Results 1 to 10 of about 2,781,261 (274)
Plant Terpenoids as the Promising Source of Cholinesterase Inhibitors for Anti-AD Therapy
Biology, 2022 Plant-derived terpenes are the prolific source of modern drugs such as taxol, chloroquine and artemisinin, which are widely used to treat cancer and malaria infections.
Shereen Lai Shi Min +5 more
doaj +2 more sources
Adverse Effects of Cholinesterase Inhibitors in Dementia, According to the Pharmacovigilance Databases of the United-States and Canada. [PDF]
PLoS ONE, 2015 This survey analyzes two national pharmacovigilance databases in order to determine the major adverse reactions observed with the use of cholinesterase inhibitors in dementia.
Thibault B Ali +4 more
doaj +2 more sources
International Journal of Neuropsychopharmacology, 2017 Background: We investigated the effect of cholinesterase inhibitors on all-cause discontinuation, efficacy and safety, and the effects of study design-, intervention-, and patient-related covariates on the risk-benefit of cholinesterase inhibitors for ...
Lidia Blanco-silvente +2 more
exaly +2 more sources
Long-term Effects of Cholinesterase Inhibitors on Cognitive Decline and Mortality
Neurology, 2021 Objective To investigate whether cholinesterase inhibitors (ChEIs) are associated with slower cognitive decline in Alzheimer dementia and decreased risk of severe dementia or death.
Hong Xu +5 more
semanticscholar +1 more source
Potential revival of cholinesterase inhibitors as drugs in veterinary medicine
Frontiers in Veterinary Science, 2023 The cholinergic system is involved in the regulation of all organ systems and has acetylcholine (ACh) as almost its only neurotransmitter. Any substance is called cholinergic if it can alter the action of acetylcholine. Cholinesterases (ChEs) are enzymes
Neža Žnidaršič +3 more
doaj +1 more source
Can Marine Products Improve Alzheimer’s Disease [PDF]
Journal of Sciences, Islamic Republic of Iran, 2020 Alzheimer's disease is an irreversible chronic neurodegenerative disease which is the most common cause of dementia among older adults. According to amyloid hypothesis, cholin neurotransmitters have important roles in CNS memory function, therefore ...
Hamid-Reza Adhami, Paria Sharafi
doaj +1 more source
Cholinesterase inhibitors and memantine for the treatment of Alzheimer and non-Alzheimer dementias.
Ideggyógyászati Szemle, 2021 In aging societies, the morbidity and mortality of dementia is increasing at a significant rate, thereby imposing burden on healthcare, economy and the society as well.
N. Balázs, D. Bereczki, T. Kovács
semanticscholar +1 more source
In vitro inhibition of human blood cholinesterases and protection against chlorpyriphos (organophosphate) by weak anticholinesterase drugs [PDF]
المجلة العراقية للصيدلة, 2011 In vitro inhibition of human plasma and erythrocyte cholinesterase activities by the strong cholinesterase inhibitor chlorpyriphos (organophosphate) and the weak cholinesterase inhibitors (donepezil, metoclopramide, and diphenhydramine) in different ...
Ahmed A.J. Mahmood
doaj +1 more source
Cochrane Database of Systematic Reviews, 2021 BACKGROUND Dementia is a progressive syndrome characterised by deterioration in memory, thinking and behaviour, and by impaired ability to perform daily activities. Two classes of drug - cholinesterase inhibitors (donepezil, galantamine and rivastigmine)
C. Parsons +6 more
semanticscholar +1 more source
British medical journal, 2021 Objective To evaluate the association between the use of antipsychotic drugs and cholinesterase inhibitors and the risk of falls and fractures in elderly patients with major neurocognitive disorders. Design Self-controlled case series.
Grace Hsin-Min Wang +4 more
semanticscholar +1 more source