Results 1 to 10 of about 23,989 (206)

Potential revival of cholinesterase inhibitors as drugs in veterinary medicine [PDF]

Frontiers in Veterinary Science, 2023
The cholinergic system is involved in the regulation of all organ systems and has acetylcholine (ACh) as almost its only neurotransmitter. Any substance is called cholinergic if it can alter the action of acetylcholine. Cholinesterases (ChEs) are enzymes
Neža Žnidaršič, Malan Štrbenc, Neža Grgurevič, Tomaž Snoj   +3 more
doaj   +2 more sources

Cholinesterase Inhibitors from Plants and Their Potential in Alzheimer’s Treatment: Systematic Review [PDF]

Brain Sciences
Introduction: Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by memory loss and cognitive decline, primarily due to dysfunction of acetylcholine caused by acetylcholinesterase and butyrylcholinesterase.
Maryam N. ALNasser, Ghadir M. Alboraiy, Eman M. Alsowig, Fatimah M. Alqattan   +3 more
doaj   +2 more sources

Clinical Signs of Poisoning with Pyrethroid and Cholinesterase Inhibitors

مجله دانشکده پزشکی اصفهان, 2011
Background: Due to the similarities between clinical signs of toxicity with pyrethroids and cholinesterase inhibitors, if the mistake between these two was made and the patient was treatment with atropine, severe atropine poisoning and even death could ...
Farzad Gheshlaghi, Zohreh Sedighinia
doaj   +1 more source

A New Class of Benzo[b]thiophene-chalcones as Cholinesterase Inhibitors: Synthesis, Biological Evaluation, Molecular Docking and ADME Studies [PDF]

Molecules
In this study, heterocyclic compounds containing a benzothiophene scaffold were designed and synthetized, and their inhibitory activity against cholinesterases (ChE) and the viability of SH-SY5Y cells have been evaluated.
Giovanna Lucia Delogu, Michela Begala, Maria João Matos, Davide Crucitti, Valeria Sogos, Benedetta Era, Antonella Fais   +6 more
doaj   +2 more sources

Dynamic associations of cholinesterase inhibitors and memantine with cognitive trajectories in individuals with Alzheimer's or mixed dementia: a real-world analysis using the quality registry SveDem. [PDF]

Alzheimers Res Ther
Chen C, Mo M, Åkerman M, Garcia-Ptacek S, Xu H, Eriksdotter M.   +5 more
europepmc   +2 more sources

Clinical Practice Guidelines for Dementia: Recommendations for Cholinesterase Inhibitors and Memantine. [PDF]

Dement Neurocogn Disord
Kim Y, Kang DW, Kim GH, Kim KW, Kim HJ, Na S, Park KH, Park YH, Byeon G, Suh J, Shin JH, Shim Y, Yang Y, Um YH, Oh SI, Wang SM, Yoon B, Lee SM, Lee J, San Lee J, Lim JS, Jung YH, Chin J, Jang H, Choi M, Hong YJ, Rhee HY, Jang JW, Korean Dementia Association.   +28 more
europepmc   +3 more sources

Can Marine Products Improve Alzheimer’s Disease [PDF]

Journal of Sciences, Islamic Republic of Iran, 2020
Alzheimer's disease is an irreversible chronic neurodegenerative disease which is the most common cause of dementia among older adults. According to amyloid hypothesis, cholin neurotransmitters have important roles in CNS memory function, therefore ...
Hamid-Reza Adhami, Paria Sharafi
doaj   +1 more source

Plant Terpenoids as the Promising Source of Cholinesterase Inhibitors for Anti-AD Therapy

Biology, 2022
Plant-derived terpenes are the prolific source of modern drugs such as taxol, chloroquine and artemisinin, which are widely used to treat cancer and malaria infections.
Shereen Lai Shi Min, Sook Yee Liew, Nelson Jeng Yeou Chear, Bey Hing Goh, Wen-Nee Tan, Kooi Yeong Khaw   +5 more
doaj   +1 more source

Cholinesterase inhibitors and hospitalization for bradycardia: a population-based study. [PDF]

PLoS Medicine, 2009
BACKGROUND: Cholinesterase inhibitors are commonly used to treat dementia. These drugs enhance the effects of acetylcholine, and reports suggest they may precipitate bradycardia in some patients.
Laura Y Park-Wyllie, Muhammad M Mamdani, Ping Li, Sudeep S Gill, Andreas Laupacis, David N Juurlink   +5 more
doaj   +1 more source

Acetyl-cholinesterase-inhibitors reconsidered. A narrative review of post-marketing studies on Alzheimer's disease. [PDF]

Aging Clin Exp Res
Zuliani G, Zuin M, Romagnoli T, Polastri M, Cervellati C, Brombo G.   +5 more
europepmc   +2 more sources