluated its effects after oral administration to Wistar rats at daily doses of 2.186, 0.015, 0.157, and 0.786 mg/kg bw for 28 days. Evaluations were performed
Vilena Kašuba, Blanka Tariba Lovaković, Ana Lucić Vrdoljak, Anja Katić, Nevenka Kopjar, Vedran Micek, Mirta Milić, Alica Pizent, Davor Želježić, Suzana Žunec   +9 more
doaj   +1 more source