Results 21 to 30 of about 42,628 (216)

An examination of three prescribing cascades in a cohort of older adults with dementia

open access: yesBMC Geriatrics, 2021
Background Prescribing cascades are a source of inappropriate prescribing for older adults with dementia. We aimed to study three prescribing cascades in older Nova Scotians with dementia using administrative databases.
Shanna C. Trenaman   +3 more
doaj   +1 more source

The effects of donepezil in Alzheimer's disease - Results from a multinational trial [PDF]

open access: yes, 1999
Donepezil has been shown to be well tolerated and to improve cognition and global function in patients with mild to moderately severe Alzheimer's disease (AD).
Burns, A.   +7 more
core   +1 more source

Clinical practice with anti-dementia drugs: A revised (third) consensus statement from the British Association for Psychopharmacology [PDF]

open access: yes, 2017
The British Association for Psychopharmacology coordinated a meeting of experts to review and revise its previous 2011 guidelines for clinical practice with anti-dementia drugs. As before, levels of evidence were rated using accepted standards which were
Burns, A   +13 more
core   +2 more sources

Understanding Alzheimer disease

open access: yesSouth African Family Practice, 2019
Alzheimer disease (AD) is a neurodegenerative disorder with an uncertain pathogenesis. It is characterised by symptoms of memory impairment, executive dysfunction and visuospatial impairment.
M. Vally, F. Kathrada
doaj   +1 more source

An Overview of 1,2,3-triazole-Containing Hybrids and Their Potential Anticholinesterase Activities

open access: yesPharmaceuticals, 2023
Acetylcholine (ACh) neurotransmitter of the cholinergic system in the brain is involved in learning, memory, stress responses, and cognitive functioning.
Shah Alam Khan   +4 more
doaj   +1 more source

Metabolite profile and in vitro cholinesterase inhibitory activity of extract and fractions of Aaptos suberitoides [PDF]

open access: yesJournal of Pharmacy & Pharmacognosy Research, 2023
Context: Marine sources such as sponges have shown a significant impact on the drug development from nature. Metabolites isolated from sponges show diversity in terms of structural features and pharmacological properties.
Hanifa R. Putri   +7 more
doaj   +1 more source

The influence of in vitro gastrointestinal digestion on the chemical composition and antioxidant and enzyme inhibitory capacities of carob liqueurs obtained with different elaboration techniques [PDF]

open access: yes, 2019
Carob liqueur is a traditional Mediterranean alcoholic beverage obtained via a wide range of production techniques contributing to the different organoleptic attributes of the final product.
Coelho, Natacha   +5 more
core   +1 more source

Cholinesterase inhibitors for delirium [PDF]

open access: yesCochrane Database of Systematic Reviews, 2005
Delirium is now the preferred term to describe acute confusional states. It is experienced by 10 to 30% of all hospital inpatients. Delirium is potentially reversible and is related to several adverse outcomes, including increased hospital length of stay, poor functional status, persistent cognitive impairment, need for institutional care and probably ...
R, Overshott, S, Karim, A, Burns
openaire   +2 more sources

Design, synthesis and biological evaluation of 1,3-dihydroxyxanthone derivatives: Effective agents against acetylcholinesterase [PDF]

open access: yes, 2017
The present work concerns the rational design and development of new inhibitors of acetylcholinesterase (AChE) based on the privileged xanthone scaffold.
Accordino, Sebastian Roberto   +5 more
core   +1 more source

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