An examination of three prescribing cascades in a cohort of older adults with dementia
Background Prescribing cascades are a source of inappropriate prescribing for older adults with dementia. We aimed to study three prescribing cascades in older Nova Scotians with dementia using administrative databases.
Shanna C. Trenaman +3 more
doaj +1 more source
Resposta à Carta ao Editor Relativa ao Trabalho “Prescrição Inapropriada em Idosos numa Enfermaria de Medicina Interna” Mariana Alves, Marco Ribeiro Narciso, Teresa Fonseca, João Gorjão Clara” [Acta Med Port.2019;32:249-249] [PDF]
info:eu-repo/semantics ...
Urzal, JI
core +1 more source
The effects of donepezil in Alzheimer's disease - Results from a multinational trial [PDF]
Donepezil has been shown to be well tolerated and to improve cognition and global function in patients with mild to moderately severe Alzheimer's disease (AD).
Burns, A. +7 more
core +1 more source
Clinical practice with anti-dementia drugs: A revised (third) consensus statement from the British Association for Psychopharmacology [PDF]
The British Association for Psychopharmacology coordinated a meeting of experts to review and revise its previous 2011 guidelines for clinical practice with anti-dementia drugs. As before, levels of evidence were rated using accepted standards which were
Burns, A +13 more
core +2 more sources
Understanding Alzheimer disease
Alzheimer disease (AD) is a neurodegenerative disorder with an uncertain pathogenesis. It is characterised by symptoms of memory impairment, executive dysfunction and visuospatial impairment.
M. Vally, F. Kathrada
doaj +1 more source
An Overview of 1,2,3-triazole-Containing Hybrids and Their Potential Anticholinesterase Activities
Acetylcholine (ACh) neurotransmitter of the cholinergic system in the brain is involved in learning, memory, stress responses, and cognitive functioning.
Shah Alam Khan +4 more
doaj +1 more source
Metabolite profile and in vitro cholinesterase inhibitory activity of extract and fractions of Aaptos suberitoides [PDF]
Context: Marine sources such as sponges have shown a significant impact on the drug development from nature. Metabolites isolated from sponges show diversity in terms of structural features and pharmacological properties.
Hanifa R. Putri +7 more
doaj +1 more source
The influence of in vitro gastrointestinal digestion on the chemical composition and antioxidant and enzyme inhibitory capacities of carob liqueurs obtained with different elaboration techniques [PDF]
Carob liqueur is a traditional Mediterranean alcoholic beverage obtained via a wide range of production techniques contributing to the different organoleptic attributes of the final product.
Coelho, Natacha +5 more
core +1 more source
Cholinesterase inhibitors for delirium [PDF]
Delirium is now the preferred term to describe acute confusional states. It is experienced by 10 to 30% of all hospital inpatients. Delirium is potentially reversible and is related to several adverse outcomes, including increased hospital length of stay, poor functional status, persistent cognitive impairment, need for institutional care and probably ...
R, Overshott, S, Karim, A, Burns
openaire +2 more sources
Design, synthesis and biological evaluation of 1,3-dihydroxyxanthone derivatives: Effective agents against acetylcholinesterase [PDF]
The present work concerns the rational design and development of new inhibitors of acetylcholinesterase (AChE) based on the privileged xanthone scaffold.
Accordino, Sebastian Roberto +5 more
core +1 more source

