Results 41 to 50 of about 53,217 (270)

Hubungan Usia dan Status Gizi dengan Enzim Cholinesterase pada Pekerja Industri Pembuatan Bahan Baku Cat di Surabaya

Jurnal Kesehatan, 2022
The additive is one component of paint that inhibits the growth of bio-organisms in the finished paint product with pesticide-like properties. Workers in the manufacture of paints are one of the populations that are at risk of being exposed to heavy ...
Chusnul Chotimah, Indah Tri Susilowati
doaj   +1 more source

TRAIP Mediates Alcohol‐Induced Liver Injury through Regulating β‐catenin Ubiquitin Degradation via Direct Interaction

Advanced Science, EarlyView.
This study reveals that NF‐κB1‐driven TRAIP upregulation in ALD correlates with disease severity. Mechanistically, TRAIP directly binds β‐catenin via its CC domain and promotes its K48‐linked ubiquitination and degradation, which is independent of the GSK3β/β‐TrCP pathway.
Zhan Wu, Mingjiang Liu, Lijuan Liao, Zhaohong Mo, Wenli Xu, Linfeng Mao, Yubing Chen, Qiuli Xie, Ming Yao, Shilian Chen, Stephen Tomlinson, Sebastian Mueller, Songqing He, Guandou Yuan   +13 more
wiley   +1 more source

A study of serum amylase as a probable prognostic marker in acute organophosphorus poisoning

APIK Journal of Internal Medicine, 2021
Background and Objectives: Organophosphate compounds are frequently used for homicidal and suicidal purposes, organophosphates account for as many as 80% of pesticide-related hospital admissions.
K R Raveendra, C N Mohan
doaj   +1 more source

EphB1‐Mediated Transient Blood‐Brain Barrier Opening Facilitates a Ferritin‐Based Nanotherapeutic for Alzheimer's Disease

Advanced Science, EarlyView.
We constructed a brain‐targeted AFn‐DPZ nanodrug delivery system and identified EphB1 as its receptor on the blood‐brain barrier (BBB). This system facilitates drug transport across the BBB and thereby ameliorates cognitive impairment in Alzheimer's disease.
Shilin Wen, Jingjing Gao, Zhixian Wang, Qiumin Ma, Xiao‐Ling Xu, Jianer Chen   +5 more
wiley   +1 more source

Innovative Test Strip‐Based Colorimetric Sensors Integrated With Affinity Chromatography: Acetylcholinesterase Inhibitor Screening Breakthrough in Lycium Barbarum Leaves

Advanced Science, EarlyView.
Schematic diagrams illustrating the breakthrough in the screening of AChE inhibitors from LBL, and the research process of the pharmacodynamics of the NCP are presented. ABSTRACT Current Alzheimer's drugs exhibit limited effectiveness, highlighting the necessity for multi‐target treatments.
Yuping Sa, Hui Yuan, Jingui Ma, Zhigang Yang, Mei Wang, Weibiao Wang, Lingling Yang, Fen Ma, Weiman Zhang, Gidion Wilson Mening'oo, Guoning Chen, Xueqin Ma   +11 more
wiley   +1 more source

The association between preoperative serum cholinesterase and all-cause mortality in geriatric patients with hip fractures: a cohort study of 2387 patients

Perioperative Medicine
Objective This study is to evaluate the association between preoperative cholinesterase levels and all-cause mortality in geriatric hip fractures. Methods Elderly patients with hip fractures were screened between Jan 2015 and Sep 2019.
Yan-Ning Zhang, Peng Xiao, Bin-Fei Zhang
doaj   +1 more source

Early Spatial and Contextual Coding Deficits in Hippocampal CA1 Precede Performance Decline in an Alzheimer's Disease Model

Advanced Science, EarlyView.
Two‐photon calcium imaging in behaving 5xFAD mice reveals early CA1 coding deficits before behavioral decline. Task‐related place cell activity and splitter cell trajectory coding are impaired, with reduced retrospective dominance and greater prospective weighting.
Yimei Li, Mary Ann Go, Hualong Zhang, Robertas Aleksynas, Juliana Kim, Mingyang Gao, Seigfred Prado, Magdalena Sastre, Simon R. Schultz   +8 more
wiley   +1 more source

Serum Cholinesterase Activity in Elderly Female Patients with Different Screening Cognitive Status and Frailty Assessment Scores [PDF]

Анналы клинической и экспериментальной неврологии
Introduction. Frailty and mild cognitive impairment (MCI) are common geriatric syndromes. Peripheral serum cholinesterase (pChE) is a laboratory indicator that may reflect dysfunction of cholinergic processes in the central nervous system. Published data
Anton N. Kodincev, Larisa I. Volkova
doaj   +1 more source

Nanoparticulate transport of oximes over an in vitro blood-brain barrier model [PDF]

, 2010
Background: Due to the use of organophosphates (OP) as pesticides and the availability of OP-type nerve agents, an effective medical treatment for OP poisonings is still a challenging problem.
Tikva Vogel, Kreuter, Jörg (Prof. Dr.), Sascha Wien, Zensi, Anja, Kufleitner, Jürgen, Jörg Kreuter, Wien, Sascha, Jürgen Kufleitner, Bungert, Judith, Wagner, Sylvia, Judith Bungert, Dadparvar, Miriam, Vogel, Tikva, Anja Zensi, Sylvia Wagner, Worek, Franz, Miriam Dadparvar, Hagen von Briesen, Briesen, Hagen von, Franz Worek   +19 more
core   +2 more sources

Inhibition of human motor endplate cholinesterase by anticholinesterase compounds. [PDF]

, 1982
The inhibition of human motor endplate cholinesterase by anticholinesterase compounds was studied using isolated muscle membrane preparation. Ambenonium was most potent, and edrophonium was least potent in inhibiting motor endplate cholinesterase.
Fujii, Masafumi, Namba, Tatsuji
core   +1 more source